Mannose 1-phosphate is converted to GDP-Mannose by mannose-1-phosphate guanyltransferase alpha and beta forms (GMPPA/B). This enzyme had originally been characterized from rat and bovine sources (Verachtert H et al, 1966) and more recently from pig (Ning B and Elbein AD, 2000).
Elbein, AD, Ning, B
Verachtert, H, Hansen, RG, Rodriguez, P, Bass, ST
mannose-1-phosphate guanylyltransferase activity of GMPPA/B [cytosol]
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