Gs activation by prostacyclin receptor

Stable Identifier
R-HSA-392870
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Gs activation by prostacyclin receptor
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The G-protein alpha subunit exchanges GDP for GTP
Literature References
PubMed ID Title Journal Year
15980156 Can a GDP-liganded G-protein be active?

Michel, MC, Wieland, T

Mol Pharmacol 2005
Participants
Input
Output
Participates
as an event of
Catalyst Activity

guanyl-nucleotide exchange factor activity of Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane]

Physical Entity
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Homo sapiens)
Activity
guanyl-nucleotide exchange factor activity (GO:0005085)
Orthologous Events
Gs activation by prostacyclin receptor (Bos taurus)
Gs activation by prostacyclin receptor (Canis familiaris)
Gs activation by prostacyclin receptor (Drosophila melanogaster)
Gs activation by prostacyclin receptor (Mus musculus)
Gs activation by prostacyclin receptor (Sus scrofa)
Gs activation by prostacyclin receptor (Xenopus tropicalis)
Authored
Akkerman, JW  (2009-06-03)
Reviewed
Kunapuli, SP  (2010-06-07)
Created
Jupe, S  (2009-03-09)
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