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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
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Analysis Data
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Species Comparison
Tissue Distribution
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GTP [cytosol]
Stable Identifier
R-ALL-29438
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Guanosine 5'-triphosphate, GTP)(4-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Active MTORC1 binds the ULK1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Active MTORC1 phosphorylates ULK1 (Bos taurus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1 dissociates from ULK complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Selective autophagy (Bos taurus)
Aggrephagy (Bos taurus)
Aggresome dissociates from dynein and microtubule (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
RAN stimulates fusion of nuclear envelope (NE) membranes (Bos taurus)
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAN:GTP recruits nuclear envelope (NE) membranes (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAN:GTP:Nuclear envelope vesicles [nuclear envelope] (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)
GTP [cytosol]
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 binds to microtubules (Bos taurus)
EML4 homotrimer:Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinetochore capture of astral microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Recruitment of NuMA to mitotic centrosomes (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Mitotic Prophase (Bos taurus)
Golgi Cisternae Pericentriolar Stack Reorganization (Bos taurus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Bos taurus)
GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Bos taurus)
RAB2A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
p-T222,225-GORASP2:BLZF1:RAB2A:GTP [Golgi membrane] (Bos taurus)
RAB2A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
PLK1 phosphorylates GORASP1 (Bos taurus)
p-T216,S189,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
p-RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP:p-T210-PLK1 [Golgi membrane] (Bos taurus)
p-T216,S274,S373-GORASP1:p-S37-GOLGA2:p-RAB1:GTP [Golgi membrane] (Bos taurus)
p-RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
PLK1 phosphorylates OPTN (Bos taurus)
OPTN:RAB8A:GTP [Golgi membrane] (Bos taurus)
RAB8A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GTSE1 binds microtubule lattice in interphase cells (Bos taurus)
GTSE1:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to starvation (Bos taurus)
Amino acids regulate mTORC1 (Bos taurus)
RRAGA,B exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGA,B hydrolyzes GTP (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGC,D exchanges GTP for GDP (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGC,D hydrolyzes GTP (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGC,D:GTP [cytosol] (Bos taurus)
RRAGC:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGD:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1 binds RHEB:GTP (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Developmental Biology (Bos taurus)
Myogenesis (Bos taurus)
Nuclear translocation of p38 MAPK (Bos taurus)
ABL1:JLP:CDO complex [plasma membrane] (Bos taurus)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Bos taurus)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Bos taurus)
ABL1:JLP:CDO complex [plasma membrane] (Bos taurus)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Bos taurus)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH-ephrin mediated repulsion of cells (Bos taurus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHA-mediated growth cone collapse (Bos taurus)
NGEF exchanges GTP for GDP on RHOA (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
CDC42 and PIP2 bind WASL, activating it (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
N-WASP binds ARP2/3 and G-actin (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Bos taurus)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1 autophosphorylates (Bos taurus)
RAC1-GTP:p-S144,T423-PAK1 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1 binds RAC1:GTP (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP:PAK1 dimer:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP binds ROCK, activating it (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA:GTP:ROCK1,ROCK2 [plasma membrane] (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ras:GTP binds p120-RasGAP (Bos taurus)
HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Bos taurus)
HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Bos taurus)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Bos taurus)
HRAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)
GTP [cytosol]
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Ephrin signaling (Bos taurus)
PAK binds RAC and bPIX (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAKs autophosphorylate (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAKs phosphorylate MLC (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Bos taurus)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
bPIX exchanges GTP for GDP on RAC, activating it (Bos taurus)
GTP [cytosol]
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
L1CAM interactions (Bos taurus)
Recycling pathway of L1 (Bos taurus)
Formation of clathrin coated vesicle (Bos taurus)
GTP [cytosol]
Signal transduction by L1 (Bos taurus)
Activation of Rac1 by VAV2 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Interaction of PAK1 with Rac1-GTP (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
pPAK1:Rac1-GTP [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Netrin-1 signaling (Bos taurus)
DCC mediated attractive signaling (Bos taurus)
Activation of Cdc42 (Bos taurus)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rac1 (Bos taurus)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment and activation of N-WASP by Cdc42 (Bos taurus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] (Bos taurus)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
DSCAM interactions (Bos taurus)
Activation of JNK by DSCAM (Bos taurus)
DSCAM:p-S144-PAK1:RAC1:GTP [plasma membrane] (Bos taurus)
p-S144-PAK1:RAC1:GTP [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of p38MAPK by DSCAM (Bos taurus)
DSCAM:p-S144-PAK1:RAC1:GTP [plasma membrane] (Bos taurus)
p-S144-PAK1:RAC1:GTP [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
DSCAM associates with Rac1-GTP:pPAK1 (Bos taurus)
DSCAM:p-S144-PAK1:RAC1:GTP [plasma membrane] (Bos taurus)
p-S144-PAK1:RAC1:GTP [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-S144-PAK1:RAC1:GTP [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Semaphorin interactions (Bos taurus)
Sema3A PAK dependent Axon repulsion (Bos taurus)
Activation of PAK by Rac1 (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of LIMK-1 by PAK (Bos taurus)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Bos taurus)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema4D in semaphorin signaling (Bos taurus)
Sema4D induced cell migration and growth-cone collapse (Bos taurus)
Activation of Rho by LARG and PDZ-RhoGEF (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ROCK activation by RHO (Bos taurus)
Activated ROCK:RhoA/B/C:GTP [plasma membrane] (Bos taurus)
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RHOA/B/C:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Bos taurus)
Active Rac1 interacts with Plexin-B1:Sema4D (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Sema4D:pPlexin-B1:Met:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Bos taurus)
R-Ras-GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Inactivation of Rho-GTP by p190RhoGAP (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Bos taurus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rnd1 interacts with Plexin-B1:Sema4D (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p190RhoGAP binds Plexin-B1 (Bos taurus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP:ARHGAP35 [plasma membrane] (Bos taurus)
SEMA4D:MET:p-Y-PLXNB1:RND1:GTP [plasma membrane] (Bos taurus)
RND1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by ROBO receptors (Bos taurus)
SLIT2:ROBO1 increases RHOA activity (Bos taurus)
MYO9B inactivates RHOA (Bos taurus)
RHOA:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gene expression (Transcription) (Bos taurus)
Gene Silencing by RNA (Bos taurus)
Transcriptional regulation by small RNAs (Bos taurus)
Importin-8 imports AGO2:miRNA into the nucleus (Bos taurus)
RAN:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
RHEB:GTP [lysosomal membrane] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGA, RRAGB:GTP [cytosol] (Bos taurus)
RRAGA:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RRAGB:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
Tie2 Signaling (Bos taurus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Factors involved in megakaryocyte development and platelet production (Bos taurus)
Kinesins (Bos taurus)
Kinesins bind microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinesins move along microtubules consuming ATP (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
VAV1 is a GEF for Rho/Rac family GTPases (Bos taurus)
GTP [cytosol]
VAV1 Rho/Rac effectors:GTP [cytosol] (Bos taurus)
GTP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
GTP [cytosol]
VAV2 Rho/Rac effectors:GTP [cytosol] (Bos taurus)
GTP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Bos taurus)
GTP [cytosol]
VAV3 Rho/Rac effectors:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Activated integrin alphaIIb beta3 binds SHC1 (Bos taurus)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Talin (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PTK2 at Y397 (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Clustering of Integrin alphaIIb beta3 complexes (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dephosphorylation of inactive SRC by PTPB1 (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2:SOS provides linkage to MAPK signaling for Integrins (Bos taurus)
Interaction of SOS with GRB2 bound to FADK1 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of GRB2 to p-PTK2 (Bos taurus)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3 activation (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Interaction of integrin alphaIIb beta3 with Fibrinogen (Bos taurus)
Focal complex [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of pPTK2 by SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Release of CSK from SRC (Bos taurus)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SHC1 dissociates from integrin alphaIIb beta3 (Bos taurus)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Bos taurus)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SYK activation by SRC (Bos taurus)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SYK binds to integrin alphaIIb beta3 (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Translocation of PTK2 to Focal complexes (Bos taurus)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Translocation of RIAM to plasma membrane (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Crk binding to p130cas (Bos taurus)
CRK:p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of BCAR1 to PTK2 complex (Bos taurus)
BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Bos taurus)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Bos taurus)
Talin:RIAM complex [plasma membrane] (Bos taurus)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 1 (Bos taurus)
Dissociation of the P2Y purinoceptor 1:Gq complex (Bos taurus)
ADP:P2RY1:G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
Dissociation of the P2Y purinoceptor 12:Gi complex (Bos taurus)
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gi activation by P2Y purinoceptor 12 (Bos taurus)
GTP [cytosol]
ADP:P2RY12:G-protein Gi (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thromboxane signalling through TP receptor (Bos taurus)
Dissociation of the TP:G13 complex (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Dissociation of the TP:Gq complex (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
G13 activation by TP receptor (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gq activation by TP receptor (Bos taurus)
GTP [cytosol]
TP receptor:Thromboxane A2:G-protein Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Bos taurus)
Thrombin-activated PARs activate G12/13 (Bos taurus)
GTP [cytosol]
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Bos taurus)
G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PARs activate Gq (Bos taurus)
GTP [cytosol]
Thrombin-activated PAR:Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PARs:G12/13 (active) dissociate (Bos taurus)
G-protein alpha (12/13):GTP [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin activated PAR:G12/13 (active) [plasma membrane] (Bos taurus)
G-protein G12/G13 (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein G12 (active) [plasma membrane] (Bos taurus)
G-protein alpha (12):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Heterotrimeric G-protein G13 (active) [plasma membrane] (Bos taurus)
G-protein alpha (13):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PARs:Gq (active) dissociate (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Thrombin-activated PAR:Gq (active) [plasma membrane] (Bos taurus)
G protein-GTP [plasma membrane] (Bos taurus)
G protein alpha:GTP complex [plasma membrane] (Bos taurus)
GTP [cytosol]
Platelet homeostasis (Bos taurus)
Prostacyclin signalling through prostacyclin receptor (Bos taurus)
Gs activation by prostacyclin receptor (Bos taurus)
GTP [cytosol]
Prostacyclin:prostacyclin receptor:G-protein Gs (active) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (active) [plasma membrane] (Bos taurus)
G alpha (s):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Budding of COPII coated vesicle (Bos taurus)
COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Bos taurus)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Coat Assembly (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Disassembly of COPII coated vesicle (Bos taurus)
GTP [cytosol]
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Bos taurus)
COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Bos taurus)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Costimulation by the CD28 family (Bos taurus)
CD28 co-stimulation (Bos taurus)
CD28 dependent Vav1 pathway (Bos taurus)
Activation of Cdc42 by pVav1 (Bos taurus)
GTP [cytosol]
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of PAKs by RAC1 and CDC42 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rac1 by pVav1 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
MHC class II antigen presentation (Bos taurus)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Bos taurus)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Bos taurus)
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Formation of COPII vesicle (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Fusion of COPII vesicle with Golgi complex (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nonameric complex in COPII vesicle [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Internalization of MHC II:Ii clathrin coated vesicle (Bos taurus)
GTP [cytosol]
TGN-lysosomal vesicle coat assembly (Bos taurus)
AP-1 Complex:Arf1-GTP:Clathrin Triskelion:Nonameric complex [trans-Golgi network membrane] (Bos taurus)
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Arf1-GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Bos taurus)
GTP [cytosol]
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Kinesins:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Rap1 signalling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GTP [cytosol]
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Rap1 signal termination by Rap1GAPs (Bos taurus)
RAP1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of RAS in B cells (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
Activation of RAC1 by VAV2/3 (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
Activation of RAC1 by VAV (Bos taurus)
GTP [cytosol]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Recruitment of PAK to the membrane by binding active RAC1 (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Bos taurus)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GTP [cytosol]
p21 RAS:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Bos taurus)
Mother filament:branching complex [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ABL phosphorylates WAVEs (Bos taurus)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Activation of RAC1 by VAV (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Autophosphorylation of PAK1 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Detachment of WASP/WAVE (Bos taurus)
Mother filament:branching complex [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Bos taurus)
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WAVE2, WASP, N-WASP [plasma membrane] (Bos taurus)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1 and CDC42 activate PAK1 (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Bos taurus)
CDC42:GTP, RAC1:GTP [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Src phosphorylate WASP,N-WASP (Bos taurus)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Bos taurus)
CDC42:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Bos taurus)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Bos taurus)
RAC1:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ROS and RNS production in phagocytes (Bos taurus)
NOX2 generates superoxide anion from oxygen (Bos taurus)
NOX2 complex:RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
RAC2:GTP [phagocytic vesicle membrane] (Bos taurus)
GTP [cytosol]
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Acetylcholine regulates insulin secretion (Bos taurus)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Bos taurus)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Bos taurus)
G-alpha(q) 11,14,15,Q:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
GTP [cytosol]
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Gi,Go Heterotrimeric G-protein complex dissociates (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Free fatty acids regulate insulin secretion (Bos taurus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)
Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Bos taurus)
PLC beta1,2,3:G-alpha(q):GTP [plasma membrane] (Bos taurus)
G-alpha(q) 11,14,15,Q:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
FFAR1:FFAR1 ligands activates Gq (Bos taurus)
GTP [cytosol]
G-alpha(q)11,14,15,Q:G-beta:G-gamma [plasma membrane] (Bos taurus)
G-alpha(q) 11,14,15,Q:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Bos taurus)
RAP1A exchanges GDP for GTP (Bos taurus)
GTP [cytosol]
RAP1A:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PCK1 phosphorylates OA to yield PEP (Bos taurus)
GTP [cytosol]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)
(d)NTP [cytosol]
GTP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Bos taurus)
(d)NTP [cytosol]
GTP [cytosol]
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
GTP [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Bos taurus)
GCH1 reduces GTP to dihydroneopterin triphosphate (Bos taurus)
GTP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Molybdenum cofactor biosynthesis (Bos taurus)
Cyclisation of GTP to precursor Z (Bos taurus)
GTP [cytosol]
The citric acid (TCA) cycle and respiratory electron transport (Bos taurus)
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Bos taurus)
Mitochondrial Uncoupling (Bos taurus)
The proton buffering model (Bos taurus)
Protons are translocated from the intermembrane space to the matrix (Bos taurus)
Purine nucleotide [cytosol]
GTP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
GDP-fucose biosynthesis (Bos taurus)
FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Bos taurus)
GTP [cytosol]
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ARFGAPs stimulate ARF GTPase activity (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
Active ARF recruits coatomer (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP recruits GBF1 to the ERGIC (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:GBF1:USO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Bos taurus)
RAB1:GTP:USO1:coatomer [transport vesicle] (Bos taurus)
RAB1:GTP:USO1 [transport vesicle] (Bos taurus)
RAB1:GTP [transport vesicle] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1:coatomer [Golgi membrane] (Bos taurus)
RAB1:GTP:USO1 [Golgi membrane] (Bos taurus)
RAB1:GTP [Golgi membrane] (Bos taurus)
GTP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
CSNK1D phosphorylates SEC23 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP [cytosol] (Bos taurus)
GTP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SEC31:SEC13 and v-SNARE recruitment (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 binds RAB1:GTP (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)
RAB1:GTP:TBC1D20 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
RAB1:GTP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
GTP [cytosol]
Vesicle budding (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Cargo concentration in the ER (Bos taurus)
Inner coat assembly and cargo binding (Bos taurus)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Bos taurus)
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
SAR1B:GTP [endoplasmic reticulum membrane] (Bos taurus)
GTP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglycylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglycylated microtubule protofilament [cytosol] (Bos taurus)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglycyl alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
TTLLs polyglutamylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglutamylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Polyglutamyl microtubule protofilament [cytosol] (Bos taurus)
Polyglutamyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglutamyl alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Translation (Bos taurus)
Eukaryotic Translation Elongation (Bos taurus)
Peptide chain elongation (Bos taurus)
GTP-binding activates eEF2 (Bos taurus)
GTP [cytosol]
eEF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Regeneration of eEF1A:GTP by eEF1B activity (Bos taurus)
GTP [cytosol]
eEF1A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Bos taurus)
Translation initiation complex formation (Bos taurus)
Formation of translation initiation complexes containing mRNA that does not circularize (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of the ternary complex, and subsequently, the 43S complex (Bos taurus)
De novo formation of eIF2:GTP (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Formation of the 43S pre-initiation complex (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GTP hydrolysis and joining of the 60S ribosomal subunit (Bos taurus)
The 60S subunit joins the translation initiation complex (Bos taurus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Bos taurus)
eIF5B:GTP [cytosol] (Bos taurus)
GTP [cytosol]
eIF5B:GTP [cytosol] (Bos taurus)
GTP [cytosol]
eIF5B:GTP is hydrolyzed and released (Bos taurus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Bos taurus)
eIF5B:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Recycling of eIF2:GDP (Bos taurus)
eIF2 activation (Bos taurus)
GTP [cytosol]
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Ribosomal scanning and start codon recognition (Bos taurus)
Ribosomal scanning (Bos taurus)
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Start codon recognition (Bos taurus)
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
L13a-mediated translational silencing of Ceruloplasmin expression (Bos taurus)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
ternary complex [cytosol] (Bos taurus)
eIF2:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Eukaryotic Translation Termination (Bos taurus)
N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Bos taurus)
ETF1 dimer:eRF3:GTP [cytosol] (Bos taurus)
eRF3:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Me-Q185-ETF1 dimer:eRF3:GTP [cytosol] (Bos taurus)
eRF3:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
GABA receptor activation (Bos taurus)
GABA B receptor activation (Bos taurus)
Activation of GABAB receptors (Bos taurus)
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GTP) [plasma membrane] (Bos taurus)
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G alpha-olf:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] (Bos taurus)
G alpha (i): GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
ATAT acetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
alpha-tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
acetylated microtubule [cytosol] (Bos taurus)
acetylated microtubule protofilament [cytosol] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Bos taurus)
Ac K40 alpha tubulin:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Anchoring of the basal body to the plasma membrane (Bos taurus)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Bos taurus)
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Bos taurus)
RAB3IP:RAB11A:GTP:Golgi-derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:Golgi derived vesicle [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cargo trafficking to the periciliary membrane (Bos taurus)
BBSome-mediated cargo-targeting to cilium (Bos taurus)
ARL6:GTP and the BBSome bind ciliary cargo (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
ARL6:GTP and the BBSome target cargo to the primary cilium (Bos taurus)
ARL6:GTP:BBSome:ciliary cargo [plasma membrane] (Bos taurus)
ARL6:GTP [plasma membrane] (Bos taurus)
GTP [cytosol]
VxPx cargo-targeting to cilium (Bos taurus)
ARF4:GTP binds VxPx-motifs of membrane proteins (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex (Bos taurus)
ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
ASAP1 stimulates GTPase activity of ARF4 (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ASAP1 dimer: ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
ARF4:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
Cargo-carrying vesicles bud from the TGN (Bos taurus)
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP:RAB3IP:RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP:RAB11FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi-associated vesicle membrane] (Bos taurus)
RAB11A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
RAB8A:GTP [cytosol] (Bos taurus)
GTP [cytosol]
GBF1 stimulates nucleotide exchange on ARF4 (Bos taurus)
![GTP [cytosol] icon](/icon/R-ICO-012805.svg){kind=icon}