NADPH transfers electrons to FDXR

Stable Identifier
R-HSA-2395517
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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NADPH transfers electrons to FDXR
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Two electrons and one proton are transferred from NADPH to the FAD moiety of ferredoxin reductase. A proton from the medium is also taken up by ferredoxin reductase.
Literature References
PubMed ID Title Journal Year
1567230 Expression and characterization of human mitochondrial ferredoxin reductase in Escherichia coli

Brandt, ME, Vickery, LE

Arch. Biochem. Biophys. 1992
Participants
Input
Output
Participates
as an event of
Catalyst Activity

ferredoxin-NADP+ reductase activity of FDXR [mitochondrial matrix]

Physical Entity
FDXR [mitochondrial matrix] (Homo sapiens)
Activity
ferredoxin-NADP+ reductase activity (GO:0004324)
Orthologous Events
NADPH transfers electrons to FDXR (Bos taurus)
NADPH transfers electrons to FDXR (Caenorhabditis elegans)
NADPH transfers electrons to FDXR (Canis familiaris)
NADPH transfers electrons to FDXR (Danio rerio)
NADPH transfers electrons to FDXR (Dictyostelium discoideum)
NADPH transfers electrons to FDXR (Drosophila melanogaster)
NADPH transfers electrons to FDXR (Gallus gallus)
NADPH transfers electrons to FDXR (Mus musculus)
NADPH transfers electrons to FDXR (Plasmodium falciparum)
NADPH transfers electrons to FDXR (Rattus norvegicus)
NADPH transfers electrons to FDXR (Saccharomyces cerevisiae)
NADPH transfers electrons to FDXR (Schizosaccharomyces pombe)
NADPH transfers electrons to FDXR (Sus scrofa)
NADPH transfers electrons to FDXR (Xenopus tropicalis)
Authored
Lill, R  (2012-09-24)
May, B  (2011-06-04)
Reviewed
Rouault, TA  (2012-10-12)
Tong, WH  (2012-10-12)
Hill, DP  (2025-06-16)
Created
May, B  (2012-07-02)
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