Reactome | RHOH binds GTP

RHOH binds GTP

Stable Identifier

R-HSA-9018756

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane, cytosol

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RHOH is an atypical RHO GTPase that constitutively binds to GTP. RHOH has impaired GTPase activity and does not hydrolyze GTP (Li et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
11809807	The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function Li, X, Bu, X, Lu, B, Avraham, H, Flavell, RA, Lim, B	Mol. Cell. Biol.	2002