SAR1-GDP is recruited to the ER membrane by the transmembrane GEF (Guanine nucleotide exchange factor) PREB (also known as SEC12), where it is converted to SAR1-GTP. PREB itself is recruited to ER exit sites through interaction with MIA2 (also known as CTAGE5).
Saito, K, Yamashiro, K, Shimazu, N, Tanabe, T, Kontani, K, Katada, T
Stephens, DJ, Lin-Marq, N, Pagano, A, Pepperkok, R, Paccaud, JP
Hammond, AT, Glick, BS
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