Reactome | RHEB:GTP [lysosomal membrane]

RHEB:GTP [lysosomal membrane]

Stable Identifier

R-DRE-165189

Type

Complex

Species

Danio rerio

Compartment

lysosomal membrane

Locations in the PathwayBrowser

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Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - Generic Transcription Pathway (Danio rerio)
    - Transcriptional Regulation by TP53 (Danio rerio)
      - TP53 Regulates Metabolic Genes (Danio rerio)
        
        RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Danio rerio)
        
        Active mTORC1 complex [lysosomal membrane] (Danio rerio)
        
        RHEB:GTP [lysosomal membrane] (Danio rerio)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

GTP [cytosol]
rheb [lysosomal membrane] (Danio rerio)

Participates

as an input of

mTORC1 binds RHEB:GTP (Danio rerio)
Formation of active mTORC1 complex (Danio rerio)

as a component of

v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
Active mTORC1 complex [lysosomal membrane] (Danio rerio)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Danio rerio)

as an output of

GTP loading by Rheb (Danio rerio)

Inferred From

RHEB:GTP [lysosomal membrane] (Homo sapiens)