ITSN1 exchanges GTP for GDP on CDC42, activating it

Stable Identifier
R-HSA-3928632
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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General
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Activated intersectin 1 (ITSN1) activates CDC42 by exchanging GDP with GTP, resulting in high levels of CDC42:GTP in spines.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
guanyl-nucleotide exchange factor activity of p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created
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