Reactome | RHOA:GDP [plasma membrane]

RHOA:GDP [plasma membrane]

Stable Identifier

R-MMU-8964174

Type

Complex

Species

Mus musculus

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

GDP [cytosol]
Rhoa [plasma membrane] (Mus musculus)

Participates

as an output of

RHOA GAPs stimulate RHOA GTPase activity (Mus musculus)
MYO9B inactivates RHOA (Mus musculus)
Inactivation of Rho-GTP by p190RhoGAP (Mus musculus)
The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Mus musculus)
ARHGAP35 stimulates RHOA GTPase activity (Mus musculus)

as an input of

GDIs block activation of RHOA (Mus musculus)
RHOA GEFs activate RHOA (Mus musculus)
p115-RhoGEF activation of RHOA (Mus musculus)
p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Mus musculus)
RhoA is activated by nucleotide exchange and inhibits axonal growth (Mus musculus)
NGEF exchanges GTP for GDP on RHOA (Mus musculus)

as a component of

RHOA:GDP:ARHGDIA [plasma membrane] (Mus musculus)

Inferred From

RHOA:GDP [plasma membrane] (Homo sapiens)