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CDC42:GTP [plasma membrane]
Stable Identifier
R-HSA-182921
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
CDC42-GTP
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Myogenesis (Homo sapiens)
Activation of p38 alpha/beta MAPK (Homo sapiens)
p38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Interaction of ABL1 with CDO complex (Homo sapiens)
ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Interaction of Bnip-2 with Cdc42 (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Interaction of p38 MAPK with JLP (Homo sapiens)
ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
p38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
JLP interacts with CDO complex (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Nuclear translocation of p38 MAPK (Homo sapiens)
ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
pp38 alpha/beta/gamma:ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
ABL1:JLP:CDO complex [plasma membrane] (Homo sapiens)
Cadherin-catenin:JLP:CDO:BOC:Bnip2-Cdc42 [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPHB-mediated forward signaling (Homo sapiens)
CDC42 and PIP2 bind WASL, activating it (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
ITSN1 exchanges GTP for GDP on CDC42, activating it (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
N-WASP binds ARP2/3 and G-actin (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Netrin-1 signaling (Homo sapiens)
DCC mediated attractive signaling (Homo sapiens)
Activation of Cdc42 (Homo sapiens)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Recruitment and activation of N-WASP by Cdc42 (Homo sapiens)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP:WASL:PIP2 [plasma membrane] (Homo sapiens)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Inactivation of CDC42 and RAC1 (Homo sapiens)
Inactivation of CDC42 (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Activation of WASP and N-WASP by CDC42 (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
An unknown GEF exchanges GTP for GDP on CDC42:GDP (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Src phosphorylate WASP,N-WASP (Homo sapiens)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WIP binds WASP,N-WASP, activating them (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Costimulation by the CD28 family (Homo sapiens)
CD28 co-stimulation (Homo sapiens)
CD28 dependent Vav1 pathway (Homo sapiens)
Activation of Cdc42 by pVav1 (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Activation of PAKs by RAC1 and CDC42 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Activation of WASP and N-WASP by CDC42 (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
An unknown GEF exchanges GTP for GDP on CDC42:GDP (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Autophosphorylation of PAK1 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1 and CDC42 activate PAK1 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Src phosphorylate WASP,N-WASP (Homo sapiens)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WIP binds WASP,N-WASP, activating them (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK6/MAPK4 signaling (Homo sapiens)
Activation of PAKs by RAC1 and CDC42 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Autophosphorylation of PAK1,2,3 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G-protein beta:gamma signalling (Homo sapiens)
G beta:gamma signalling through CDC42 (Homo sapiens)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Homo sapiens)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by EGFR (Homo sapiens)
EGFR downregulation (Homo sapiens)
Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP binds CBL:Beta-Pix (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CBL:Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP [plasma membrane] (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 [plasma membrane] (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate Formins (Homo sapiens)
CDC42:GTP:FMNL2 binds Profilin:G-actin (Homo sapiens)
CDC42:FMNL2:Profilin:G-actin [plasma membrane] (Homo sapiens)
CDC42:GTP:FMNL2 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:FMNL2 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
FMNL1 binds CDC42:GTP (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:FMNL1 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
FMNL2 binds CDC42:GTP (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:FMNL2 [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RHO GTPases Activate WASPs and WAVEs (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Activation of WASP and N-WASP by CDC42 (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Src phosphorylate WASP,N-WASP (Homo sapiens)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
WIP binds WASP,N-WASP, activating them (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RHO GTPases activate IQGAPs (Homo sapiens)
GTP-bound RAC1 and CDC42 bind IQGAPs (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
IQGAP1 binds CLIP1 and microtubules (Homo sapiens)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAP1 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
IQGAPs bind CALM1 (Homo sapiens)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
IQGAPs bind F-actin, which is inhibited by calmodulin (Homo sapiens)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Homo sapiens)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RHO GTPases activate PAKs (Homo sapiens)
Autophosphorylation of PAK1,2,3 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1 and CDC42 activate PAK1 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1:GTP,CDC42:GTP:PAK1 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1 and CDC42 activate PAK2 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK2 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RAC1 and CDC42 activate PAK3 (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Homo sapiens)
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42 GEFs activate CDC42 (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
CDC42 translocates to the endoplasmic reticulum membrane (Homo sapiens)
CDC42:GTP [plasma membrane] (Homo sapiens)
Participants
components
CDC42 [plasma membrane]
(Homo sapiens)
GTP [cytosol]
Participates
as a component of
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Homo sapiens)
Cadherin-catenin:CDO:BOC:Bnip2:CDC42-GTP [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:Active PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
G-protein beta-gamma complex:PAK1:ARHGEF6:Active CDC42 [plasma membrane] (Homo sapiens)
CDC42:GTP:FMNL2 [plasma membrane] (Homo sapiens)
CDC42:GTP:FMNL1 [plasma membrane] (Homo sapiens)
Ub-Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
Beta-Pix:CDC42:GTP [cytosol] (Homo sapiens)
CDC42:GTP:WASP/N-WASP [plasma membrane] (Homo sapiens)
CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Homo sapiens)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane] (Homo sapiens)
as an input of
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42 translocates to the endoplasmic reticulum membrane (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
Inactivation of Cdc42 (Rattus norvegicus)
Inactivation of CDC42 (Homo sapiens)
Interaction of Bnip-2 with Cdc42 (Homo sapiens)
FMNL2 binds CDC42:GTP (Homo sapiens)
FMNL1 binds CDC42:GTP (Homo sapiens)
Activation of WASP and N-WASP by CDC42 (Homo sapiens)
CDC42:GTP binds PtdIns(4,5)P2:WASP,N-WASP (Homo sapiens)
as an output of
CDC42 GEFs activate CDC42 (Homo sapiens)
Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Homo sapiens)
An unknown GEF exchanges GTP for GDP on CDC42:GDP (Homo sapiens)
Activation of Cdc42 by pVav1 (Homo sapiens)
as a member of
CDC42:GTP, RAC1:GTP [plasma membrane] (Homo sapiens)
Inferred To
CDC42:GTP [plasma membrane]
(Bos taurus)
CDC42:GTP [plasma membrane]
(Caenorhabditis elegans)
CDC42:GTP [plasma membrane]
(Canis familiaris)
CDC42:GTP [plasma membrane]
(Danio rerio)
CDC42:GTP [plasma membrane]
(Dictyostelium discoideum)
CDC42:GTP [plasma membrane]
(Drosophila melanogaster)
CDC42:GTP [plasma membrane]
(Gallus gallus)
CDC42:GTP [plasma membrane]
(Rattus norvegicus)
CDC42:GTP [plasma membrane]
(Saccharomyces cerevisiae)
CDC42:GTP [plasma membrane]
(Schizosaccharomyces pombe)
CDC42:GTP [plasma membrane]
(Sus scrofa)
CDC42:GTP [plasma membrane]
(Xenopus tropicalis)
Cdc42:GTP [plasma membrane]
(Mus musculus)
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