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p21 RAS:GDP [plasma membrane]
Stable Identifier
R-SSC-109796
Type
Complex
Species
Sus scrofa
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Developmental Biology (Sus scrofa)
Nervous system development (Sus scrofa)
Axon guidance (Sus scrofa)
NCAM signaling for neurite out-growth (Sus scrofa)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Hemostasis (Sus scrofa)
Cell surface interactions at the vascular wall (Sus scrofa)
Tie2 Signaling (Sus scrofa)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Signaling by the B Cell Receptor (BCR) (Sus scrofa)
Downstream signaling events of B Cell Receptor (BCR) (Sus scrofa)
Activation of RAS in B cells (Sus scrofa)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
FLT3 Signaling (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Innate Immune System (Sus scrofa)
DAP12 interactions (Sus scrofa)
DAP12 signaling (Sus scrofa)
SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Fc epsilon receptor (FCERI) signaling (Sus scrofa)
FCERI mediated MAPK activation (Sus scrofa)
SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signal Transduction (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
Intrinsic nucleotide exchange on RAS (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
RAS processing (Sus scrofa)
mature p21 RAS binds GDP (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Regulation of RAS by GAPs (Sus scrofa)
RAS GAPs stimulate RAS GTPase activity (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (q) signalling events (Sus scrofa)
Gastrin-CREB signalling pathway via PKC and MAPK (Sus scrofa)
EGFR Transactivation by Gastrin (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Sus scrofa)
RASA1 stimulates RAS GTPase activity (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Extra-nuclear estrogen signaling (Sus scrofa)
Estrogen-stimulated signaling through PRKCZ (Sus scrofa)
PRKCZ recruits RAS in response to estrogen stimulation (Sus scrofa)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Sus scrofa)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by EGFR (Sus scrofa)
GRB2 events in EGFR signaling (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
SHC1 events in EGFR signaling (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by ERBB2 (Sus scrofa)
GRB2 events in ERBB2 signaling (Sus scrofa)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by ERBB4 (Sus scrofa)
SHC1 events in ERBB4 signaling (Sus scrofa)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by FGFR (Sus scrofa)
Signaling by FGFR1 (Sus scrofa)
Downstream signaling of activated FGFR1 (Sus scrofa)
FRS-mediated FGFR1 signaling (Sus scrofa)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
SHC-mediated cascade:FGFR1 (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by FGFR2 (Sus scrofa)
Downstream signaling of activated FGFR2 (Sus scrofa)
FRS-mediated FGFR2 signaling (Sus scrofa)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
SHC-mediated cascade:FGFR2 (Sus scrofa)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by FGFR3 (Sus scrofa)
Downstream signaling of activated FGFR3 (Sus scrofa)
FRS-mediated FGFR3 signaling (Sus scrofa)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
SHC-mediated cascade:FGFR3 (Sus scrofa)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by FGFR4 (Sus scrofa)
Downstream signaling of activated FGFR4 (Sus scrofa)
FRS-mediated FGFR4 signaling (Sus scrofa)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
SHC-mediated cascade:FGFR4 (Sus scrofa)
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by MET (Sus scrofa)
MET activates RAS signaling (Sus scrofa)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by PDGF (Sus scrofa)
Downstream signal transduction (Sus scrofa)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
Signaling by SCF-KIT (Sus scrofa)
Activation of RAS by p-KIT bound SOS1 (Sus scrofa)
p21 RAS:GDP [plasma membrane] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
GDP [cytosol]
mature p21 RAS [plasma membrane]
(Sus scrofa)
Participates
as an input of
Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Sus scrofa)
p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Sus scrofa)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)
PRKCZ recruits RAS in response to estrogen stimulation (Sus scrofa)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Sus scrofa)
Activation of RAS by p-KIT bound SOS1 (Sus scrofa)
Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)
Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Sus scrofa)
SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Sus scrofa)
RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Sus scrofa)
Intrinsic nucleotide exchange on RAS (Sus scrofa)
SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Sus scrofa)
RAS GEFs promote RAS nucleotide exchange (Sus scrofa)
RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Sus scrofa)
RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Sus scrofa)
RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Sus scrofa)
RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Sus scrofa)
as a component of
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Sus scrofa)
as an output of
RASA1 stimulates RAS GTPase activity (Sus scrofa)
RAS GAPs stimulate RAS GTPase activity (Sus scrofa)
RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Sus scrofa)
mature p21 RAS binds GDP (Sus scrofa)
Inferred From
p21 RAS:GDP [plasma membrane]
(Homo sapiens)
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