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eIF2:GTP [cytosol]
Stable Identifier
R-DME-72531
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Translation (Drosophila melanogaster)
Eukaryotic Translation Initiation (Drosophila melanogaster)
Cap-dependent Translation Initiation (Drosophila melanogaster)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Drosophila melanogaster)
Translation initiation complex formation (Drosophila melanogaster)
Formation of translation initiation complexes containing mRNA that does not circularize (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
Formation of the ternary complex, and subsequently, the 43S complex (Drosophila melanogaster)
De novo formation of eIF2:GTP (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
Formation of the 43S pre-initiation complex (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
Recycling of eIF2:GDP (Drosophila melanogaster)
eIF2 activation (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
Ribosomal scanning and start codon recognition (Drosophila melanogaster)
Ribosomal scanning (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
Start codon recognition (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
L13a-mediated translational silencing of Ceruloplasmin expression (Drosophila melanogaster)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
EIF2S1:EIF2S2:EIF2S3 [cytosol]
(Drosophila melanogaster)
GTP [cytosol]
Participates
as an input of
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Drosophila melanogaster)
as an output of
eIF2 activation (Drosophila melanogaster)
De novo formation of eIF2:GTP (Drosophila melanogaster)
as a component of
ternary complex [cytosol] (Drosophila melanogaster)
Inferred From
eIF2:GTP [cytosol]
(Homo sapiens)
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