Methylselenocysteine (MeSec) undergoes an alpha,gamma-elimination reaction by cystathionine gamma-lyase (CTH) to produce methylselenol aka methaneselenol (MeSeH), ammonia, and pyruvic acid. This reaction is inferred from the event in rat involving the protein cystathionine gamma-lyase (Cth) (Pinto et al. 2011, Suzuki et al. 2007).
Suzuki, KT, Suzuki, N, Kurasaki, K
Cooper, AJ, Sinha, R, Lee, JI, Pinto, JT, MacEwan, ME
methylselenocysteine deselenhydrase activity of PXLP-K212-CTH tetramer [cytosol]
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