ALG11 transfers the fourth and fifth Man to the N-glycan precursor

Stable Identifier
R-HSA-446187
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Addition of a fourth and fifth mannose to the N-glycan precursor by ALG11
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A fourth mannose is added to the N-glycan precursor by ALG11. The addition of the fifth mannose, also by ALG11, is the last step occurring on the cytosolic side of the ER membrane (Cipollo JF et al, 2001). Both these reactions are alpha1,2 mannose additions.

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
alpha-1,2-mannosyltransferase activity of ALG11 [endoplasmic reticulum membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created