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RAC1:GTP [plasma membrane]
Stable Identifier
R-DRE-442641
Type
Complex
Species
Danio rerio
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
EPH-Ephrin signaling (Danio rerio)
EPH-ephrin mediated repulsion of cells (Danio rerio)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
VAV exchanges GTP for GDP on RAC1, activating it (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Netrin-1 signaling (Danio rerio)
DCC mediated attractive signaling (Danio rerio)
Activation of Rac1 (Danio rerio)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Semaphorin interactions (Danio rerio)
Sema3A PAK dependent Axon repulsion (Danio rerio)
Activation of PAK by Rac1 (Danio rerio)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Danio rerio)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Autophosphorylation of PAK (Danio rerio)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Danio rerio)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Danio rerio)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Phosphorylation of LIMK-1 by PAK (Danio rerio)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Danio rerio)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Costimulation by the CD28 family (Danio rerio)
CD28 co-stimulation (Danio rerio)
CD28 dependent Vav1 pathway (Danio rerio)
Activation of PAKs by RAC1 and CDC42 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1,RAC2,RHOG activate PI3K (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP:PI3K alpha [plasma membrane] (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK6/MAPK4 signaling (Danio rerio)
Activation of PAKs by RAC1 and CDC42 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Autophosphorylation of PAK1,2,3 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Signaling by Non-Receptor Tyrosine Kinases (Danio rerio)
Signaling by PTK6 (Danio rerio)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Danio rerio)
Activation of RAC1 by the PXN:CRK complex (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Danio rerio)
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases Activate Formins (Danio rerio)
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Danio rerio)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
RAC1:GTP:FMNL1 [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
RAC1:GTP:FMNL1 [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Danio rerio)
RAC1:GTP:FMNL1 [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RHO GTPases Activate NADPH Oxidases (Danio rerio)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Danio rerio)
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
NOX1 complex:RAC1:GTP generates superoxide from oxygen (Danio rerio)
NOX1 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
NOX3 complex:RAC1:GTP generates superoxide from oxygen (Danio rerio)
NOX3 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP binds NOX1 complex (Danio rerio)
NOX1 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP binds NOX3 complex (Danio rerio)
NOX3 complex:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RHO GTPases activate IQGAPs (Danio rerio)
GTP-bound RAC1 and CDC42 bind IQGAPs (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
IQGAPs bind F-actin, which is inhibited by calmodulin (Danio rerio)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RHO GTPases activate PAKs (Danio rerio)
Autophosphorylation of PAK1,2,3 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1 and CDC42 activate PAK2 (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RHO GTPase cycle (Danio rerio)
RAC1 GTPase cycle (Danio rerio)
RAC1 GAPs stimulate RAC1 GTPase activity (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1 GEFs activate RAC1 (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
RAC1 translocates to the endoplasmic reticulum membrane (Danio rerio)
RAC1:GTP [plasma membrane] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GTP [cytosol]
rac1a [plasma membrane]
(Danio rerio)
Participates
as an input of
RAC1 translocates to the endoplasmic reticulum membrane (Danio rerio)
RAC1 GAPs stimulate RAC1 GTPase activity (Danio rerio)
RAC1:GTP binds NOX1 complex (Danio rerio)
RAC1:GTP binds NOX3 complex (Danio rerio)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Danio rerio)
as an output of
RAC1 GEFs activate RAC1 (Danio rerio)
VAV exchanges GTP for GDP on RAC1, activating it (Danio rerio)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Danio rerio)
Activation of RAC1 by the PXN:CRK complex (Danio rerio)
as a component of
NOX1 complex:RAC1:GTP [plasma membrane] (Danio rerio)
NOX3 complex:RAC1:GTP [plasma membrane] (Danio rerio)
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
Sema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTP [plasma membrane] (Danio rerio)
NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP:FMNL1 [plasma membrane] (Danio rerio)
as a member of
CDC42:GTP, RAC1:GTP [plasma membrane] (Danio rerio)
RAC1:GTP,RAC2:GTP,RHOG:GTP [plasma membrane] (Danio rerio)
Inferred From
RAC1:GTP [plasma membrane]
(Homo sapiens)
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