Reactome | beta-tubulin:GDP [cytosol]

beta-tubulin:GDP [cytosol]

Stable Identifier

R-CEL-190512

Type

Complex

Species

Caenorhabditis elegans

Compartment

cytosol

Locations in the PathwayBrowser

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Cellular responses to stimuli (Caenorhabditis elegans)

- Cellular responses to stress (Caenorhabditis elegans)
  - HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Caenorhabditis elegans)
    - HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Caenorhabditis elegans)
      - Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)

Hemostasis (Caenorhabditis elegans)

- Factors involved in megakaryocyte development and platelet production (Caenorhabditis elegans)
  - Kinesins (Caenorhabditis elegans)
    - Kinesins move along microtubules consuming ATP (Caenorhabditis elegans)
      - Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Asparagine N-linked glycosylation (Caenorhabditis elegans)
    - Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
      - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
        
        COPI-mediated anterograde transport (Caenorhabditis elegans)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - ER to Golgi Anterograde Transport (Caenorhabditis elegans)
    - COPI-mediated anterograde transport (Caenorhabditis elegans)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
    - Golgi-to-ER retrograde transport (Caenorhabditis elegans)
      - COPI-dependent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Caenorhabditis elegans)
        
        Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
      - COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubules:PAFAH1B1 [cytosol] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)
        
        RAB6:GTP:BICD dimer:COPI-independent retrograde cargo:Dynein:Dynactin:microtubules [Golgi membrane] (Caenorhabditis elegans)
        
        Dynein:Dynactin:microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule [cytosol] (Caenorhabditis elegans)
        
        Microtubule protofilament [cytosol] (Caenorhabditis elegans)
        
        alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)
        
        beta-tubulin:GDP [cytosol] (Caenorhabditis elegans)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as a component of

alpha-beta tubulin dimer [cytosol] (Caenorhabditis elegans)

Inferred From

beta-tubulin:GDP [cytosol] (Homo sapiens)

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