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What is Reactome ?
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Team
Scientific Advisory Board
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Digital Preservation
Contact us
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Table of Contents
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GDP [cytosol]
Stable Identifier
R-ALL-29420
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Guanosine 5'-diphosphate, Guanosine diphosphate, GDP(3-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Active MTORC1 binds the ULK1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Active MTORC1 phosphorylates ULK1 (Bos taurus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1 dissociates from ULK complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Rheb in the MTORC1 complex hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Selective autophagy (Bos taurus)
Aggrephagy (Bos taurus)
Aggresome dissociates from dynein and microtubule (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)
Poly-vimentin:PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PolyUb-Misfolded Proteins:HDAC6:Microtubule:Dynein complex [microtubule organizing center] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Postmitotic nuclear pore complex (NPC) reformation (Bos taurus)
RAN stimulates fusion of nuclear envelope (NE) membranes (Bos taurus)
RAN:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RCC1 stimulates GDP to GTP exchange on RAN (Bos taurus)
GDP [cytosol]
RAN:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Separation of Sister Chromatids (Bos taurus)
ESPL1 (Separase) cleaves centromeric cohesin (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Separation of sister chromatids (Bos taurus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Sister Centromere:Kinetochore:Microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Mitotic Prometaphase (Bos taurus)
EML4 and NUDC in mitotic spindle formation (Bos taurus)
EML4 binds to microtubules (Bos taurus)
EML4 homotrimer:Microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
EML4 recruits NUDC to mitotic spindle (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinetochore capture of astral microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Recruitment of NuMA to mitotic centrosomes (Bos taurus)
Association of NuMA with microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Mature centrosome:nucleated microtubules [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinetochore assembly (Bos taurus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Bos taurus)
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GTSE1 binds microtubule lattice in interphase cells (Bos taurus)
GTSE1:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
GTSE1:MAPRE1:microtubule plus end [cytosol] (Bos taurus)
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MAPRE1:microtubule plus end [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to starvation (Bos taurus)
Amino acids regulate mTORC1 (Bos taurus)
RRAGA,B exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGA,B hydrolyzes GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,D exchanges GTP for GDP (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,D hydrolyzes GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Bos taurus)
RagA,B:GDP:RagC,D:GTP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 binds RHEB:GTP (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Bos taurus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Bos taurus)
RRAGA,B:GDP:RRAGC,D:GDP [cytosol] (Bos taurus)
RRAGA,B:GDP [cytosol] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGB:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH-ephrin mediated repulsion of cells (Bos taurus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
EPHA-mediated growth cone collapse (Bos taurus)
NGEF exchanges GTP for GDP on RHOA (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Bos taurus)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Bos taurus)
HRAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
L1CAM interactions (Bos taurus)
Recycling pathway of L1 (Bos taurus)
Formation of clathrin coated vesicle (Bos taurus)
GDP [cytosol]
Signal transduction by L1 (Bos taurus)
Activation of Rac1 by VAV2 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
NCAM signaling for neurite out-growth (Bos taurus)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Netrin-1 signaling (Bos taurus)
DCC mediated attractive signaling (Bos taurus)
Activation of Cdc42 (Bos taurus)
GDP [cytosol]
CDC42:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Activation of Rac1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Semaphorin interactions (Bos taurus)
Sema4D in semaphorin signaling (Bos taurus)
Sema4D induced cell migration and growth-cone collapse (Bos taurus)
Activation of Rho by LARG and PDZ-RhoGEF (Bos taurus)
GDP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Bos taurus)
Inactivation of Rho-GTP by p190RhoGAP (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by ROBO receptors (Bos taurus)
SLIT2:ROBO1 increases RHOA activity (Bos taurus)
MYO9B inactivates RHOA (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Drug ADME (Bos taurus)
Azathioprine ADME (Bos taurus)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
Tie2 Signaling (Bos taurus)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Factors involved in megakaryocyte development and platelet production (Bos taurus)
Kinesins (Bos taurus)
Kinesins bind microtubules (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinesins move along microtubules consuming ATP (Bos taurus)
Kinesins:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
VAV1 is a GEF for Rho/Rac family GTPases (Bos taurus)
GDP [cytosol]
VAV1 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
GDP [cytosol]
VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)
GDP [cytosol]
VAV2 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
GDP [cytosol]
VAV3 is a GEF for Rho/Rac family kinases (Bos taurus)
GDP [cytosol]
VAV3 Rho/Rac effectors:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 12 (Bos taurus)
Gi activation by P2Y purinoceptor 12 (Bos taurus)
GDP [cytosol]
Thromboxane signalling through TP receptor (Bos taurus)
G13 activation by TP receptor (Bos taurus)
GDP [cytosol]
Gq activation by TP receptor (Bos taurus)
GDP [cytosol]
Thrombin signalling through proteinase activated receptors (PARs) (Bos taurus)
Thrombin-activated PARs activate G12/13 (Bos taurus)
GDP [cytosol]
Thrombin-activated PARs activate Gq (Bos taurus)
GDP [cytosol]
Platelet homeostasis (Bos taurus)
Prostacyclin signalling through prostacyclin receptor (Bos taurus)
Gs activation by prostacyclin receptor (Bos taurus)
Prostacyclin:prostacyclin receptor:Gs (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Disassembly of COPII coated vesicle (Bos taurus)
GDP [cytosol]
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Costimulation by the CD28 family (Bos taurus)
CD28 co-stimulation (Bos taurus)
CD28 dependent Vav1 pathway (Bos taurus)
Activation of Cdc42 by pVav1 (Bos taurus)
GDP [cytosol]
CDC42:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Activation of Rac1 by pVav1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MHC class II antigen presentation (Bos taurus)
Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Bos taurus)
Arf1-GDP [cytosol] (Bos taurus)
GDP [cytosol]
Internalization of MHC II:Ii clathrin coated vesicle (Bos taurus)
GDP [cytosol]
Translocation of TGN-lysosome vesicle to lysosome (Bos taurus)
GDP [cytosol]
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Kinesins:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Rap1 signalling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Rap1 signal termination by Rap1GAPs (Bos taurus)
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of RAS in B cells (Bos taurus)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Innate Immune System (Bos taurus)
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
Activation of RAC1 by VAV2/3 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
Activation of RAC1 by VAV (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SOS mediated nucleotide exchange of RAS (SHC) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
Activation of RAC1 by CRKII:DOCK180:ELMO (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of RAC1 by VAV (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Mitochondrial Uncoupling (Bos taurus)
UCP1 imports a proton (Bos taurus)
Purine nucleotide [cytosol]
GDP [cytosol]
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Adrenaline,noradrenaline inhibits insulin secretion (Bos taurus)
Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)
GDP [cytosol]
G-alpha(i,o):GDP:G beta:G gamma [plasma membrane] (Bos taurus)
G-alpha(i,o):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Free fatty acids regulate insulin secretion (Bos taurus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)
FFAR1:FFAR1 ligands activate Gq (Bos taurus)
GDP [cytosol]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Bos taurus)
GLP1R binds GLP1 (Bos taurus)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R binds GLP1R agonists (Bos taurus)
GLP1R:GLP1R agonists [plasma membrane] (Bos taurus)
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAP1A exchanges GDP for GTP (Bos taurus)
GDP [cytosol]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PCK1 phosphorylates OA to yield PEP (Bos taurus)
GDP [cytosol]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Bos taurus)
(d)GDP [cytosol]
GDP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Bos taurus)
(d)GDP [cytosol]
GDP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)
(d)NDP [cytosol]
GDP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Bos taurus)
(d)NDP [cytosol]
GDP [cytosol]
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Bos taurus)
GDP [cytosol]
Metabolism of RNA (Bos taurus)
Nonsense-Mediated Decay (NMD) (Bos taurus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Bos taurus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Bos taurus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SMG6 hydrolyzes mRNA with premature termination codon (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Bos taurus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Bos taurus)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Bos taurus)
eRF3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Addition of a second mannose to the N-glycan precursor by ALG2 (Bos taurus)
GDP [cytosol]
Addition of the first mannose to the N-glycan precursor by ALG1 (Bos taurus)
GDP [cytosol]
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
Synthesis of dolichyl-phosphate mannose (Bos taurus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Bos taurus)
GDP [cytosol]
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
ARFGAPs stimulate ARF GTPase activity (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
ERGIC-to-Golgi vesicles bind dynein:dynactin (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 recruits ARF:GDP to the ERGIC (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
RAB1:GTP:GBF1:USO1:ARF:GDP [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
ARF:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Bos taurus)
Dynein:Dynactin:microtubule [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
COPII coat binds TRAPPCII and RAB1:GDP (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Loss of SAR1B GTPase (Bos taurus)
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Nucleotide exchange on RAB1 (Bos taurus)
GDP [cytosol]
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SAR1 Activation And Membrane Binding (Bos taurus)
GDP [cytosol]
SAR1B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Bos taurus)
RAB1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglycylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglycylated microtubule protofilament [cytosol] (Bos taurus)
Polyglycyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglycyl beta tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
TTLLs polyglutamylate tubulin (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglutamylated microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Polyglutamyl microtubule protofilament [cytosol] (Bos taurus)
Polyglutamyl alpha-beta tubulin dimer [cytosol] (Bos taurus)
Polyglutamyl beta tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Post-translational modification: synthesis of GPI-anchored proteins (Bos taurus)
Synthesis of dolichyl-phosphate mannose (Bos taurus)
dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Bos taurus)
GDP [cytosol]
Protein ubiquitination (Bos taurus)
E3 ubiquitin ligases ubiquitinate target proteins (Bos taurus)
RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Bos taurus)
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RNF152 polyubiquitinates RRAGA (Bos taurus)
K63polyUb-K142,K220,K230,K244-RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RNF152:RRAGA:GDP:Ub:UBE2N [lysosomal membrane] (Bos taurus)
RRAGA:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB geranylgeranylation (Bos taurus)
RGGT geranylgeranylates RAB proteins (Bos taurus)
CHMs:GGC-RABs:GDP [cytosol] (Bos taurus)
GGC-RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Bos taurus)
RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RGGT:CHM binds RABs (Bos taurus)
RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RGGT:CHMs:RABs:GDP [cytosol] (Bos taurus)
RABs:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Translation (Bos taurus)
Eukaryotic Translation Elongation (Bos taurus)
Regeneration of eEF1A:GTP by eEF1B activity (Bos taurus)
eEF1A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
eEF1B:GDP exchange complex [cytosol] (Bos taurus)
GDP [cytosol]
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
GTP hydrolysis and joining of the 60S ribosomal subunit (Bos taurus)
eIF5B:GTP is hydrolyzed and released (Bos taurus)
eIF5B:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Recycling of eIF2:GDP (Bos taurus)
Formation of eIF2:GDP:eIF2B intermediate (Bos taurus)
eIF2:GDP [cytosol] (Bos taurus)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Bos taurus)
GDP [cytosol]
eIF2 activation (Bos taurus)
GDP [cytosol]
eIF2:GDP: eIF2B [cytosol] (Bos taurus)
GDP [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
GABA receptor activation (Bos taurus)
GABA B receptor activation (Bos taurus)
Activation of GABAB receptors (Bos taurus)
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Organelle biogenesis and maintenance (Bos taurus)
Cilium Assembly (Bos taurus)
ATAT acetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
acetylated microtubule [cytosol] (Bos taurus)
acetylated microtubule protofilament [cytosol] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Anchoring of the basal body to the plasma membrane (Bos taurus)
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GDP [cytosol]
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Cargo trafficking to the periciliary membrane (Bos taurus)
VxPx cargo-targeting to cilium (Bos taurus)
ASAP1 stimulates GTPase activity of ARF4 (Bos taurus)
ARF4:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GBF1 stimulates nucleotide exchange on ARF4 (Bos taurus)
GDP [cytosol]
ARF4:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3IP and RAB8A bind to the ciliary targeting complex (Bos taurus)
RAB3IP:RAB8A:GDP [cytosol] (Bos taurus)
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAB3IP stimulates nucleotide exchange on RAB8A (Bos taurus)
GDP [cytosol]
RAB8A:GDP:RAB3IP:RAB11A:GTP:FIP3 dimer:ASAP1 dimer:VxPx-containing ciliary membrane proteins [Golgi membrane] (Bos taurus)
RAB8A:GDP [cytosol] (Bos taurus)
GDP [cytosol]
HDAC6 deacetylates microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
acetylated microtubule [cytosol] (Bos taurus)
acetylated microtubule protofilament [cytosol] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Intraflagellar transport (Bos taurus)
Anterograde IFT (Bos taurus)
anterograde IFT trains [ciliary tip] (Bos taurus)
active kinesin-2 motors [ciliary tip] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
anterograde IFT trains [cilium] (Bos taurus)
active kinesin-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Assembly of the anterograde IFT train (Bos taurus)
active kinesin-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
anterograde IFT trains [cilium] (Bos taurus)
active kinesin-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Retrograde IFT (Bos taurus)
retrograde IFT trains [ciliary tip] (Bos taurus)
active dynein-2 motors [ciliary tip] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
retrograde IFT trains [cilium] (Bos taurus)
active dynein-2 motors [cilium] (Bos taurus)
acetylated microtubule [axonemal microtubule] (Bos taurus)
Ac K40 alpha tubulin-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Sensory Perception (Bos taurus)
Olfactory Signaling Pathway (Bos taurus)
odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Bos taurus)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 [plasma membrane] (Bos taurus)
GNAL:GDP:GNB1:GNG13 [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
Bitter compound binds bitter taste receptor (TAS2R) (Bos taurus)
TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Bos taurus)
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Bos taurus)
TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
GNAT3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Visual phototransduction (Bos taurus)
The phototransduction cascade (Bos taurus)
Inactivation, recovery and regulation of the phototransduction cascade (Bos taurus)
GNAT1-GTP hydrolyses its bound GTP to GDP (Bos taurus)
GNAT1-GDP [photoreceptor disc membrane] (Bos taurus)
GDP [cytosol]
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
p75 NTR receptor-mediated signalling (Bos taurus)
Cell death signalling via NRAGE, NRIF and NADE (Bos taurus)
NRAGE signals death through JNK (Bos taurus)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Bos taurus)
GDP [cytosol]
p75NTR regulates axonogenesis (Bos taurus)
Axonal growth inhibition (RHOA activation) (Bos taurus)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The p75NTR:NgR:MDGI binds RHOA-GDI (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:RTN4R:LINGO1:RTN4,MAG,OMG [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Axonal growth stimulation (Bos taurus)
NGF binding to p75NTR inactivates RHOA (Bos taurus)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR:NGF [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p75NTR and RHOA-GDI interact (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA:GDP:ARHGDIA:NGFR [plasma membrane] (Bos taurus)
RHOA:GDP:ARHGDIA [plasma membrane] (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Integrin signaling (Bos taurus)
Activation of Rap1 by cytosolic GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of Rap1 by membrane-associated GEFs (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
MAF1 translocates to the nucleus (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 phosphorylates MAF1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
Intrinsic nucleotide exchange on RAS (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS GEFs promote RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS processing (Bos taurus)
mature p21 RAS binds GDP (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
MTOR signalling (Bos taurus)
AKT1S1 (PRAS40) binds mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Bos taurus)
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Formation of active mTORC1 complex (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
GTP loading by Rheb (Bos taurus)
GDP [cytosol]
RHEB:GDP [lysosomal membrane] (Bos taurus)
GDP [cytosol]
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Rag dimer formation (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator binds Rag dimers (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SLC38A9 binds Ragulator:Rag dimers (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 phosphorylates AKT1S1 (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1-mediated signalling (Bos taurus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1 with p-S722,S792-RPTOR:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Bos taurus)
mTORC1 with p-RPTOR:Ragulator:Rag:GNP [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Bos taurus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Bos taurus)
Active mTORC1 complex [lysosomal membrane] (Bos taurus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Bos taurus)
Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] (Bos taurus)
RagA,B:GTP:RagC,D:GDP [cytosol] (Bos taurus)
RRAGC,RRAGD:GDP [cytosol] (Bos taurus)
RRAGC:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RRAGD:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (12/13) signalling events (Bos taurus)
GEFs activate RhoA,B,C (Bos taurus)
GDP [cytosol]
Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Bos taurus)
GDP [cytosol]
p115-RhoGEF activation of RHOA (Bos taurus)
GDP [cytosol]
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (i) signalling events (Bos taurus)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Bos taurus)
G alpha (i):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Bos taurus)
G alpha (i):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
GDP [cytosol]
Opioid Signalling (Bos taurus)
G-protein activation (Bos taurus)
G-protein alpha subunit is inactivated (Bos taurus)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G-protein beta-gamma subunits rebind the alpha-GDP subunit (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The high affinity receptor complex binds to G-protein (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
The receptor:G-protein complex releases GDP (Bos taurus)
GDP [cytosol]
Opioid:MOR:G protein-GDP complex [plasma membrane] (Bos taurus)
G protein-GDP complex [plasma membrane] (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G-protein mediated events (Bos taurus)
Adenylate cyclase activating pathway (Bos taurus)
Adenylaye cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha-olf:GDP:Adenylate cyclase (active) complex [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Adenylate cyclase inhibitory pathway (Bos taurus)
Adenylate cyclase increases the GTPase activity of G alpha-olf (Bos taurus)
(Gi alpha1:GTP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
Dissociation of the Gi alpha:G olf complex (Bos taurus)
(Gi alpha1:GDP:Adenylate cyclase):(G alpha-olf:GDP) [plasma membrane] (Bos taurus)
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha-olf:GDP complex [plasma membrane] (Bos taurus)
GDP [cytosol]
PLC beta mediated events (Bos taurus)
Inactivation of PLC beta (Bos taurus)
G-protein alpha:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Opsins act as GEFs for G alpha-t (Bos taurus)
GDP [cytosol]
G alpha (q) signalling events (Bos taurus)
G alpha (q) in G (q):RGS complex is inactivated (Bos taurus)
G alpha (q):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (q):RGS dissociates to inactive G alpha (q) (Bos taurus)
G alpha (q):GDP:RGS [plasma membrane] (Bos taurus)
GDP [cytosol]
Gastrin-CREB signalling pathway via PKC and MAPK (Bos taurus)
EGFR Transactivation by Gastrin (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
GDP [cytosol]
G alpha (s) signalling events (Bos taurus)
Liganded Gs-activating GPCR acts as a GEF for Gs (Bos taurus)
GDP [cytosol]
Ade-Rib:ADORA2B:Heterotrimeric G-protein Gs:GDP [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (z) signalling events (Bos taurus)
G alpha (z) in G alpha (z):RGS complex is inactivated (Bos taurus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Bos taurus)
GDP [cytosol]
G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Bos taurus)
G alpha (z):GDP:RGS16,17,20 [plasma membrane] (Bos taurus)
GDP [cytosol]
Liganded Gz-activating GPCR acts as a GEF for Gz (Bos taurus)
GDP [cytosol]
GPCR ligand binding (Bos taurus)
Class B/2 (Secretin family receptors) (Bos taurus)
Glucagon-type ligand receptors (Bos taurus)
GLP1R binds GLP1 (Bos taurus)
GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Bos taurus)
G alpha (s):GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Hedgehog (Bos taurus)
Hedgehog 'off' state (Bos taurus)
KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Bos taurus)
KIF7:microtubule [ciliary tip] (Bos taurus)
microtubule [axonemal microtubule] (Bos taurus)
alpha-beta tubulin dimer [axonemal microtubule] (Bos taurus)
beta tubulin:GDP [axonemal microtubule] (Bos taurus)
GDP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Bos taurus)
Signaling by PTK6 (Bos taurus)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Bos taurus)
ARHGAP35 stimulates RHOA GTPase activity (Bos taurus)
RHOA:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activation of RAC1 by the PXN:CRK complex (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RASA1 stimulates RAS GTPase activity (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
PRKCZ recruits RAS in response to estrogen stimulation (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by EGFR (Bos taurus)
GRB2 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC1 events in EGFR signaling (Bos taurus)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by ERBB2 (Bos taurus)
GRB2 events in ERBB2 signaling (Bos taurus)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by ERBB4 (Bos taurus)
SHC1 events in ERBB4 signaling (Bos taurus)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Downstream signaling of activated FGFR1 (Bos taurus)
FRS-mediated FGFR1 signaling (Bos taurus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR1 (Bos taurus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR2 (Bos taurus)
Downstream signaling of activated FGFR2 (Bos taurus)
FRS-mediated FGFR2 signaling (Bos taurus)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR2 (Bos taurus)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
FRS-mediated FGFR3 signaling (Bos taurus)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR3 (Bos taurus)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by MET (Bos taurus)
MET activates RAS signaling (Bos taurus)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
MET promotes cell motility (Bos taurus)
MET activates RAP1 and RAC1 (Bos taurus)
DOCK7 activates RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAPGEF1 activates RAP1 (Bos taurus)
GDP [cytosol]
RAP1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
ARMS-mediated activation (Bos taurus)
C3G stimulates nucleotide exchange on Rap1 (Bos taurus)
GDP [cytosol]
Rap1-GDP [cytosol] (Bos taurus)
GDP [cytosol]
Signaling by NTRK2 (TRKB) (Bos taurus)
Activated NTRK2 signals through FYN (Bos taurus)
NTRK2 activates RAC1 (Bos taurus)
DOCK3 activates RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by PDGF (Bos taurus)
Downstream signal transduction (Bos taurus)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by SCF-KIT (Bos taurus)
Activation of RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Activation of RAS by p-KIT bound SOS1 (Bos taurus)
GDP [cytosol]
p21 RAS:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p-VAV family:PIP3 binds RAC1:GDP (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Miro GTPase Cycle (Bos taurus)
RHOT1 GTPase cycle (Bos taurus)
RHOT1 hydrolyzes GTP (Bos taurus)
RHOT1:GDP [mitochondrial outer membrane] (Bos taurus)
GDP [cytosol]
RHOT2 GTPase cycle (Bos taurus)
RHOT2 hydrolyzes GTP (Bos taurus)
RHOT2:GDP [mitochondrial outer membrane] (Bos taurus)
GDP [cytosol]
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
Microtubule-bound kinetochore [cytosol] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Bos taurus)
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHO GTPases activate IQGAPs (Bos taurus)
IQGAP1 binds CLIP1 and microtubules (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC1,CDC42:GTP:IQGAP1:CLIP1:microtubule [plasma membrane] (Bos taurus)
Microtubule [cytosol] (Bos taurus)
Microtubule protofilament [cytosol] (Bos taurus)
alpha-beta tubulin dimer [cytosol] (Bos taurus)
beta-tubulin:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RHO GTPase cycle (Bos taurus)
CDC42 GTPase cycle (Bos taurus)
CDC42 GAPs stimulate CDC42 GTPase activity (Bos taurus)
CDC42:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
CDC42 GDIs block activation of CDC42 (Bos taurus)
CDC42:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
CDC42:GDP:CDC42 GDIs [cytosol] (Bos taurus)
CDC42:GDP [cytosol] (Bos taurus)
GDP [cytosol]
CDC42 GEFs activate CDC42 (Bos taurus)
GDP [cytosol]
CDC42:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC1 GTPase cycle (Bos taurus)
RAC1 GAPs stimulate RAC1 GTPase activity (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC1 GDIs block activation of RAC1 (Bos taurus)
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC1:GDP:RAC1 GDIs [cytosol] (Bos taurus)
RAC1:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC1 GEFs activate RAC1 (Bos taurus)
GDP [cytosol]
RAC1:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC2 GTPase cycle (Bos taurus)
RAC2 GAPs stimulate RAC2 GTPase activity (Bos taurus)
RAC2:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC2 GDIs block activation of RAC2 (Bos taurus)
ARHGDIA:RAC2:GDP [cytosol] (Bos taurus)
RAC2:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC2 GEFs activate RAC2 (Bos taurus)
GDP [cytosol]
RAC2:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC3 GTPase cycle (Bos taurus)
RAC3 GAPs stimulate RAC3 GTPase activity (Bos taurus)
RAC3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC3 GDIs block activation of RAC3 (Bos taurus)
RAC3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RAC3:GDP:RAC3 GDIs [cytosol] (Bos taurus)
RAC3:GDP [cytosol] (Bos taurus)
GDP [cytosol]
RAC3 GEFs activate RAC3 (Bos taurus)
GDP [cytosol]
RAC3:GDP [plasma membrane] (Bos taurus)
GDP [cytosol]
RHOA GTPase cycle (Bos taurus)