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inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate
Stable Identifier
R-GGA-421201
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Gallus gallus)
Nucleotide metabolism (Gallus gallus)
Purine metabolism (Gallus gallus)
De novo synthesis of AMP (Gallus gallus)
inosine 5'-monophosphate (IMP) + L-aspartate + GTP => adenylosuccinate + GDP + orthophosphate (Gallus gallus)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Cytosolic ADSS catalyzes the reaction of inosine 5'-monophosphate (IMP), aspartate, and GTP to form adenylosuccinate, GDP, and orthophosphate. While a chicken cDNA capable of encoding an ADSS-like protein has been identified, this protein has not been characterized experimentally and this reaction is inferred from its better-studied mouse counterpart.
Participants
Input
GTP [cytosol]
IMP [cytosol]
L-Asp [cytosol]
Output
ADS [cytosol]
GDP [cytosol]
Pi [cytosol]
Participates
as an event of
De novo synthesis of AMP (Gallus gallus)
Catalyst Activity
adenylosuccinate synthase activity of ADSS [cytosol]
Physical Entity
ADSS [cytosol]
(Gallus gallus)
Activity
adenylosuccinate synthase activity (GO:0004019)
Inferred From
inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate (Mus musculus)
Authored
D'Eustachio, P (2009-05-15)
Created
D'Eustachio, P (2009-05-16)
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