Gs activation by prostacyclin receptor

Stable Identifier
R-HSA-392870
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
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Gs activation by prostacyclin receptor
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The G-protein alpha subunit exchanges GDP for GTP

Literature References
PubMed ID Title Journal Year
15980156 Can a GDP-liganded G-protein be active?

Wieland, T, Michel, MC

Mol Pharmacol 2005
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
guanyl-nucleotide exchange factor activity of Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
Physical Entity
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]
Activity
guanyl-nucleotide exchange factor activity (0005085)
Orthologous Events
Gs activation by prostacyclin receptor (Canis familiaris)
Gs activation by prostacyclin receptor (Danio rerio)
Gs activation by prostacyclin receptor (Drosophila melanogaster)
Gs activation by prostacyclin receptor (Mus musculus)
Gs activation by prostacyclin receptor (Rattus norvegicus)
Gs activation by prostacyclin receptor (Sus scrofa)
Gs activation by prostacyclin receptor (Xenopus tropicalis)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Kunapuli, SP  (2010-06-07)
Created
Jupe, S  (2009-03-09)