GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13

Stable Identifier
R-HSA-9712201
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Olfactory receptors are associated with trimeric G protein complexes containing the GNAL (Golf, G alpha olf) alpha subunit, the GNB1 beta subunit, and the GNG13 gamma subunit. The binding of an odorant to an olfactory receptor causes the GNAL subunit to exchange GDP for GTP (Borgmann-Winter et al. 2016, and inferred from rat homologs). GNAL is a member of the Gs family of G alpha proteins.

Literature References
PubMed ID Title Journal Year
26373539 Altered G Protein Coupling in Olfactory Neuroepithelial Cells From Patients With Schizophrenia

Borgmann-Winter, KE, Wang, HY, Ray, R, Willis, BR, Moberg, PJ, Rawson, NE, Gur, RE, Turetsky, BI, Hahn, CG

Schizophr Bull 2016
Participants
Participates
Inferred From
Authored
Reviewed
Created
Cite Us!