Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)

Stable Identifier
R-HSA-2161795
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cytochrome P450s 1A1 (CYP1A1), 1A2 (CYP1A2), and 1B1 (CYP1B1) convert arachidonic acid to 16-, 17-, and 18-hydroxyeicosatetraenoic acids (16-, 17-, and 18-HETEs) (Choudhary et al. 2004).

Literature References
PubMed ID Title Journal Year
15258110 Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1

Choudhary, D, Jansson, I, Stoilov, I, Sarfarazi, M, Schenkman, JB

Drug Metab Dispos 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
monooxygenase activity of CYP(1) [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created