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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
DOIs
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ORCID Integration Project
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Docs
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How do I search ?
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p21 RAS:GTP [plasma membrane]
Stable Identifier
R-CFA-109783
Type
Complex
Species
Canis familiaris
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
NCAM signaling for neurite out-growth (Canis familiaris)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
Tie2 Signaling (Canis familiaris)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Downstream signaling events of B Cell Receptor (BCR) (Canis familiaris)
Activation of RAS in B cells (Canis familiaris)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CD209 (DC-SIGN) signaling (Canis familiaris)
PAK phosphorylates p21 RAF1 on S338 (Canis familiaris)
p21 RAS:GTP:RAF1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAF1 binds p21 RAS:GTP (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:RAF1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
SFKs phosphorylates RAF1 on Y340,Y341 (Canis familiaris)
p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
DAP12 interactions (Canis familiaris)
DAP12 signaling (Canis familiaris)
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated MAPK activation (Canis familiaris)
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
Intrinsic nucleotide exchange on RAS (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dissociation of RAS:RAF complex (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Canis familiaris)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Canis familiaris)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Negative regulation of MAPK pathway (Canis familiaris)
BRAP autoubiquitinates (Canis familiaris)
p21 RAS:GTP:BRAP [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
BRAP binds RAS:GTP (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:BRAP [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
PEBP1 binds activated RAF1 (Canis familiaris)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Canis familiaris)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
PP2A dephosphorylates RAF1 (Canis familiaris)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
PP5 dephosphorylates RAF1 S338 (Canis familiaris)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAF activation (Canis familiaris)
Phosphorylation of RAF (Canis familiaris)
p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Raf dimer inhibitors bind RAF heterodimers (Canis familiaris)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Canis familiaris)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAS:GTP binds PI3K (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:PI3K [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Regulation of RAS by GAPs (Canis familiaris)
RAS GAPs bind RAS:GTP (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAS GAPs stimulate RAS GTPase activity (Canis familiaris)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (q) signalling events (Canis familiaris)
Gastrin-CREB signalling pathway via PKC and MAPK (Canis familiaris)
EGFR Transactivation by Gastrin (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by Non-Receptor Tyrosine Kinases (Canis familiaris)
Signaling by PTK6 (Canis familiaris)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Canis familiaris)
RASA1 binds RAS:GTP (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:RASA1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RASA1 stimulates RAS GTPase activity (Canis familiaris)
p21 RAS:GTP:RASA1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Extra-nuclear estrogen signaling (Canis familiaris)
Estrogen-stimulated signaling through PRKCZ (Canis familiaris)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Canis familiaris)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Canis familiaris)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by EGFR (Canis familiaris)
GRB2 events in EGFR signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
SHC1 events in EGFR signaling (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by ERBB2 (Canis familiaris)
GRB2 events in ERBB2 signaling (Canis familiaris)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by ERBB4 (Canis familiaris)
SHC1 events in ERBB4 signaling (Canis familiaris)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by FGFR (Canis familiaris)
Signaling by FGFR1 (Canis familiaris)
Downstream signaling of activated FGFR1 (Canis familiaris)
FRS-mediated FGFR1 signaling (Canis familiaris)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
SHC-mediated cascade:FGFR1 (Canis familiaris)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by FGFR2 (Canis familiaris)
Downstream signaling of activated FGFR2 (Canis familiaris)
FRS-mediated FGFR2 signaling (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
SHC-mediated cascade:FGFR2 (Canis familiaris)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by FGFR3 (Canis familiaris)
Downstream signaling of activated FGFR3 (Canis familiaris)
FRS-mediated FGFR3 signaling (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
SHC-mediated cascade:FGFR3 (Canis familiaris)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by FGFR4 (Canis familiaris)
Downstream signaling of activated FGFR4 (Canis familiaris)
FRS-mediated FGFR4 signaling (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
SHC-mediated cascade:FGFR4 (Canis familiaris)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by MET (Canis familiaris)
MET activates RAS signaling (Canis familiaris)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Signalling to ERKs (Canis familiaris)
Signalling to RAS (Canis familiaris)
p38MAPK events (Canis familiaris)
Ral-GDS binds to Ras-GTP (Canis familiaris)
Ras-GTP:RalGDS complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by PDGF (Canis familiaris)
Downstream signal transduction (Canis familiaris)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by SCF-KIT (Canis familiaris)
Activation of RAS by p-KIT bound SOS1 (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
VEGFR2 mediated cell proliferation (Canis familiaris)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Canis familiaris)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP [plasma membrane] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GTP [cytosol]
mature p21 RAS [plasma membrane]
(Canis familiaris)
Participates
as a component of
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAFs:YWHAB dimer [plasma membrane] (Canis familiaris)
p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Canis familiaris)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Canis familiaris)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP:BRAP [plasma membrane] (Canis familiaris)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Canis familiaris)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21RAS:GTP:p-S621 RAF1 homo/heterodimer [plasma membrane] (Canis familiaris)
p21 RAS:GTP:RAS GAPs [plasma membrane] (Canis familiaris)
p21 RAS:GTP:PI3K [plasma membrane] (Canis familiaris)
p21 RAS:GTP:RASA1 [plasma membrane] (Canis familiaris)
Ras-GTP:RalGDS complex [plasma membrane] (Canis familiaris)
p21 RAS:GTP:RAF1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP:p-S338-RAF1 [plasma membrane] (Canis familiaris)
p21 RAS:GTP:p-S338,Y340,Y341-RAF1 [plasma membrane] (Canis familiaris)
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Canis familiaris)
as an input of
BRAP binds RAS:GTP (Canis familiaris)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Canis familiaris)
RAS GAPs bind RAS:GTP (Canis familiaris)
RAS:GTP binds PI3K (Canis familiaris)
RASA1 binds RAS:GTP (Canis familiaris)
Ral-GDS binds to Ras-GTP (Canis familiaris)
RAF1 binds p21 RAS:GTP (Canis familiaris)
as an output of
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Canis familiaris)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Canis familiaris)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Canis familiaris)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Canis familiaris)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Canis familiaris)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Canis familiaris)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Canis familiaris)
RAS GEFs promote RAS nucleotide exchange (Canis familiaris)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Canis familiaris)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Intrinsic nucleotide exchange on RAS (Canis familiaris)
Activation of RAS by p-KIT bound SOS1 (Canis familiaris)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Canis familiaris)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Canis familiaris)
SOS mediated nucleotide exchange of RAS (SHC) (Canis familiaris)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Canis familiaris)
Inferred From
p21 RAS:GTP [plasma membrane]
(Homo sapiens)
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