AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP

Stable Identifier
R-HSA-432195
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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The AVP:AVPR2 complex activates G-protein alpha s by causing a conformational change in G-protein alpha s that causes it to release GDP and bind GTP.

Literature References
PubMed ID Title Journal Year
11968001 S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate

Brito, M, Guzmán, L, Romo, X, Soto, X, Hinrichs, MV, Olate, J

J Cell Biochem 2002
10649434 Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate

Echeverria, V, Hinrichs, MV, Torrejón, M, Ropero, S, Martinez, J, Toro, MJ, Olate, J

J Cell Biochem 2000
Participants
Participant Of
Orthologous Events
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Created