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p21 RAS:GTP [plasma membrane]
Stable Identifier
R-DRE-109783
Type
Complex
Species
Danio rerio
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Hemostasis (Danio rerio)
Cell surface interactions at the vascular wall (Danio rerio)
Tie2 Signaling (Danio rerio)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Downstream signaling events of B Cell Receptor (BCR) (Danio rerio)
Activation of RAS in B cells (Danio rerio)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signal Transduction (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
Intrinsic nucleotide exchange on RAS (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Negative regulation of MAPK pathway (Danio rerio)
BRAP autoubiquitinates (Danio rerio)
p21 RAS:GTP:BRAP [plasma membrane] (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
BRAP binds RAS:GTP (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
p21 RAS:GTP:BRAP [plasma membrane] (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
RAS:GTP binds PI3K (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
p21 RAS:GTP:PI3K [plasma membrane] (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (q) signalling events (Danio rerio)
Gastrin-CREB signalling pathway via PKC and MAPK (Danio rerio)
EGFR Transactivation by Gastrin (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by Non-Receptor Tyrosine Kinases (Danio rerio)
Signaling by PTK6 (Danio rerio)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Danio rerio)
RASA1 binds RAS:GTP (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
p21 RAS:GTP:RASA1 [plasma membrane] (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
RASA1 stimulates RAS GTPase activity (Danio rerio)
p21 RAS:GTP:RASA1 [plasma membrane] (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by EGFR (Danio rerio)
GRB2 events in EGFR signaling (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
SHC1 events in EGFR signaling (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by ERBB2 (Danio rerio)
GRB2 events in ERBB2 signaling (Danio rerio)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by ERBB4 (Danio rerio)
SHC1 events in ERBB4 signaling (Danio rerio)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by FGFR (Danio rerio)
Signaling by FGFR1 (Danio rerio)
Downstream signaling of activated FGFR1 (Danio rerio)
FRS-mediated FGFR1 signaling (Danio rerio)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
SHC-mediated cascade:FGFR1 (Danio rerio)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by FGFR2 (Danio rerio)
Downstream signaling of activated FGFR2 (Danio rerio)
FRS-mediated FGFR2 signaling (Danio rerio)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
SHC-mediated cascade:FGFR2 (Danio rerio)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by FGFR3 (Danio rerio)
Downstream signaling of activated FGFR3 (Danio rerio)
FRS-mediated FGFR3 signaling (Danio rerio)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
SHC-mediated cascade:FGFR3 (Danio rerio)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by FGFR4 (Danio rerio)
Downstream signaling of activated FGFR4 (Danio rerio)
FRS-mediated FGFR4 signaling (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by MET (Danio rerio)
MET activates RAS signaling (Danio rerio)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by PDGF (Danio rerio)
Downstream signal transduction (Danio rerio)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
Signaling by SCF-KIT (Danio rerio)
Activation of RAS by p-KIT bound SOS1 (Danio rerio)
p21 RAS:GTP [plasma membrane] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GTP [cytosol]
mature p21 RAS [plasma membrane]
(Danio rerio)
Participates
as an output of
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Danio rerio)
Activation of RAS by p-KIT bound SOS1 (Danio rerio)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Danio rerio)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Danio rerio)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Danio rerio)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Danio rerio)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Danio rerio)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Danio rerio)
Intrinsic nucleotide exchange on RAS (Danio rerio)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Danio rerio)
RAS GEFs promote RAS nucleotide exchange (Danio rerio)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Danio rerio)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Danio rerio)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)
as a component of
RASA1:p21 RAS:GTP:SPG [plasma membrane] (Danio rerio)
p21 RAS:GTP:RASA1 [plasma membrane] (Danio rerio)
p21 RAS:GTP:PI3K [plasma membrane] (Danio rerio)
p21 RAS:GTP:ub-BRAP [plasma membrane] (Danio rerio)
p21 RAS:GTP:BRAP [plasma membrane] (Danio rerio)
as an input of
RASA1 binds RAS:GTP (Danio rerio)
RAS:GTP binds PI3K (Danio rerio)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Danio rerio)
BRAP binds RAS:GTP (Danio rerio)
Inferred From
p21 RAS:GTP [plasma membrane]
(Homo sapiens)
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