bPIX exchanges GTP for GDP on RAC, activating it

Stable Identifier
R-HSA-3928633
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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p-21-activated kinase (PAK) interacting exchange factor (beta-PIX, bPIX aka ARHGEF7) a Rac GEF localised at the dendritic spines, activates Rac by exchanging GDP for GTP.

Literature References
PubMed ID Title Journal Year
12695502 Synapse formation is regulated by the signaling adaptor GIT1

Zhang, H, Webb, DJ, Asmussen, H, Horwitz, AF

J. Cell Biol. 2003
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
guanyl-nucleotide exchange factor activity of EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created