Gq activation by P2Y purinoceptor 1

Stable Identifier
R-HSA-418579
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Gq activation by P2Y purinoceptor 1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The G-protein alpha subunit exchanges GDP for GTP

Literature References
PubMed ID Title Journal Year
14742685 Agonist binding and Gq-stimulating activities of the purified human P2Y1 receptor

Waldo, GL, Harden, TK

Mol Pharmacol 2004
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
guanyl-nucleotide exchange factor activity of ADP:P2RY1:G-protein Gq/11 (inactive) [plasma membrane]
Physical Entity
ADP:P2RY1:G-protein Gq/11 (inactive) [plasma membrane]
Activity
guanyl-nucleotide exchange factor activity (0005085)
Inferred From
Activated human P2Y purinoceptor 1 binds mouse G-protein Gq (Homo sapiens)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Poole, AW  (2009-11-02)
Jones, ML  (2009-11-02)
Harper, MT  (2009-11-02)
Created
Jupe, S  (2009-04-24)