PI4KB binds to ARF1/3:GTP at the Golgi membrane

Stable Identifier
Reaction [binding]
Homo sapiens
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At the Golgi membrane, ADP-ribosylation factor 1 and 3 (ARF1 and ARF3) complexed to GTP bind to phosphatidylinositol 4-kinase beta (PI4KB) and activate it (Haynes et al. 2007, Wong et al. 1997, Godi et al. 1999).

Literature References
PubMed ID Title Journal Year
10559940 ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex

Godi, A, Pertile, P, Meyers, R, Marra, P, Di Tullio, G, Iurisci, C, Luini, A, Corda, D, De Matteis, MA

Nat Cell Biol 1999
9148941 Subcellular locations of phosphatidylinositol 4-kinase isoforms

Wong, K, Meyers, ddR, Cantley, LC

J Biol Chem 1997
17555535 Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta

Haynes, LP, Sherwood, MW, Dolman, NJ, Burgoyne, RD

Traffic 2007
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