Reactome | G protein alpha:GTP complex [plasma membrane]

G protein alpha:GTP complex [plasma membrane]

Stable Identifier

R-SSC-167438

Type

Complex

Species

Sus scrofa

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

G-protein alpha (q/11/14/15) [plasma membrane] (Sus scrofa)
GTP [cytosol]

Participates

as an output of

Gq-BTK complex dissociates to Active BTK and Gq (Sus scrofa)
Dissociation of the TP:Gq complex (Sus scrofa)
The receptor:G-protein complex dissociates (Sus scrofa)
Thrombin-activated PARs:Gq (active) dissociate (Sus scrofa)
The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
Dissociation of the P2Y purinoceptor 1:Gq complex (Sus scrofa)

as an input of

Active Gq binds BTK (Sus scrofa)
G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Sus scrofa)
G alpha (q) binds to Trio family RhoGEFs (Sus scrofa)
GRK2 sequesters activated Gq (Sus scrofa)
Active G alpha (q) binds RGS proteins (Sus scrofa)
G alpha (q) inhibits PI3K alpha (Sus scrofa)
G-protein alpha subunit is inactivated (Sus scrofa)

as a component of

Active Gq:BTK [plasma membrane] (Sus scrofa)
G-protein alpha (q/11):Trio family RhoGEFs [plasma membrane] (Sus scrofa)
G-protein alpha (q):GRK2 [plasma membrane] (Sus scrofa)
G alpha (q):GTP:RGS [plasma membrane] (Sus scrofa)
G-protein alpha (q/11):PI3K alpha [plasma membrane] (Sus scrofa)
G protein-GTP [plasma membrane] (Sus scrofa)
Activated PLC beta 1/4 [plasma membrane] (Sus scrofa)

Inferred From

G-protein alpha (q/11): GTP [plasma membrane] (Homo sapiens)

G protein alpha:GTP complex [plasma membrane] (Homo sapiens)

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