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GBP1 oligomer:GDP:LPS [cytosol]
Stable Identifier
R-HSA-9947863
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Enterobacteria (Homo sapiens)
Enterobacterial factors antagonize host defense (Homo sapiens)
CASP4 binds CALM:OspC3 (Homo sapiens)
CALM:OspC3:CASP4:LPS, CALM:OspC3:CASP4:LPS:GBPs [cytosol] (Homo sapiens)
CALM:OspC3:CASP4:LPS:GBPs [cytosol] (Homo sapiens)
2xCASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
CASP4:LPS, CASP4:LPS:GBPs [cytosol] (Homo sapiens)
2xCASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
OspC3 ADP-riboxanates CASP4 (Homo sapiens)
ADPrbx-R314-CASP4:LPS, ADPrbx-R314-CASP4:LPS:GBPs [cytosol] (Homo sapiens)
2xADPrbx-R314-CASP4:LPS:GBPs [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
CALM:OspC3:CASP4:LPS, CALM:OspC3:CASP4:LPS:GBPs [cytosol] (Homo sapiens)
CALM:OspC3:CASP4:LPS:GBPs [cytosol] (Homo sapiens)
2xCASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antimicrobial mechanism of IFN-stimulated genes (Homo sapiens)
GBP-mediated host defense (Homo sapiens)
GBP1 hydrolyzes GDP (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
GBP1 hydrolyzes GTP forming GBP1 oligomers (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
GBP1:GBP2:GBP3:GBP4 forms higher-order structures (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GTP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
GBP2, GBP3, GBP4 bind to GBP1 oligomer on the bacterial surface (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GTP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
Non-canonical inflammasome activation (Homo sapiens)
CASP4 inflammasome assembly (Homo sapiens)
CASP4 autocatalysis on the bacterial surface (Homo sapiens)
2xCASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
CALM:OspC3:CASP4:LPS:GBPs [cytosol] (Homo sapiens)
2xCASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
CASP4 binds exposed LPS on the bacterial surface (Homo sapiens)
CASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
CASP4 forms dimers on the bacterial surface (Homo sapiens)
2xCASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
CASP4:LPS:(GBP1:GBP2:GBP3:GBP4:GDP) oligomer [cytosol] (Homo sapiens)
LPS:(GBP1:GBP2:GBP3:GBP4) oligomer [cytosol] (Homo sapiens)
LPS:GBP1 oligomer:GBP2:GBP3:GBP4:GDP [cytosol] (Homo sapiens)
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
GBP1 oligomer:GDP:LPS [cytosol] (Homo sapiens)
Participants
components
GBP1 oligomer [cytosol]
(Homo sapiens)
x 2
GDP [cytosol]
LPS [peptidoglycan-based cell wall]
Participates
as an input of
GBP1 hydrolyzes GDP (Homo sapiens)
as an output of
GBP1 hydrolyzes GTP forming GBP1 oligomers (Homo sapiens)
as a member of
LPS-bound GBP1 oligomer [cytosol] (Homo sapiens)
Inferred To
GBP1 oligomer:GDP:LPS [cytosol]
(Bos taurus)
GBP1 oligomer:GDP:LPS [cytosol]
(Canis familiaris)
GBP1 oligomer:GDP:LPS [cytosol]
(Danio rerio)
GBP1 oligomer:GDP:LPS [cytosol]
(Dictyostelium discoideum)
GBP1 oligomer:GDP:LPS [cytosol]
(Gallus gallus)
GBP1 oligomer:GDP:LPS [cytosol]
(Rattus norvegicus)
GBP1 oligomer:GDP:LPS [cytosol]
(Sus scrofa)
GBP1 oligomer:GDP:LPS [cytosol]
(Xenopus tropicalis)
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