AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP

Stable Identifier
R-HSA-432195
Type
Reaction
Species
Homo sapiens
Compartment
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The AVP:AVPR2 complex activates G-protein alpha s by causing a conformational change in G-protein alpha s that causes it to release GDP and bind GTP.

Literature References
PubMed ID Title Journal Year
10649434 Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate

Torrejón, M, Olate, J, Toro, MJ, Echeverria, V, Ropero, S, Hinrichs, MV, Martinez, J

J Cell Biochem 2000
11968001 S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate

Olate, J, Romo, X, Brito, M, Hinrichs, MV, Guzmán, L, Soto, X

J Cell Biochem 2002
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