oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol]

Stable Identifier
R-GGA-372741
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol]
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PCK1, the cytosolic form of phosphoenolpyruvate carboxykinase, catalyzes the reaction of oxaloacetate and GTP to form phosphoenolpyruvate, GDP, and CO2. In the chicken, expression of PCK1 is confined to the kidney and is hormonally regulated (Hod et al. 1982; Cook et al. 1986).
Literature References
PubMed ID Title Journal Year
7142177 The mitochondrial and cytosolic forms of avian phosphoenolpyruvate carboxykinase (GTP) are encoded by different messenger RNAs

Hanson, RW, Utter, MF, Hod, Y

J Biol Chem 1982
3094011 Nucleotide sequence of the mRNA encoding the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) from the chicken

Hanson, RW, Cook, JS, Hod, Y, Weldon, SL, Garcia-Ruiz, JP

Proc Natl Acad Sci U S A 1986
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Catalyst Activity

phosphoenolpyruvate carboxykinase (GTP) activity of PCK1 [cytosol]

Physical Entity
PCK1 [cytosol] (Gallus gallus)
Activity
phosphoenolpyruvate carboxykinase (GTP) activity (GO:0004613)
Authored
D'Eustachio, P  (2008-09-10)
Reviewed
Harris, RA  (2008-09-10)
Created
D'Eustachio, P  (2008-06-28)
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