Reactome | Guanine nucleotide exchange on RAL

Guanine nucleotide exchange on RAL

Stable Identifier

R-HSA-171026

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane, cytosol

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by NTRKs (Homo sapiens)
    - Signaling by NTRK1 (TRKA) (Homo sapiens)
      - Signalling to ERKs (Homo sapiens)
        
        Signalling to RAS (Homo sapiens)
        
        p38MAPK events (Homo sapiens)
        
        Guanine nucleotide exchange on RAL (Homo sapiens)

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The Ras-related protein, RAL becomes activated once GDP is replaced by GTP.

Participants

Input

Output

Participant Of

hasEvent

p38MAPK events

Catalyst Activity

Title

Ral guanyl-nucleotide exchange factor activity of Ras-GTP:RalGDS complex [plasma membrane]

Physical Entity

Ras-GTP:RalGDS complex [plasma membrane]

Activity

Ral guanyl-nucleotide exchange factor activity (0008321)

Inferred From

Guanine nucleotide exchange on Ral (Rattus norvegicus)

Authored

Nasi, S (2006-10-10)

Annibali, D (2006-10-10)

Reviewed

Greene, LA (2007-11-08)

Created

Jassal, B (2006-01-25)