Gq activation by PAR

Stable Identifier
R-HSA-114558
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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Activated PAR stimulates the G alpha (q) subunit to release GDP and bind GTP (which is present in much greater concentrations physiologically). This activation is required for Gq to participate in downstream signalling events.

Literature References
PubMed ID Title Journal Year
16102047 Protease-activated receptors in hemostasis, thrombosis and vascular biology

Coughlin, SR

J Thromb Haemost 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
G protein-coupled receptor activity of Thrombin-activated PAR [plasma membrane]
Physical Entity
Activity
Orthologous Events
Created