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p21 RAS:GDP [plasma membrane]
Stable Identifier
R-CEL-109796
Type
Complex
Species
Caenorhabditis elegans
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
NCAM signaling for neurite out-growth (Caenorhabditis elegans)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Hemostasis (Caenorhabditis elegans)
Cell surface interactions at the vascular wall (Caenorhabditis elegans)
Tie2 Signaling (Caenorhabditis elegans)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Signaling by the B Cell Receptor (BCR) (Caenorhabditis elegans)
Downstream signaling events of B Cell Receptor (BCR) (Caenorhabditis elegans)
Activation of RAS in B cells (Caenorhabditis elegans)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Cytokine Signaling in Immune system (Caenorhabditis elegans)
FLT3 Signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
Intrinsic nucleotide exchange on RAS (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
RAS processing (Caenorhabditis elegans)
mature p21 RAS binds GDP (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (q) signalling events (Caenorhabditis elegans)
Gastrin-CREB signalling pathway via PKC and MAPK (Caenorhabditis elegans)
EGFR Transactivation by Gastrin (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
Estrogen-stimulated signaling through PRKCZ (Caenorhabditis elegans)
PRKCZ recruits RAS in response to estrogen stimulation (Caenorhabditis elegans)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Caenorhabditis elegans)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by EGFR (Caenorhabditis elegans)
GRB2 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
SHC1 events in EGFR signaling (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by ERBB2 (Caenorhabditis elegans)
GRB2 events in ERBB2 signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by FGFR (Caenorhabditis elegans)
Signaling by FGFR1 (Caenorhabditis elegans)
Downstream signaling of activated FGFR1 (Caenorhabditis elegans)
FRS-mediated FGFR1 signaling (Caenorhabditis elegans)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by FGFR2 (Caenorhabditis elegans)
Downstream signaling of activated FGFR2 (Caenorhabditis elegans)
FRS-mediated FGFR2 signaling (Caenorhabditis elegans)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
SHC-mediated cascade:FGFR2 (Caenorhabditis elegans)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by FGFR3 (Caenorhabditis elegans)
Downstream signaling of activated FGFR3 (Caenorhabditis elegans)
FRS-mediated FGFR3 signaling (Caenorhabditis elegans)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
SHC-mediated cascade:FGFR3 (Caenorhabditis elegans)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by FGFR4 (Caenorhabditis elegans)
Downstream signaling of activated FGFR4 (Caenorhabditis elegans)
FRS-mediated FGFR4 signaling (Caenorhabditis elegans)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by MET (Caenorhabditis elegans)
MET activates RAS signaling (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by PDGF (Caenorhabditis elegans)
Downstream signal transduction (Caenorhabditis elegans)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
Signaling by SCF-KIT (Caenorhabditis elegans)
Activation of RAS by p-KIT bound SOS1 (Caenorhabditis elegans)
p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GDP [cytosol]
mature p21 RAS [plasma membrane]
(Caenorhabditis elegans)
Participates
as an input of
Activation of RAS by p-KIT bound SOS1 (Caenorhabditis elegans)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Caenorhabditis elegans)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)
PRKCZ recruits RAS in response to estrogen stimulation (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Caenorhabditis elegans)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Caenorhabditis elegans)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Caenorhabditis elegans)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Caenorhabditis elegans)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Caenorhabditis elegans)
Intrinsic nucleotide exchange on RAS (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Caenorhabditis elegans)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Caenorhabditis elegans)
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Caenorhabditis elegans)
as a component of
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Caenorhabditis elegans)
as an output of
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Caenorhabditis elegans)
mature p21 RAS binds GDP (Caenorhabditis elegans)
Inferred From
p21 RAS:GDP [plasma membrane]
(Homo sapiens)
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