G13 activation by TP receptor

Stable Identifier
R-HSA-428917
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
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G13 activation by TP receptor
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The G-protein alpha subunit exchanges GDP for GTP
Literature References
PubMed ID Title Journal Year
16418336 The G12 family of G proteins as a reporter of thromboxane A2 receptor activity

Zhang, L, DiLizio, C, Kim, D, Smyth, EM, Manning, DR

Mol Pharmacol 2006
Participants
Input
Output
Participates
as an event of
Catalyst Activity

guanyl-nucleotide exchange factor activity of TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane]

Physical Entity
TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Homo sapiens)
Activity
guanyl-nucleotide exchange factor activity (GO:0005085)
Orthologous Events
G13 activation by TP receptor (Bos taurus)
G13 activation by TP receptor (Caenorhabditis elegans)
G13 activation by TP receptor (Canis familiaris)
G13 activation by TP receptor (Danio rerio)
G13 activation by TP receptor (Drosophila melanogaster)
G13 activation by TP receptor (Gallus gallus)
G13 activation by TP receptor (Mus musculus)
G13 activation by TP receptor (Rattus norvegicus)
G13 activation by TP receptor (Sus scrofa)
G13 activation by TP receptor (Xenopus tropicalis)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Poole, AW  (2009-11-02)
Jones, ML  (2009-11-02)
Harper, MT  (2009-11-02)
Created
Jupe, S  (2009-07-13)
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