WNT:FZD complex promotes G-protein nucleotide exchange

Stable Identifier
R-HSA-3965444
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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After binding the FZD receptor, the G-protein alpha subunit exchanges GDP for GTP (reviewed in Malbon, 2004).

Literature References
PubMed ID Title Journal Year
14977528 Frizzleds: new members of the superfamily of G-protein-coupled receptors

Malbon, CC

Front. Biosci. 2004
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
guanyl-nucleotide exchange factor activity of WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created