GTP-binding activates eEF2

Stable Identifier
R-HSA-156930
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
GTP-binding activates eEF2
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
At the beginning of this reaction, 1 molecule of 'eEF2', and 1 molecule of 'GTP' are present. At the end of this reaction, 1 molecule of 'eEF2:GTP' is present.

This reaction takes place in the 'cytosol' (Guillot et al. 2013).
Literature References
PubMed ID Title Journal Year
8407925 GTP binding to elongation factor eEF-2 unmasks a tryptophan residue required for biological activity

Lavergne, JP, Sontag, B, Guillot, D, Reboud, JP, Di Pietro, A, Penin, F

J. Biol. Chem. 1993
Participants
Input
Output
Participates
as an event of
Orthologous Events
GTP-binding activates eEF2 (Bos taurus)
GTP-binding activates eEF2 (Caenorhabditis elegans)
GTP-binding activates eEF2 (Canis familiaris)
GTP-binding activates eEF2 (Danio rerio)
GTP-binding activates eEF2 (Dictyostelium discoideum)
GTP-binding activates eEF2 (Drosophila melanogaster)
GTP-binding activates eEF2 (Gallus gallus)
GTP-binding activates eEF2 (Mus musculus)
GTP-binding activates eEF2 (Plasmodium falciparum)
GTP-binding activates eEF2 (Rattus norvegicus)
GTP-binding activates eEF2 (Saccharomyces cerevisiae)
GTP-binding activates eEF2 (Schizosaccharomyces pombe)
GTP-binding activates eEF2 (Sus scrofa)
GTP-binding activates eEF2 (Xenopus tropicalis)
Created
Gopinathrao, G  (2004-12-14)
Cite Us!