Reactome | Guanine nucleotide exchange on RAL

Guanine nucleotide exchange on RAL

Stable Identifier

R-HSA-171026

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane, cytosol

Locations in the PathwayBrowser

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Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by NTRKs (Homo sapiens)
    - Signaling by NTRK1 (TRKA) (Homo sapiens)
      - Signalling to ERKs (Homo sapiens)
        
        Signalling to RAS (Homo sapiens)
        
        p38MAPK events (Homo sapiens)
        
        Guanine nucleotide exchange on RAL (Homo sapiens)

General

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The Ras-related protein, RAL becomes activated once GDP is replaced by GTP.

Participants

Input

Output

Participant Of

hasEvent

p38MAPK events

Catalyst Activity

Title

Ral guanyl-nucleotide exchange factor activity of Ras-GTP:RalGDS complex [plasma membrane]

Physical Entity

Ras-GTP:RalGDS complex [plasma membrane]

Activity

Ral guanyl-nucleotide exchange factor activity (0008321)

Inferred From

Guanine nucleotide exchange on Ral (Rattus norvegicus)

Authored

Nasi, S (2006-10-10)

Annibali, D (2006-10-10)

Reviewed

Greene, LA (2007-11-08)

Created

Jassal, B (2006-01-25)

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