The receptor:G-protein complex releases GDP

Stable Identifier
R-HSA-167419
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
The receptor:G-protein complex releases GDP
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
G proteins are inactive in the GDP-bound state. The ternary complex neurotransmitter:receptor:G-protein releases GDP.
Literature References
PubMed ID Title Journal Year
16892066 Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins

Preininger, AM, Hubbell, WL, Van Eps, N, Oldham, WM, Hamm, HE

Nat Struct Mol Biol 2006
Participants
Input
Output
Participates
as an event of
Orthologous Events
The receptor:G-protein complex releases GDP (Bos taurus)
The receptor:G-protein complex releases GDP (Caenorhabditis elegans)
The receptor:G-protein complex releases GDP (Canis familiaris)
The receptor:G-protein complex releases GDP (Drosophila melanogaster)
The receptor:G-protein complex releases GDP (Gallus gallus)
The receptor:G-protein complex releases GDP (Mus musculus)
The receptor:G-protein complex releases GDP (Rattus norvegicus)
The receptor:G-protein complex releases GDP (Sus scrofa)
The receptor:G-protein complex releases GDP (Xenopus tropicalis)
Authored
Jassal, B  (2004-03-31)
Le Novere, N  (2004-03-31)
Reviewed
Castagnoli, L  (2008-11-06)
Created
Jassal, B  (2005-10-18)
Cite Us!