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About
What is Reactome ?
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Team
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Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
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Table of Contents
DOIs
Data Schema
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Analysis Data
Analysis Gene Expression
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Citing us
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GTP [cytosol]
Stable Identifier
R-ALL-29438
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Guanosine 5'-triphosphate, GTP)(4-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Active MTORC1 phosphorylates ULK1 (Bos taurus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
RAN:GTP recruits nuclear envelope (NE) membranes (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)
GTP [cytosol]
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Mitotic Prophase (Bos taurus)
Golgi Cisternae Pericentriolar Stack Reorganization (Bos taurus)
PLK1 phosphorylates GORASP1 (Bos taurus)
p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
p-RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP [Golgi membrane] (Bos taurus)
p-RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds microtubule lattice in interphase cells (Bos taurus)
GTSE1:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to starvation (Bos taurus)
Amino acids regulate mTORC1 (Bos taurus)
RRAGA,B exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGA,B hydrolyzes GTP (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGC,D exchanges GTP for GDP (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGC,D hydrolyzes GTP (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 binds RHEB:GTP (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPHA-mediated growth cone collapse (Bos taurus)
NGEF exchanges GTP for GDP on RHOA (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Bos taurus)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Bos taurus)
HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ephrin signaling (Bos taurus)
PAKs autophosphorylate (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAKs phosphorylate MLC (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Semaphorin interactions (Bos taurus)
Sema3A PAK dependent Axon repulsion (Bos taurus)
Activation of PAK by Rac1 (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of LIMK-1 by PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Hemostasis (Bos taurus)
Factors involved in megakaryocyte development and platelet production (Bos taurus)
Kinesins (Bos taurus)
Kinesins bind microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinesins move along microtubules consuming ATP (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
GTP [cytosol]
VAV2 Rho/Rac effectors:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 1 (Bos taurus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
Gi activation by P2Y purinoceptor 12 (Bos taurus)
GTP [cytosol]
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thromboxane signalling through TP receptor (Bos taurus)
G13 activation by TP receptor (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gq activation by TP receptor (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Bos taurus)
Thrombin-activated PARs activate G12/13 (Bos taurus)
GTP [cytosol]
Thrombin-activated PARs activate Gq (Bos taurus)
GTP [cytosol]
Thrombin-activated PAR:Gq (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Budding of COPII coated vesicle (Bos taurus)
COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Bos taurus)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Coat Assembly (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
MHC class II antigen presentation (Bos taurus)
Formation of COPII vesicle (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Fusion of COPII vesicle with Golgi complex (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Rap1 signalling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rap1 signal termination by Rap1GAPs (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of RAS in B cells (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Src phosphorylate WASP,N-WASP (Bos taurus)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ROS and RNS production in phagocytes (Bos taurus)
NOX2 generates superoxide anion from oxygen (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Bos taurus)
RAP1A exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
RAP1A:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Metabolism of nucleotides (Bos taurus)
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
GTP [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Bos taurus)
GCH1 reduces GTP to dihydroneopterin triphosphate (Bos taurus)
GTP [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Bos taurus)
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Bos taurus)
Mitochondrial Uncoupling (Bos taurus)
The proton buffering model (Bos taurus)
Protons are translocated from the intermembrane space to the matrix (Bos taurus)
Purine nucleotide [cytosol]
GTP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
GDP-fucose biosynthesis (Bos taurus)
FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Bos taurus)
GTP [cytosol]
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP recruits GBF1 to the ERGIC (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 binds RAB1:GTP (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Cargo concentration in the ER (Bos taurus)
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglycylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglycylated microtubule protofilament [cytosol] (Bos taurus)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglycyl alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
TTLLs polyglutamylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglutamylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglutamyl microtubule protofilament [cytosol] (Bos taurus)
Polyglutamyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglutamyl alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Translation (Bos taurus)
Eukaryotic Translation Elongation (Bos taurus)
Peptide chain elongation (Bos taurus)
GTP-binding activates eEF2 (Bos taurus)
GTP [cytosol]
eEF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
Formation of the ternary complex, and subsequently, the 43S complex (Bos taurus)
De novo formation of eIF2:GTP (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of the 43S pre-initiation complex (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
GABA receptor activation (Bos taurus)
GABA B receptor activation (Bos taurus)
Activation of GABAB receptors (Bos taurus)
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
Cargo trafficking to the periciliary membrane (Bos taurus)
BBSome-mediated cargo-targeting to cilium (Bos taurus)
ARL6:GTP and the BBSome bind ciliary cargo (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARL6:GTP and the BBSome target cargo to the primary cilium (Bos taurus)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VxPx cargo-targeting to cilium (Bos taurus)
ARF4:GTP binds VxPx-motifs of membrane proteins (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GBF1 stimulates nucleotide exchange on ARF4 (Bos taurus)
GTP [cytosol]
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Sensory Perception (Bos taurus)
Visual phototransduction (Bos taurus)
The phototransduction cascade (Bos taurus)
Inactivation, recovery and regulation of the phototransduction cascade (Bos taurus)
GUCYs converts GTP to cGMP (Bos taurus)
GTP [cytosol]
Signal Transduction (Bos taurus)
Death Receptor Signalling (Bos taurus)
p75 NTR receptor-mediated signalling (Bos taurus)
p75NTR regulates axonogenesis (Bos taurus)
Axonal growth inhibition (RHOA activation) (Bos taurus)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
Intrinsic nucleotide exchange on RAS (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAP2K and MAPK activation (Bos taurus)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dual mechanism MAPK inhibitors bind MAPKs (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Bos taurus)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
BRAP autoubiquitinates (Bos taurus)
p21 RAS:GTP:BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:ub-BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
BRAP binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:BRAP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PEBP1 binds activated RAF1 (Bos taurus)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PP2A dephosphorylates RAF1 (Bos taurus)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PP5 dephosphorylates RAF1 S338 (Bos taurus)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAF activation (Bos taurus)
"Activator" RAF:YWHAB dimer binds RAS:GTP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of RAF (Bos taurus)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Raf dimer inhibitors bind RAF heterodimers (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Bos taurus)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Bos taurus)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS:GTP binds PI3K (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP:PI3K [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAS:GTP binds RAL GDS proteins (Bos taurus)
S-Farn-Me-2xPalmS HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
S-Farn-Me_2xPalmS HRAS:GTP:RAL GDS proteins [plasma membrane] (Bos taurus)
S-Farn-Me-2xPalmS HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MTOR signalling (Bos taurus)
AKT1S1 (PRAS40) binds mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of active mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GTP loading by Rheb (Bos taurus)
GTP [cytosol]
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Rag dimer formation (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ragulator binds Rag dimers (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SLC38A9 binds Ragulator:Rag dimers (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 phosphorylates AKT1S1 (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1-mediated signalling (Bos taurus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (12/13) signalling events (Bos taurus)
G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GEFs activate RhoA,B,C (Bos taurus)
GTP [cytosol]
GEFs [cytosol] (Bos taurus)
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
LARG activation by G alpha 12/13 (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (12/13):LARG [plasma membrane] (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Bos taurus)
GTP [cytosol]
p115-RhoGEF activation of RHOA (Bos taurus)
GTP [cytosol]
G13-activated p115-RhoGEF [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i) signalling events (Bos taurus)
Active G alpha (i)–i1/i2/i3 binds RGS proteins (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i):GTP:RGS [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Bos taurus)
G alpha (i):GTP:RGS [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i):GTP:SRC-1 [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i):GTP:p-Y416-SRC [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha (i):GTP:p-Y416-SRC [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Opioid Signalling (Bos taurus)
G-protein activation (Bos taurus)
G-protein alpha subunit is inactivated (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein mediated events (Bos taurus)
Adenylate cyclase activating pathway (Bos taurus)
Adenylate cyclase converts ATP into cyclic AMP (Bos taurus)
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Galpha-olf:GTP binds to adenylate cyclase and activates it (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC beta mediated events (Bos taurus)
Inactivation of PLC beta (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PIP2 hydrolysis (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Opsins act as GEFs for G alpha-t (Bos taurus)
GTP [cytosol]
G-alpha(t):GTP:G-beta-gamma:Opsins [plasma membrane] (Bos taurus)
G-alpha(t)-GTP:G-beta-gamma [plasma membrane] (Bos taurus)
G-alpha(t)-GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) signalling events (Bos taurus)
Active G alpha (q) binds RGS proteins (Bos taurus)
G alpha (q):GTP:RGS [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) binds to Trio family RhoGEFs (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (q) in G (q):RGS complex is inactivated (Bos taurus)
G alpha (q):GTP:RGS [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Bos taurus)
EGFR Transactivation by Gastrin (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
GTP [cytosol]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC-beta hydrolyses PIP2 to DAG and IP3 (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC-beta:G-alpha(q/11):DAG:IP3 [plasma membrane] (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
PLC-beta:G-alpha(q/11):PIP2 [plasma membrane] (Bos taurus)
Activated PLC beta 1/4 [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (z) signalling events (Bos taurus)
Active G alpha (z) binds RGS proteins (Bos taurus)
G alpha (z):GTP:RGS16,17,20 [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (z) in G alpha (z):RGS complex is inactivated (Bos taurus)
G alpha (z):GTP:RGS16,17,20 [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (z) inhibits adenylate cyclase (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (z):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)
GTP [cytosol]
ADRA2A-C:Catecholamine:Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gz (active) [plasma membrane] (Bos taurus)
G-protein alpha (z):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Hedgehog (Bos taurus)
Hedgehog 'off' state (Bos taurus)
KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
alpha tubulin:GTP [axonemal microtubule] (Bos taurus)
GTP [cytosol]
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
alpha tubulin:GTP [axonemal microtubule] (Bos taurus)
GTP [cytosol]
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
alpha tubulin:GTP [axonemal microtubule] (Bos taurus)
GTP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Bos taurus)
Signaling by PTK6 (Bos taurus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Bos taurus)
ARHGAP35 binds RHOA:GTP (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARHGAP35 stimulates RHOA GTPase activity (Bos taurus)
p-Y1105-ARHGAP35:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
GRB2 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by ERBB2 (Bos taurus)
ERBB2 Regulates Cell Motility (Bos taurus)
MEMO1 binds RHOA:GTP:DIAPH1 (Bos taurus)
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2 events in ERBB2 signaling (Bos taurus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by ERBB4 (Bos taurus)
SHC1 events in ERBB4 signaling (Bos taurus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Downstream signaling of activated FGFR1 (Bos taurus)
FRS-mediated FGFR1 signaling (Bos taurus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR1 (Bos taurus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR2 (Bos taurus)
Downstream signaling of activated FGFR2 (Bos taurus)
FRS-mediated FGFR2 signaling (Bos taurus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR2 (Bos taurus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
FRS-mediated FGFR3 signaling (Bos taurus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR3 (Bos taurus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
ARMS-mediated activation (Bos taurus)
C3G stimulates nucleotide exchange on Rap1 (Bos taurus)
GTP [cytosol]
Rap1-GTP [cytosol] (Bos taurus)
GTP [cytosol]
Frs2-mediated activation (Bos taurus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Bos taurus)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)
RAP1:GTP:B-Raf complex [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Bos taurus)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Bos taurus)
RAP1:GTP:activated BRAF dimer [endosome membrane] (Bos taurus)
RAP1:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
Signalling to RAS (Bos taurus)
p38MAPK events (Bos taurus)
Ral-GDS binds to Ras-GTP (Bos taurus)
Ras-GTP:RalGDS complex [plasma membrane] (Bos taurus)
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by SCF-KIT (Bos taurus)
Activation of RAS by p-KIT bound SOS1 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
Activated FMNL3 binds G-actin (Bos taurus)
RHOC:GTP:FMNL3 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:FMNL3:G-actin [plasma membrane] (Bos taurus)
RHOC:GTP:FMNL3 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
DAAM1 recruits GTP-bound RHOA (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
ppDVL:DAAM1:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
DIAPH1 binds RHOA:GTP (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FMNL2 binds RHOC:GTP (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:FMNL2 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FMNL3 binds RHOC:GTP (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:FMNL3 [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Bos taurus)
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] (Bos taurus)
RHOA:GTP:DIAPH1 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP recruits DAIPH2-3 to endosomes (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:DIAPH2-3 [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Bos taurus)
RHOD:GTP:DIAPH2-3 [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:DIAPH2:SRC-1 [endosome membrane] (Bos taurus)
RHOD:GTP:DIAPH2-3 [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Bos taurus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Bos taurus)
RAC1:GTP:FMNL1 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases Activate NADPH Oxidases (Bos taurus)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)
NOX3 complex:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
NOX2 complex:S100A8:S100A9:Ca2+ [phagocytic vesicle membrane] (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP binds NOX2 complex (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases Activate Rhotekin and Rhophilins (Bos taurus)
RHOA:GTP binds RHPN1 or RHPN2 (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RHPN1,RHPN2 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Bos taurus)
Src phosphorylate WASP,N-WASP (Bos taurus)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases activate CIT (Bos taurus)
Activated CIT binds KIF14 and PRC1 (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:CIT:KIF14:PRC1 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CIT-3 binds DLG4 (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3:DLG4 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:CIT-3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHO GTPases activate KTN1 (Bos taurus)
Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOG,RAC1,CDC42:GTP:KTN1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
KTN1 binds Kinesin-1 (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP:KTN1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA,RHOG,RAC1,CDC42:GTP:KTN1:Kinesin-1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP:KTN1 [endoplasmic reticulum membrane] (Bos taurus)
RHOA,RHOG,RAC1,CDC42:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHO GTPase cycle (Bos taurus)
RAC2 GTPase cycle (Bos taurus)
RAC2 GAPs stimulate RAC2 GTPase activity (Bos taurus)
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 GEFs activate RAC2 (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 binds effectors at the ER membrane (Bos taurus)
RAC2:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP:RAC2 endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RAC2:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC2 binds effectors at the phagocytic vesicle membrane (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2 binds effectors at the plasma membrane (Bos taurus)
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Bos taurus)
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 translocates to the ER membrane (Bos taurus)
RAC2:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 translocates to the mitochondrial membrane (Bos taurus)
RAC2:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC2 translocates to the phagocytic vesicle membrane (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
RAC2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3 GTPase cycle (Bos taurus)
RAC3 GAPs stimulate RAC3 GTPase activity (Bos taurus)
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3 GEFs activate RAC3 (Bos taurus)
GTP [cytosol]
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC3 binds ER effectors (Bos taurus)
RAC3:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC3:GTP:RAC3 endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RAC3:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC3 translocates to the endoplasmic reticulum membrane (Bos taurus)
RAC3:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RAC3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA GTPase cycle (Bos taurus)
RHOA GAPs stimulate RHOA GTPase activity (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA GEFs activate RHOA (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA binds effectors at the ER membrane (Bos taurus)
RHOA:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:RHOA endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RHOA:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA binds effectors at the plasma membrane (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP translocates to the ER membrane (Bos taurus)
RHOA:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC GTPase cycle (Bos taurus)
RHOC GAPs stimulate RHOC GTPase activity (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC GEFs activate RHOC (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC binds effectors at the plasma membrane (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP:RHOC effectors [plasma membrane] (Bos taurus)
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOC translocates to the endoplasmic reticulum membrane (Bos taurus)
RHOC:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOC:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD GTPase cycle (Bos taurus)
RHOD GAPs stimulate RHOD GTPase activity (Bos taurus)
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD auto-activates (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the Golgi membrane (Bos taurus)
RHOD:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD Golgi membrane effectors [Golgi membrane] (Bos taurus)
RHOD:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the endosome membrane (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD endosome effectors [endosome membrane] (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the mitochondrial outer membrane (Bos taurus)
RHOD:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD mitochondrial outer membrane effectors [mitochondrial outer membrane] (Bos taurus)
RHOD:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOD binds effectors at the plasma membrane (Bos taurus)
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP:RHOD plasma membrane effectors [plasma membrane] (Bos taurus)
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD translocates to the Golgi membrane (Bos taurus)
RHOD:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD translocates to the mitochondrial outer membrane (Bos taurus)
RHOD:GTP [mitochondrial outer membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP translocates to the endosome membrane (Bos taurus)
RHOD:GTP [endosome membrane] (Bos taurus)
GTP [cytosol]
RHOD:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF GTPase cycle (Bos taurus)
RHOF GAPs stimulate RHOF GTPase activity (Bos taurus)
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF auto-activates (Bos taurus)
GTP [cytosol]
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF binds effectors at the plasma membrane (Bos taurus)
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOF:GTP:RHOF effectors [plasma membrane] (Bos taurus)
RHOF:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG GTPase cycle (Bos taurus)
RHOG GAPs stimulate RHOG GTPase activity (Bos taurus)
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG GEFs activate RHOG (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG binds effectors at the ER membrane (Bos taurus)
RHOG:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP:RHOG endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Bos taurus)
RHOG:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOG binds effectors at the plasma membrane (Bos taurus)
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Bos taurus)
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOG translocates to the ER membrane (Bos taurus)
RHOG:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
RHOG:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOJ GTPase cycle (Bos taurus)
RHOJ GAPs stimulate RHOJ GTPase activity (Bos taurus)
RHOJ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOJ GEFs activate RHOJ (Bos taurus)
GTP [cytosol]
RHOJ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ GTPase cycle (Bos taurus)
RHOQ GAPs stimulate RHOQ GTPase activity (Bos taurus)
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ binds effectors at the plasma membrane (Bos taurus)
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ:GTP:RHOQ effectors [plasma membrane] (Bos taurus)
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOQ translocates to the Golgi-associated vesicle membranes (Bos taurus)
RHOQ:GTP [Golgi-associated vesicle membrane] (Bos taurus)
GTP [cytosol]
RHOQ:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOU GTPase cycle (Bos taurus)
RHOU auto-activates (Bos taurus)
GTP [cytosol]
RHOU:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOU binds effectors at the plasma membrane (Bos taurus)
RHOU:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOU:GTP:RHOU effectors [plasma membrane] (Bos taurus)
RHOU:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND2 GTPase cycle (Bos taurus)
RND2 binds GTP (Bos taurus)
GTP [cytosol]
RND2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND2 binds effectors (Bos taurus)
RND2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND2:GTP:RND2 effectors [plasma membrane] (Bos taurus)
RND2:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND3 GTPase cycle (Bos taurus)
RND3 binds GTP (Bos taurus)
GTP [cytosol]
RND3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND3 binds effectors (Bos taurus)
RND3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RND3:GTP:RND3 effectors [plasma membrane] (Bos taurus)
RND3:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by WNT (Bos taurus)
Beta-catenin independent WNT signaling (Bos taurus)
PCP/CE pathway (Bos taurus)
DAAM1 recruits GTP-bound RHOA (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
ppDVL:DAAM1:RHOA:GTP [cytosol] (Bos taurus)
RHOA:GTP:Mg2+ [cytosol] (Bos taurus)
GTP [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
ARL2:GTP binds ARL2BP (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARL2:GTP:ARL2BP [cytosol] (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Bos taurus)
ARL2:GTP:ARL2BP [cytosol] (Bos taurus)
ARL2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP recruits GBF1 to the ERGIC (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
![GTP [cytosol] icon](/icon/R-ICO-012805.svg){kind=icon}