The conversion of androstenedione (ANDST) to estrone (E1) is catalysed by aromatase (CYP19A1) associated with the endoplasmic reticulum membrane (Toda et al. 1990, Simpson et al. 1994).
Michael, MD, Bulun, SE, Graham-Lorence, S, Simpson, ER, Amarneh, B, Mendelson, CR, Fisher, CR, Mahendroo, MS, Ito, Y, Means, GD, Hinshelwood, MM, Kilgore, MW
Yamamoto, Y, Toda, K, Sagara, Y, Kuribayashi, I, Terashima, M, Sumimoto, H, Kawamoto, T, Maeda, T, Yokoyama, Y, Mitsuuchi, Y
steroid hydroxylase activity of CYP19A1 [endoplasmic reticulum membrane]
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