Two isoforms of adenylosuccinate synthetase, ADSS and ADSSL1, catalyze the reaction of IMP, aspartate, and GTP to form adenylosuccinate, GDP, and orthophosphate (Powell et al. 1992; Sun et al. 2005). ADSS is a homotetramer (unpublished crystallographic data - PDB 2V40) and ADSSL1 is inferred to be a tetramer likewise.
Powell, SM, Zalkin, H, Dixon, JE
Sun, H, Li, N, Wang, X, Chen, T, Shi, L, Zhang, L, Wang, J, Wan, T, Cao, X
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