ITSN1 exchanges GTP for GDP on CDC42, activating it

Stable Identifier
R-HSA-3928632
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Activated intersectin 1 (ITSN1) activates CDC42 by exchanging GDP with GTP, resulting in high levels of CDC42:GTP in spines.
Participants
Participates
Catalyst Activity

guanyl-nucleotide exchange factor activity of p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane]

Inferred From
Authored
Reviewed
Created
Cite Us!