Reactome | TP53 R337C [nucleoplasm]

TP53 R337C [nucleoplasm]

Stable Identifier

R-HSA-9726118

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Diseases of programmed cell death (Homo sapiens)
  - Defective Intrinsic Pathway for Apoptosis (Homo sapiens)
    - Loss of Function of TP53 in Cancer (Homo sapiens)
      - Loss of function of TP53 in cancer due to loss of tetramerization ability (Homo sapiens)
        
        Defective TP53 does not tetramerize (Homo sapiens)
        
        TP53 mutants (tetramerization) [nucleoplasm] (Homo sapiens)
        
        TP53 R337C [nucleoplasm] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
9704930	Characterization of p53 oligomerization domain mutations isolated from Li-Fraumeni and Li-Fraumeni like family members Lomax, ME, Barnes, DM, Hupp, TR, Picksley, SM, Camplejohn, RS	Oncogene	1998
10653977	Function, oligomerization, and conformation of tumor-associated p53 proteins with mutated C-terminus Atz, J, Wagner, P, Roemer, K	J Cell Biochem	2000
9766574	Characterization of p53 mutants identified in human tumors with a missense mutation in the tetramerization domain Rollenhagen, C, Chène, P	Int J Cancer	1998
9704931	Characterization of the oligomerization defects of two p53 mutants found in families with Li-Fraumeni and Li-Fraumeni-like syndrome Davison, TS, Yin, P, Nie, E, Kay, C, Arrowsmith, CH	Oncogene	1998

External Reference Information

External Reference

UniProt:P04637 TP53

Gene Names

TP53, P53

Chain

chain:1-393

Reference Genes

BioGPS Gene:7157 TP53

COSMIC - genes:TP53 TP53

CTD Gene:7157 TP53

dbSNP Gene:7157 TP53

ENSEMBL:ENSG00000141510 TP53

HGNC:11998 TP53

KEGG:hsa:7157 TP53

Monarch:7157 TP53

NCBI Gene:7157 TP53

OMIM:191170 TP53

UCSC:P04637 TP53

Reference Transcript

Participates

as a member of

TP53 mutants (tetramerization) [nucleoplasm] (Homo sapiens)

Other forms of this molecule

Unfolded TP53 [cytosol]

TP53 [cytosol]

PolyUb-TP53 [nucleoplasm]

polySUMO2,3-K386-TP53 [nucleoplasm]

TP53 F341C [nucleoplasm]

TP53 G334V [nucleoplasm]

TP53 L330H [nucleoplasm]

TP53 A347T [nucleoplasm]

TP53 L344P [nucleoplasm]

TP53 L344R [nucleoplasm]

TP53 R337H [nucleoplasm]

TP53 R337P [nucleoplasm]

TP53 L330P [nucleoplasm]

TP53 L348S [nucleoplasm]

TP53 R337L [nucleoplasm]

TP53 K351E [nucleoplasm]

TP53 F338I [nucleoplasm]

TP53 R342P [nucleoplasm]

TP53 L330R [nucleoplasm]

TP53 R196Pfs*13 [nucleoplasm]

TP53 E224Rfs*23 [nucleoplasm]

TP53 F109Lfs*36 [nucleoplasm]

TP53 A78Sfs*71 [nucleoplasm]

TP53 T253Hfs*11 [nucleoplasm]

TP53 M169Dfs*11 [nucleoplasm]

TP53 T253Pfs*92 [nucleoplasm]

TP53 S260Pfs*85 [nucleoplasm]

TP53 Q317Sfs*28 [nucleoplasm]

TP53 R280Efs*26 [nucleoplasm]

TP53 H178Tfs*69 [nucleoplasm]

TP53 T312Pfs*33 [nucleoplasm]

TP53 Y234Pfs*7 [nucleoplasm]

TP53 Q52Pfs*5 [nucleoplasm]

TP53 S269Lfs*75 [nucleoplasm]

TP53 E271Gfs*73 [nucleoplasm]

TP53 K321Efs*16 [nucleoplasm]

TP53 D259Tfs*86 [nucleoplasm]

TP53 K292Gfs*52 [nucleoplasm]

TP53 I195Tfs*52 [nucleoplasm]

TP53 P75Lfs*74 [nucleoplasm]

TP53 I195Sfs*52 [nucleoplasm]

TP53 C229Lfs*18 [nucleoplasm]

TP53 K120Tfs*2 [nucleoplasm]

TP53 A119Qfs*5 [nucleoplasm]

TP53 Q192Pfs*17 [nucleoplasm]

TP53 L93Pfs*59 [nucleoplasm]

TP53 N29Tfs*15 [nucleoplasm]

TP53 I195Cfs*46 [nucleoplasm]

TP53 Y234Lfs*4 [nucleoplasm]

TP53 E204Sfs*43 [nucleoplasm]

TP53 V216Gfs*5 [nucleoplasm]

TP53 R248Pfs*95 [nucleoplasm]

TP53 V216Gfs*4 [nucleoplasm]

TP53 G293Efs*3 [nucleoplasm]

TP53 K139Nfs*9 [nucleoplasm]

TP53 Q16Rfs*28 [nucleoplasm]

TP53 A83Cfs*63 [nucleoplasm]

TP53 T230Hfs*9 [nucleoplasm]

TP53 I254Hfs*8 [nucleoplasm]

TP53 R213* [nucleoplasm]

TP53 I162Sfs*8 [nucleoplasm]

TP53 E294* [nucleoplasm]

TP53 D186Wfs*22 [nucleoplasm]

TP53 D228* [nucleoplasm]

TP53 S121Cfs*27 [nucleoplasm]

TP53 Q144Afs*5 [nucleoplasm]

TP53 D48* [nucleoplasm]

TP53 A161Hfs*19 [nucleoplasm]

TP53 Q144Rfs*26 [nucleoplasm]

TP53 E286Sfs*17 [nucleoplasm]

TP53 V122Afs*46 [nucleoplasm]

TP53 T123Hfs*24 [nucleoplasm]

TP53 D48Efs*75 [nucleoplasm]

TP53 E56* [nucleoplasm]

TP53 T211Ifs*4 [nucleoplasm]

TP53 P128Qfs*18 [nucleoplasm]

TP53 D184Ifs*63 [nucleoplasm]

TP53 C135Yfs*9 [nucleoplasm]

TP53 E298Tfs*48 [nucleoplasm]

TP53 G279* [nucleoplasm]

TP53 G154Afs*28 [nucleoplasm]

TP53 E68Gfs*80 [nucleoplasm]

TP53 T256Ifs*90 [nucleoplasm]

TP53 L43* [nucleoplasm]

TP53 M44Tfs*75 [nucleoplasm]

TP53 D207Mfs*40 [nucleoplasm]

TP53 Q317Pfs*20 [nucleoplasm]

TP53 N239Kfs*25 [nucleoplasm]

TP53 E258Pfs*85 [nucleoplasm]

TP53 P223* [nucleoplasm]

TP53 M243Hfs*18 [nucleoplasm]

TP53 L35Cfs*9 [nucleoplasm]

TP53 L35* [nucleoplasm]

TP53 T253Ifs*93 [nucleoplasm]

TP53 P322Hfs*23 [nucleoplasm]

TP53 A86Pfs*33 [nucleoplasm]

TP53 L114Ffs*35 [nucleoplasm]

TP53 G199* [nucleoplasm]

TP53 L111Qfs*13 [nucleoplasm]

TP53 G59Efs*58 [nucleoplasm]

TP53 T155Pfs*25 [nucleoplasm]

TP53 N268Pfs*45 [nucleoplasm]

TP53 H178Afs*65 [nucleoplasm]

TP53 E271Gfs*74 [nucleoplasm]

TP53 L35Ffs*7 [nucleoplasm]

TP53 G266Efs*4 [nucleoplasm]

TP53 E287* [nucleoplasm]

TP53 S94* [nucleoplasm]

TP53 S315Pfs*31 [nucleoplasm]

TP53 K291* [nucleoplasm]

TP53 T253Nfs*11 [nucleoplasm]

TP53 S183* [nucleoplasm]

TP53 A84Pfs*39 [nucleoplasm]

TP53 Q167Nfs*4 [nucleoplasm]

TP53 R213Ffs*35 [nucleoplasm]

TP53 H214Ifs*33 [nucleoplasm]

TP53 T253Qfs*3 [nucleoplasm]

TP53 N239Lfs*22 [nucleoplasm]

TP53 A189Pfs*58 [nucleoplasm]

TP53 P128Rfs*20 [nucleoplasm]

TP53 L130Pfs*41 [nucleoplasm]

TP53 V73Rfs*76 [nucleoplasm]

TP53 L252Sfs*93 [nucleoplasm]

TP53 Q192Afs*16 [nucleoplasm]

TP53 A129Rfs*38 [nucleoplasm]

TP53 C242Hfs*21 [nucleoplasm]

TP53 Y103Rfs*19 [nucleoplasm]

TP53 N131Pfs*19 [nucleoplasm]

TP53 K24Nfs*20 [nucleoplasm]

TP53 T140Dfs*9 [nucleoplasm]

TP53 R248Pfs*92 [nucleoplasm]

TP53 H179Pfs*2 [nucleoplasm]

TP53 C275Lfs*70 [nucleoplasm]

TP53 A138Pfs*32 [nucleoplasm]

TP53 Q144Ffs*32 [nucleoplasm]

TP53 P60Vfs*64 [nucleoplasm]

TP53 R249Sfs*96 [nucleoplasm]

TP53 Q165Sfs*5 [nucleoplasm]

TP53 R280Efs*65 [nucleoplasm]

TP53 V272Gfs*73 [nucleoplasm]

TP53 N311Qfs*26 [nucleoplasm]

TP53 L114Cfs*9 [nucleoplasm]

TP53 Y163Tfs*14 [nucleoplasm]

TP53 L252Pfs*92 [nucleoplasm]

TP53 C141Wfs*8 [nucleoplasm]

TP53 R209Kfs*6 [nucleoplasm]

TP53 G154Vfs*18 [nucleoplasm]

TP53 R202Afs*7 [nucleoplasm]

TP53 D207Gfs*8 [nucleoplasm]

TP53 D281Pfs*24 [nucleoplasm]

TP53 K120Qfs*29 [nucleoplasm]

TP53 K164Nfs*6 [nucleoplasm]

TP53 V73Afs*76 [nucleoplasm]

TP53 P77Qfs*46 [nucleoplasm]

TP53 Q165Hfs*5 [nucleoplasm]

TP53 Y163Tfs*7 [nucleoplasm]

TP53 E171Lfs*2 [nucleoplasm]

TP53 Q317Hfs*28 [nucleoplasm]

TP53 H168Rfs*5 [nucleoplasm]

TP53 N235Tfs*12 [nucleoplasm]

TP53 P153Hfs*26 [nucleoplasm]

TP53 E285Rfs*60 [nucleoplasm]

TP53 P152Rfs*27 [nucleoplasm]

TP53 L137Rfs*33 [nucleoplasm]

TP53 S260Qfs*3 [nucleoplasm]

TP53 A159Pfs*11 [nucleoplasm]

TP53 E171Mfs*61 [nucleoplasm]

TP53 E287Kfs*53 [nucleoplasm]

TP53 S149Yfs*31 [nucleoplasm]

TP53 G108Ffs*40 [nucleoplasm]

TP53 L201Ffs*8 [nucleoplasm]

TP53 P300Qfs*44 [nucleoplasm]

TP53 W53Cfs*4 [nucleoplasm]

TP53 I254Sfs*91 [nucleoplasm]

TP53 L35Ffs*8 [nucleoplasm]

TP53 V173Afs*6 [nucleoplasm]

TP53 G262Lfs*2 [nucleoplasm]

TP53 R175Afs*6 [nucleoplasm]

TP53 H168Qfs*2 [nucleoplasm]

TP53 M40Ifs*3 [nucleoplasm]

TP53 A189Pfs*19 [nucleoplasm]

TP53 E56Vfs*73 [nucleoplasm]

TP53 Y126Tfs*44 [nucleoplasm]

TP53 M133Sfs*37 [nucleoplasm]

TP53 A76Vfs*55 [nucleoplasm]

TP53 D49Yfs*2 [nucleoplasm]

TP53 P153Lfs*28 [nucleoplasm]

TP53 D184Rfs*2 [nucleoplasm]

TP53 R273Cfs*32 [nucleoplasm]

TP53 R213Tfs*2 [nucleoplasm]

TP53 L257Pfs*85 [nucleoplasm]

TP53 K292Rfs*13 [nucleoplasm]

TP53 G279Pfs*69 [nucleoplasm]

TP53 C141Sfs*26 [nucleoplasm]

TP53 N30Tfs*14 [nucleoplasm]

TP53 M169Ifs*5 [nucleoplasm]

TP53 S315Lfs*30 [nucleoplasm]

TP53 S33Ffs*10 [nucleoplasm]

TP53 Q167Lfs*2 [nucleoplasm]

TP53 Q144Gfs*2 [nucleoplasm]

TP53 G302Afs*42 [nucleoplasm]

TP53 S185Tfs*62 [nucleoplasm]

TP53 A138Cfs*27 [nucleoplasm]

TP53 R181Pfs*66 [nucleoplasm]

TP53 L206Ffs*35 [nucleoplasm]

TP53 E224Afs*2 [nucleoplasm]

TP53 Y126Sfs*44 [nucleoplasm]

TP53 C176Afs*71 [nucleoplasm]

TP53 T18Hfs*26 [nucleoplasm]

TP53 C277Vfs*68 [nucleoplasm]

TP53 C275Gfs*20 [nucleoplasm]

TP53 S241Wfs*19 [nucleoplasm]

TP53 G112Cfs*9 [nucleoplasm]

TP53 T155Pfs*23 [nucleoplasm]

TP53 D148* [nucleoplasm]

TP53 S121Ifs*28 [nucleoplasm]

TP53 K291Gfs*12 [nucleoplasm]

TP53 G108Rfs*41 [nucleoplasm]

TP53 D207Kfs*6 [nucleoplasm]

TP53 T125Afs*46 [nucleoplasm]

TP53 M243Wfs*4 [nucleoplasm]

TP53 A83Rfs*40 [nucleoplasm]

TP53 T211Lfs*36 [nucleoplasm]

TP53 Q167Hfs*3 [nucleoplasm]

TP53 Q38* [nucleoplasm]

TP53 R209Sfs*5 [nucleoplasm]

TP53 I254Tfs*7 [nucleoplasm]

TP53 L194Sfs*52 [nucleoplasm]

TP53 Q104* [nucleoplasm]

TP53 V122Dfs*26 [nucleoplasm]

TP53 G266Dfs*79 [nucleoplasm]

TP53 Y236* [nucleoplasm]

TP53 E298Dfs*7 [nucleoplasm]

TP53 D184Afs*62 [nucleoplasm]

TP53 M133Cfs*37 [nucleoplasm]

TP53 C229* [nucleoplasm]

TP53 R156Lfs*25 [nucleoplasm]

TP53 I162Wfs*10 [nucleoplasm]

TP53 H178Pfs*3 [nucleoplasm]

TP53 S20* [nucleoplasm]

TP53 K101* [nucleoplasm]

TP53 E62* [nucleoplasm]

TP53 S121Lfs*2 [nucleoplasm]

TP53 P222Sfs*26 [nucleoplasm]

TP53 E204* [nucleoplasm]

TP53 P316Sfs*21 [nucleoplasm]

TP53 Y103* [nucleoplasm]

TP53 T256Hfs*8 [nucleoplasm]

TP53 N288Ifs*18 [nucleoplasm]

TP53 T155Pfs*15 [nucleoplasm]

TP53 E258Gfs*6 [nucleoplasm]

TP53 P222Lfs*24 [nucleoplasm]

TP53 I50* [nucleoplasm]

TP53 L264Tfs*7 [nucleoplasm]

TP53 D207Afs*39 [nucleoplasm]

TP53 S99Rfs*23 [nucleoplasm]

TP53 N288Sfs*17 [nucleoplasm]

TP53 F270Lfs*72 [nucleoplasm]

TP53 A83Cfs*30 [nucleoplasm]

TP53 P60Qfs*63 [nucleoplasm]

TP53 K319Rfs*26 [nucleoplasm]

TP53 E298* [nucleoplasm]

TP53 R174* [nucleoplasm]

TP53 Y205Ifs*42 [nucleoplasm]

TP53 G154Afs*14 [nucleoplasm]

TP53 S315* [nucleoplasm]

TP53 D148Pfs*21 [nucleoplasm]

TP53 K292* [nucleoplasm]

TP53 E271* [nucleoplasm]

TP53 W53* [nucleoplasm]

TP53 R306Afs*31 [nucleoplasm]

TP53 K321* [nucleoplasm]

TP53 S127Pfs*43 [nucleoplasm]

TP53 P75Lfs*48 [nucleoplasm]

TP53 L32Pfs*11 [nucleoplasm]

TP53 I195Kfs*9 [nucleoplasm]

TP53 C277* [nucleoplasm]

TP53 L111Rfs*37 [nucleoplasm]

TP53 K305* [nucleoplasm]

TP53 P278Lfs*28 [nucleoplasm]

TP53 E51Gfs*6 [nucleoplasm]

TP53 D208Efs*7 [nucleoplasm]

TP53 R248* [nucleoplasm]

TP53 V218Wfs*30 [nucleoplasm]

TP53 R196Ffs*35 [nucleoplasm]

TP53 R280* [nucleoplasm]

TP53 V122Cfs*27 [nucleoplasm]

TP53 L114Cfs*30 [nucleoplasm]

TP53 G226Pfs*17 [nucleoplasm]

TP53 G112Afs*11 [nucleoplasm]

TP53 S227* [nucleoplasm]

TP53 I255Hfs*8 [nucleoplasm]

TP53 K164Sfs*5 [nucleoplasm]

TP53 C275Vfs*70 [nucleoplasm]

TP53 Q5* [nucleoplasm]

TP53 T256Nfs*8 [nucleoplasm]

TP53 N30Kfs*13 [nucleoplasm]

TP53 H168Tfs*69 [nucleoplasm]

TP53 P77Lfs*44 [nucleoplasm]

TP53 H179* [nucleoplasm]

TP53 C182* [nucleoplasm]

TP53 C135* [nucleoplasm]

TP53 Y163* [nucleoplasm]

TP53 R202Kfs*9 [nucleoplasm]

TP53 R156Lfs*18 [nucleoplasm]

TP53 I251Pfs*12 [nucleoplasm]

TP53 V218Gfs*30 [nucleoplasm]

TP53 D148Ffs*32 [nucleoplasm]

TP53 C229Vfs*18 [nucleoplasm]

TP53 C124Lfs*25 [nucleoplasm]

TP53 C141* [nucleoplasm]

TP53 N288Tfs*55 [nucleoplasm]

TP53 T125Rfs*45 [nucleoplasm]

TP53 H115Ffs*33 [nucleoplasm]

TP53 K139Rfs*31 [nucleoplasm]

TP53 I251Hfs*11 [nucleoplasm]

TP53 Y126* [nucleoplasm]

TP53 P36Afs*7 [nucleoplasm]

TP53 E180Afs*65 [nucleoplasm]

TP53 S166* [nucleoplasm]

TP53 T304Ifs*41 [nucleoplasm]

TP53 M237* [nucleoplasm]

TP53 L201* [nucleoplasm]

TP53 P82Afs*70 [nucleoplasm]

TP53 A78Gfs*73 [nucleoplasm]

TP53 K320* [nucleoplasm]

TP53 T170Lfs*2 [nucleoplasm]

TP53 E171Gfs*9 [nucleoplasm]

TP53 K291Qfs*15 [nucleoplasm]

TP53 M246Ifs*99 [nucleoplasm]

TP53 E198* [nucleoplasm]

TP53 P47Hfs*2 [nucleoplasm]

TP53 V218Cfs*29 [nucleoplasm]

TP53 P152Rfs*18 [nucleoplasm]

TP53 E258Kfs*87 [nucleoplasm]

TP53 G325* [nucleoplasm]

TP53 P71Wfs*50 [nucleoplasm]

TP53 N268* [nucleoplasm]

TP53 L93Ffs*53 [nucleoplasm]

TP53 D48Gfs*4 [nucleoplasm]

TP53 R248Qfs*15 [nucleoplasm]

TP53 E224* [nucleoplasm]

TP53 H179Qfs*64 [nucleoplasm]

TP53 G154Afs*16 [nucleoplasm]

TP53 Q192* [nucleoplasm]

TP53 G266* [nucleoplasm]

TP53 L188* [nucleoplasm]

TP53 T125Lfs*25 [nucleoplasm]

TP53 R65* [nucleoplasm]

TP53 M246Ifs*92 [nucleoplasm]

TP53 S215Ifs*36 [nucleoplasm]

TP53 C242* [nucleoplasm]

TP53 C124* [nucleoplasm]

TP53 N310Qfs*27 [nucleoplasm]

TP53 F54Lfs*69 [nucleoplasm]

TP53 E298Cfs*46 [nucleoplasm]

TP53 P223Rfs*4 [nucleoplasm]

TP53 Q317* [nucleoplasm]

TP53 I251Tfs*94 [nucleoplasm]

TP53 V157Sfs*13 [nucleoplasm]

TP53 R273Ffs*71 [nucleoplasm]

TP53 Q16* [nucleoplasm]

TP53 T284Ifs*57 [nucleoplasm]

TP53 Y327* [nucleoplasm]

TP53 R290Afs*55 [nucleoplasm]

TP53 N311Kfs*26 [nucleoplasm]

TP53 K319* [nucleoplasm]

TP53 V157Pfs*23 [nucleoplasm]

TP53 V143Rfs*6 [nucleoplasm]

TP53 P191Lfs*53 [nucleoplasm]

TP53 D61* [nucleoplasm]

TP53 G279Pfs*24 [nucleoplasm]

TP53 Q100* [nucleoplasm]

TP53 F54Sfs*69 [nucleoplasm]

TP53 L206Yfs*4 [nucleoplasm]

TP53 Y220* [nucleoplasm]

TP53 E68Rfs*55 [nucleoplasm]

TP53 P278Wfs*27 [nucleoplasm]

TP53 P223Lfs*24 [nucleoplasm]

TP53 R209* [nucleoplasm]

TP53 N288Qfs*15 [nucleoplasm]

TP53 Q52* [nucleoplasm]

TP53 S94Ffs*55 [nucleoplasm]

TP53 K132* [nucleoplasm]

TP53 L130Qfs*17 [nucleoplasm]

TP53 R174Mfs*68 [nucleoplasm]

TP53 W91Cfs*57 [nucleoplasm]

TP53 S269Gfs*34 [nucleoplasm]

TP53 Q144Hfs*26 [nucleoplasm]

TP53 C229Yfs*10 [nucleoplasm]

TP53 E180* [nucleoplasm]

TP53 W146* [nucleoplasm]

TP53 Q167Tfs*14 [nucleoplasm]

TP53 A276Vfs*68 [nucleoplasm]

TP53 V73Afs*51 [nucleoplasm]

TP53 V216Afs*28 [nucleoplasm]

TP53 T312Nfs*25 [nucleoplasm]

TP53 D186Mfs*61 [nucleoplasm]

TP53 P142Gfs*24 [nucleoplasm]

TP53 G293* [nucleoplasm]

TP53 L111Nfs*14 [nucleoplasm]

TP53 M133Dfs*16 [nucleoplasm]

TP53 H214Lfs*33 [nucleoplasm]

TP53 W91* [nucleoplasm]

TP53 P223Sfs*26 [nucleoplasm]

TP53 T211Ifs*33 [nucleoplasm]

TP53 A83Pfs*35 [nucleoplasm]

TP53 W23* [nucleoplasm]

TP53 L299Rfs*46 [nucleoplasm]

TP53 M40Lfs*7 [nucleoplasm]

TP53 R65Tfs*84 [nucleoplasm]

TP53 M133Pfs*13 [nucleoplasm]

TP53 S240Qfs*24 [nucleoplasm]

TP53 E204Wfs*44 [nucleoplasm]

TP53 M246* [nucleoplasm]

TP53 E221* [nucleoplasm]

TP53 G108Vfs*13 [nucleoplasm]

TP53 L206* [nucleoplasm]

TP53 N239* [nucleoplasm]

TP53 L299Hfs*2 [nucleoplasm]

TP53 M66Ifs*76 [nucleoplasm]

TP53 S215Ifs*33 [nucleoplasm]

TP53 Q38Sfs*4 [nucleoplasm]

TP53 S261* [nucleoplasm]

TP53 G244Rfs*19 [nucleoplasm]

TP53 E171* [nucleoplasm]

TP53 P152Afs*14 [nucleoplasm]

TP53 P13Lfs*2 [nucleoplasm]

TP53 R158Pfs*12 [nucleoplasm]

TP53 N210Ffs*35 [nucleoplasm]

TP53 K120Sfs*3 [nucleoplasm]

TP53 R175Pfs*72 [nucleoplasm]

TP53 G279Efs*26 [nucleoplasm]

TP53 E221Vfs*4 [nucleoplasm]

TP53 V173* [nucleoplasm]

TP53 P80Lfs*43 [nucleoplasm]

TP53 C176* [nucleoplasm]

TP53 N288Rfs*13 [nucleoplasm]

TP53 Q167Rfs*3 [nucleoplasm]

TP53 S149Ffs*32 [nucleoplasm]

TP53 P92Hfs*57 [nucleoplasm]

TP53 P72Lfs*48 [nucleoplasm]

TP53 G108Afs*34 [nucleoplasm]

TP53 N268Kfs*4 [nucleoplasm]

TP53 S46Pfs*77 [nucleoplasm]

TP53 P151Tfs*30 [nucleoplasm]

TP53 Q100Rfs*23 [nucleoplasm]

TP53 E285* [nucleoplasm]

TP53 E11* [nucleoplasm]

TP53 P71Sfs*78 [nucleoplasm]

TP53 L188Rfs*59 [nucleoplasm]

TP53 S240* [nucleoplasm]

TP53 S166Ifs*15 [nucleoplasm]

TP53 S37Cfs*79 [nucleoplasm]

TP53 W91Gfs*32 [nucleoplasm]

TP53 R158Sfs*8 [nucleoplasm]

TP53 R196* [nucleoplasm]

TP53 G154Pfs*28 [nucleoplasm]

TP53 L188Wfs*59 [nucleoplasm]

TP53 N239Tfs*8 [nucleoplasm]

TP53 L111Ifs*8 [nucleoplasm]

TP53 L206Ffs*42 [nucleoplasm]

TP53 A276Lfs*29 [nucleoplasm]

TP53 P87Qfs*36 [nucleoplasm]

TP53 K321Nfs*24 [nucleoplasm]

TP53 V217Gfs*30 [nucleoplasm]

TP53 S96Cfs*52 [nucleoplasm]

TP53 C242Lfs*22 [nucleoplasm]

TP53 C242Gfs*20 [nucleoplasm]

TP53 A189Dfs*14 [nucleoplasm]

TP53 A307Lfs*32 [nucleoplasm]

TP53 G187Vfs*60 [nucleoplasm]

TP53 V143Afs*21 [nucleoplasm]

TP53 S261Vfs*84 [nucleoplasm]

TP53 K291Tfs*48 [nucleoplasm]

TP53 F113Qfs*5 [nucleoplasm]

TP53 S215Cfs*29 [nucleoplasm]

TP53 N268Efs*4 [nucleoplasm]

TP53 V217Gfs*31 [nucleoplasm]

TP53 D148Efs*23 [nucleoplasm]

TP53 C242Hfs*18 [nucleoplasm]

TP53 S99Ffs*55 [nucleoplasm]

TP53 T284Rfs*19 [nucleoplasm]

TP53 V143Afs*5 [nucleoplasm]

TP53 F212Sfs*3 [nucleoplasm]

TP53 E198Ifs*47 [nucleoplasm]

TP53 L188Tfs*21 [nucleoplasm]

TP53 G112Lfs*7 [nucleoplasm]

TP53 V173Tfs*69 [nucleoplasm]

TP53 L93Afs*57 [nucleoplasm]

TP53 T253Sfs*91 [nucleoplasm]

TP53 L35Pfs*10 [nucleoplasm]

TP53 R248Gfs*97 [nucleoplasm]

TP53 M44Cfs*79 [nucleoplasm]

TP53 A69Gfs*80 [nucleoplasm]

TP53 P318Efs*16 [nucleoplasm]

TP53 V274Afs*33 [nucleoplasm]

TP53 L130Tfs*39 [nucleoplasm]

TP53 K292Lfs*54 [nucleoplasm]

TP53 Q317Afs*19 [nucleoplasm]

TP53 A86Vfs*55 [nucleoplasm]

TP53 Q136Wfs*33 [nucleoplasm]

TP53 V143Lfs*28 [nucleoplasm]

TP53 T81Pfs*49 [nucleoplasm]

TP53 M133Nfs*34 [nucleoplasm]

TP53 N29Kfs*14 [nucleoplasm]

TP53 A69Vfs*54 [nucleoplasm]

TP53 C277Lfs*67 [nucleoplasm]

TP53 V97Tfs*66 [nucleoplasm]

TP53 L14Sfs*15 [nucleoplasm]

TP53 L130Pfs*19 [nucleoplasm]

TP53 R290Qfs*15 [nucleoplasm]

TP53 I162Tfs*8 [nucleoplasm]

TP53 P190Sfs*12 [nucleoplasm]

TP53 E294Vfs*12 [nucleoplasm]

TP53 T304Qfs*44 [nucleoplasm]

TP53 N288Kfs*59 [nucleoplasm]

TP53 P85Cfs*63 [nucleoplasm]

TP53 E285Rfs*13 [nucleoplasm]

TP53 E298Sfs*47 [nucleoplasm]

TP53 S90Pfs*34 [nucleoplasm]

TP53 Q167Hfs*4 [nucleoplasm]

TP53 N210Tfs*7 [nucleoplasm]

TP53 P191Sfs*18 [nucleoplasm]

TP53 R290Lfs*50 [nucleoplasm]

TP53 N131Tfs*39 [nucleoplasm]

TP53 P177Lfs*3 [nucleoplasm]

TP53 I195Yfs*14 [nucleoplasm]

TP53 M44Sfs*79 [nucleoplasm]

TP53 V157Hfs*19 [nucleoplasm]

TP53 A159Hfs*21 [nucleoplasm]

TP53 N239Afs*5 [nucleoplasm]

TP53 E51Nfs*72 [nucleoplasm]

TP53 L265Tfs*7 [nucleoplasm]

TP53 E298Dfs*47 [nucleoplasm]

TP53 R282Afs*23 [nucleoplasm]

TP53 R175Lfs*5 [nucleoplasm]

TP53 N239Wfs*4 [nucleoplasm]

TP53 D281Afs*26 [nucleoplasm]

TP53 D208* [nucleoplasm]

TP53 F113Lfs*11 [nucleoplasm]

TP53 S94Ffs*28 [nucleoplasm]

TP53 A161Pfs*9 [nucleoplasm]

TP53 S33* [nucleoplasm]

TP53 L257Wfs*88 [nucleoplasm]

TP53 C229Yfs*8 [nucleoplasm]

TP53 R306* [nucleoplasm]

TP53 R213Vfs*32 [nucleoplasm]

TP53 D61Vfs*62 [nucleoplasm]

TP53 Q136* [nucleoplasm]

TP53 T230Sfs*11 [nucleoplasm]

TP53 D184Efs*64 [nucleoplasm]

TP53 C135Lfs*14 [nucleoplasm]

TP53 P152Afs*28 [nucleoplasm]

TP53 M246Rfs*19 [nucleoplasm]

TP53 L114* [nucleoplasm]

TP53 W146Vfs*3 [nucleoplasm]

TP53 S315Nfs*24 [nucleoplasm]

TP53 N200Vfs*4 [nucleoplasm]

TP53 A84Vfs*65 [nucleoplasm]

TP53 I162Vfs*15 [nucleoplasm]

TP53 P316Lfs*30 [nucleoplasm]

TP53 E286* [nucleoplasm]

TP53 F134Lfs*14 [nucleoplasm]

TP53 K139* [nucleoplasm]

TP53 H178Pfs*70 [nucleoplasm]

TP53 E51* [nucleoplasm]

TP53 E68* [nucleoplasm]

TP53 M66Nfs*83 [nucleoplasm]

TP53 Q165* [nucleoplasm]

TP53 T102Nfs*47 [nucleoplasm]

TP53 G154Afs*18 [nucleoplasm]

TP53 M243* [nucleoplasm]

TP53 T81Nfs*42 [nucleoplasm]

TP53 Y107* [nucleoplasm]

TP53 H297Lfs*9 [nucleoplasm]

TP53 E204Gfs*46 [nucleoplasm]

TP53 C275* [nucleoplasm]

TP53 R282Pfs*64 [nucleoplasm]

TP53 E258* [nucleoplasm]

TP53 P58Qfs*65 [nucleoplasm]

TP53 E198Wfs*44 [nucleoplasm]

TP53 D186* [nucleoplasm]

TP53 T150Hfs*20 [nucleoplasm]

TP53 M246Afs*19 [nucleoplasm]

TP53 P309Lfs*31 [nucleoplasm]

TP53 Q144* [nucleoplasm]

TP53 K164* [nucleoplasm]

TP53 H233Pfs*6 [nucleoplasm]

TP53 N247Rfs*97 [nucleoplasm]

TP53 Y234Tfs*11 [nucleoplasm]

TP53 D228Lfs*11 [nucleoplasm]

TP53 H168Rfs*4 [nucleoplasm]

TP53 Y234* [nucleoplasm]

TP53 K120* [nucleoplasm]

TP53 S303Efs*3 [nucleoplasm]

TP53 P190Lfs*53 [nucleoplasm]

TP53 S95Lfs*28 [nucleoplasm]

TP53 T211Pfs*28 [nucleoplasm]

TP53 P92Vfs*55 [nucleoplasm]

TP53 Y205Sfs*4 [nucleoplasm]

TP53 P295Lfs*50 [nucleoplasm]

TP53 R283Lfs*23 [nucleoplasm]

TP53 R282Gfs*63 [nucleoplasm]

TP53 G245Afs*14 [nucleoplasm]

TP53 L32Cfs*12 [nucleoplasm]

TP53 A83Pfs*39 [nucleoplasm]

TP53 L130Pfs*39 [nucleoplasm]

TP53 S33Vfs*6 [nucleoplasm]

TP53 Q167* [nucleoplasm]

TP53 S227Vfs*2 [nucleoplasm]

TP53 V173Efs*7 [nucleoplasm]

TP53 K292Nfs*7 [nucleoplasm]

TP53 D49Efs*3 [nucleoplasm]

TP53 Y205* [nucleoplasm]

TP53 C238* [nucleoplasm]

TP53 F109Sfs*38 [nucleoplasm]

TP53 E56Kfs*67 [nucleoplasm]

TP53 F113Sfs*10 [nucleoplasm]

TP53 V143Afs*29 [nucleoplasm]

TP53 P222Gfs*4 [nucleoplasm]

TP53 Q144Cfs*25 [nucleoplasm]

TP53 A83Gfs*66 [nucleoplasm]

TP53 M66Sfs*57 [nucleoplasm]

TP53 P87Ifs*54 [nucleoplasm]

TP53 G117Wfs*32 [nucleoplasm]

TP53 A86Gfs*63 [nucleoplasm]

TP53 R158Hfs*21 [nucleoplasm]

TP53 R249Gfs*96 [nucleoplasm]

TP53 P301Rfs*4 [nucleoplasm]

TP53 D41Gfs*2 [nucleoplasm]

TP53 R283Kfs*59 [nucleoplasm]

TP53 T123Rfs*48 [nucleoplasm]

TP53 T231Pfs*16 [nucleoplasm]

TP53 N288Ifs*57 [nucleoplasm]

TP53 E286Kfs*59 [nucleoplasm]

TP53 Q100Gfs*37 [nucleoplasm]

TP53 N210Kfs*6 [nucleoplasm]

TP53 G226Afs*21 [nucleoplasm]

TP53 D184Efs*24 [nucleoplasm]

TP53 P87Lfs*59 [nucleoplasm]

TP53 K164Sfs*3 [nucleoplasm]

TP53 W91Cfs*32 [nucleoplasm]

TP53 E285Rfs*54 [nucleoplasm]

TP53 A138Gfs*11 [nucleoplasm]

TP53 R196Ffs*8 [nucleoplasm]

TP53 Q136Nfs*34 [nucleoplasm]

TP53 C124Afs*46 [nucleoplasm]

TP53 P153Sfs*28 [nucleoplasm]

TP53 L299Afs*7 [nucleoplasm]

TP53 S269Tfs*76 [nucleoplasm]

TP53 D41Mfs*3 [nucleoplasm]

TP53 H115Ifs*8 [nucleoplasm]

TP53 E180Sfs*67 [nucleoplasm]

TP53 P67Rfs*81 [nucleoplasm]

TP53 Q104Pfs*45 [nucleoplasm]

TP53 G245Vfs*19 [nucleoplasm]

TP53 D228Tfs*12 [nucleoplasm]

TP53 L201Cfs*46 [nucleoplasm]

TP53 Y163Hfs*4 [nucleoplasm]

TP53 M237Cfs*10 [nucleoplasm]

TP53 P72Rfs*76 [nucleoplasm]

TP53 V122Hfs*24 [nucleoplasm]

TP53 R209Kfs*38 [nucleoplasm]

TP53 A88Gfs*44 [nucleoplasm]

TP53 N311Tfs*34 [nucleoplasm]

TP53 D208Efs*38 [nucleoplasm]

TP53 Q165Hfs*4 [nucleoplasm]

TP53 L252Pfs*12 [nucleoplasm]

TP53 H214Qfs*2 [nucleoplasm]

TP53 D207Ffs*3 [nucleoplasm]

TP53 G59Qfs*84 [nucleoplasm]

TP53 E51Dfs*72 [nucleoplasm]

TP53 S127Lfs*42 [nucleoplasm]

TP53 E68Rfs*81 [nucleoplasm]

TP53 P77Cfs*73 [nucleoplasm]

TP53 Q38Wfs*4 [nucleoplasm]

TP53 Q136Sfs*13 [nucleoplasm]

TP53 D57Vfs*64 [nucleoplasm]

TP53 S149Pfs*17 [nucleoplasm]

TP53 R290Gfs*12 [nucleoplasm]

TP53 S261Tfs*2 [nucleoplasm]

TP53 V274Ffs*71 [nucleoplasm]

TP53 V157Rfs*22 [nucleoplasm]

TP53 A78Yfs*68 [nucleoplasm]

TP53 R273Vfs*72 [nucleoplasm]

TP53 M133Ifs*36 [nucleoplasm]

TP53 A88Sfs*61 [nucleoplasm]

TP53 R306Efs*39 [nucleoplasm]

TP53 F19Ifs*10 [nucleoplasm]

TP53 P142Lfs*28 [nucleoplasm]

TP53 T102Pfs*21 [nucleoplasm]

TP53 E287Sfs*17 [nucleoplasm]

TP53 H168Rfs*23 [nucleoplasm]

TP53 Y163Lfs*18 [nucleoplasm]

TP53 R158Sfs*23 [nucleoplasm]

TP53 H168Pfs*2 [nucleoplasm]

TP53 A84Gfs*65 [nucleoplasm]

TP53 L111Ffs*40 [nucleoplasm]

TP53 R158Afs*12 [nucleoplasm]

TP53 S269Cfs*32 [nucleoplasm]

TP53 T81Nfs*68 [nucleoplasm]

TP53 R156Sfs*8 [nucleoplasm]

TP53 G244Efs*17 [nucleoplasm]

TP53 C277Ffs*68 [nucleoplasm]

TP53 P27Lfs*17 [nucleoplasm]

TP53 G244Afs*3 [nucleoplasm]

TP53 H233Vfs*8 [nucleoplasm]

TP53 G245Efs*17 [nucleoplasm]

TP53 C238Hfs*21 [nucleoplasm]

TP53 P142Afs*7 [nucleoplasm]

TP53 L194Hfs*14 [nucleoplasm]

TP53 N268Tfs*77 [nucleoplasm]

TP53 L130Cfs*20 [nucleoplasm]

TP53 L201Afs*7 [nucleoplasm]

TP53 S215Kfs*7 [nucleoplasm]

TP53 R65Qfs*84 [nucleoplasm]

TP53 K101Lfs*42 [nucleoplasm]

TP53 S269Rfs*21 [nucleoplasm]

TP53 S106Vfs*15 [nucleoplasm]

TP53 R110Sfs*14 [nucleoplasm]

TP53 A161Sfs*8 [nucleoplasm]

TP53 M66Qfs*56 [nucleoplasm]

TP53 A129Pfs*42 [nucleoplasm]

TP53 A74Sfs*71 [nucleoplasm]

TP53 E224Gfs*4 [nucleoplasm]

TP53 K120Mfs*25 [nucleoplasm]

TP53 P151Rfs*27 [nucleoplasm]

TP53 V216Gfs*31 [nucleoplasm]

TP53 T125Ifs*47 [nucleoplasm]

TP53 S227Lfs*20 [nucleoplasm]

TP53 G244Tfs*19 [nucleoplasm]

TP53 A161Tfs*7 [nucleoplasm]

TP53 P34Lfs*8 [nucleoplasm]

TP53 R209Lfs*36 [nucleoplasm]

TP53 W146Ifs*22 [nucleoplasm]

TP53 K319Nfs*18 [nucleoplasm]

TP53 D228Tfs*19 [nucleoplasm]

TP53 V73Gfs*50 [nucleoplasm]

TP53 S240Ffs*23 [nucleoplasm]

TP53 I255Sfs*90 [nucleoplasm]

TP53 S116Vfs*23 [nucleoplasm]

TP53 L206Wfs*41 [nucleoplasm]

TP53 L22Yfs*22 [nucleoplasm]

TP53 L257Gfs*6 [nucleoplasm]

TP53 T140Cfs*6 [nucleoplasm]

TP53 N268Qfs*3 [nucleoplasm]

TP53 Q165Hfs*17 [nucleoplasm]

TP53 D281Tfs*64 [nucleoplasm]

TP53 A39Mfs*3 [nucleoplasm]

TP53 A307Tfs*29 [nucleoplasm]

TP53 R283Hfs*22 [nucleoplasm]

TP53 P153Afs*28 [nucleoplasm]

TP53 Q52Kfs*67 [nucleoplasm]

TP53 R273Lfs*33 [nucleoplasm]

TP53 L93Vfs*55 [nucleoplasm]

TP53 T118Gfs*6 [nucleoplasm]

TP53 N263Tfs*7 [nucleoplasm]

TP53 M66Gfs*80 [nucleoplasm]

TP53 E56Rfs*6 [nucleoplasm]

TP53 P278Lfs*68 [nucleoplasm]

TP53 K291Nfs*49 [nucleoplasm]

TP53 D57Sfs*86 [nucleoplasm]

TP53 Y126Qfs*18 [nucleoplasm]

TP53 D57Tfs*72 [nucleoplasm]

TP53 S149Hfs*31 [nucleoplasm]

TP53 Y234Ifs*6 [nucleoplasm]

TP53 Q136Pfs*30 [nucleoplasm]

TP53 Q136Sfs*26 [nucleoplasm]

TP53 P128Tfs*21 [nucleoplasm]

TP53 L188Pfs*58 [nucleoplasm]

TP53 S94Pfs*24 [nucleoplasm]

TP53 I195Pfs*13 [nucleoplasm]

TP53 C141Afs*29 [nucleoplasm]

TP53 R209Hfs*5 [nucleoplasm]

TP53 S315Wfs*22 [nucleoplasm]

TP53 P98Lfs*25 [nucleoplasm]

TP53 L264Yfs*81 [nucleoplasm]

TP53 R267Efs*65 [nucleoplasm]

TP53 A74Pfs*49 [nucleoplasm]

TP53 R283Afs*62 [nucleoplasm]

TP53 P128Tfs*12 [nucleoplasm]

TP53 V218Gfs*4 [nucleoplasm]

TP53 R174Sfs*73 [nucleoplasm]

TP53 T231Ffs*15 [nucleoplasm]

TP53 R306Lfs*32 [nucleoplasm]

TP53 T155Hfs*21 [nucleoplasm]

TP53 Q167Hfs*12 [nucleoplasm]

TP53 S215Vfs*32 [nucleoplasm]

TP53 A86Cfs*63 [nucleoplasm]

TP53 D208Ffs*42 [nucleoplasm]

TP53 L265Pfs*5 [nucleoplasm]

TP53 C124Ffs*47 [nucleoplasm]

TP53 V97Lfs*25 [nucleoplasm]

TP53 Q52Lfs*68 [nucleoplasm]

TP53 R181Lfs*4 [nucleoplasm]

TP53 P153Afs*16 [nucleoplasm]

TP53 S95Ifs*54 [nucleoplasm]

TP53 V147Rfs*27 [nucleoplasm]

TP53 A129Pfs*41 [nucleoplasm]

TP53 C141Afs*5 [nucleoplasm]

TP53 T230Lfs*6 [nucleoplasm]

TP53 G226Dfs*3 [nucleoplasm]

TP53 N210Tfs*37 [nucleoplasm]

TP53 V272Cfs*73 [nucleoplasm]

TP53 V173Rfs*23 [nucleoplasm]

TP53 A84Pfs*35 [nucleoplasm]

TP53 G154Pfs*25 [nucleoplasm]

TP53 Y107Tfs*16 [nucleoplasm]

TP53 P58Rfs*6 [nucleoplasm]

TP53 I195Wfs*50 [nucleoplasm]

TP53 F109Sfs*14 [nucleoplasm]

TP53 C275Lfs*67 [nucleoplasm]

TP53 Y103Vfs*15 [nucleoplasm]

TP53 E221Sfs*26 [nucleoplasm]

TP53 Y236Tfs*11 [nucleoplasm]

TP53 V143Afs*4 [nucleoplasm]

TP53 A86Gfs*32 [nucleoplasm]

TP53 C242Tfs*98 [nucleoplasm]

TP53 V73Rfs*51 [nucleoplasm]

TP53 P142Afs*5 [nucleoplasm]

TP53 L308Pfs*15 [nucleoplasm]

TP53 N310Kfs*27 [nucleoplasm]

TP53 S240Kfs*24 [nucleoplasm]

TP53 V272Afs*33 [nucleoplasm]

TP53 C176Mfs*68 [nucleoplasm]

TP53 R110Vfs*13 [nucleoplasm]

TP53 S96Lfs*27 [nucleoplasm]

TP53 R158Pfs*11 [nucleoplasm]

TP53 C135Afs*35 [nucleoplasm]

TP53 H179Lfs*68 [nucleoplasm]

TP53 N263Ifs*82 [nucleoplasm]

TP53 L26Qfs*13 [nucleoplasm]

TP53 Q100Sfs*54 [nucleoplasm]

TP53 W146Lfs*23 [nucleoplasm]

TP53 G302Vfs*44 [nucleoplasm]

TP53 P85Lfs*38 [nucleoplasm]

TP53 A39Qfs*5 [nucleoplasm]

TP53 E294Sfs*51 [nucleoplasm]

TP53 K139Afs*4 [nucleoplasm]

TP53 P309Qfs*26 [nucleoplasm]

TP53 S215Mfs*27 [nucleoplasm]

TP53 D281Efs*26 [nucleoplasm]

TP53 T123Dfs*26 [nucleoplasm]

TP53 R110Wfs*12 [nucleoplasm]

TP53 V97Sfs*26 [nucleoplasm]

TP53 Y205Ffs*8 [nucleoplasm]

TP53 V203Wfs*44 [nucleoplasm]

TP53 S314Lfs*22 [nucleoplasm]

TP53 L257Hfs*89 [nucleoplasm]

TP53 T284Qfs*61 [nucleoplasm]

TP53 F270Vfs*72 [nucleoplasm]

TP53 A129Cfs*20 [nucleoplasm]

TP53 N263Tfs*8 [nucleoplasm]

TP53 K319Afs*19 [nucleoplasm]

TP53 D324Rfs*13 [nucleoplasm]

TP53 S183Tfs*65 [nucleoplasm]

TP53 V157Afs*24 [nucleoplasm]

TP53 R267Tfs*5 [nucleoplasm]

TP53 G262Wfs*80 [nucleoplasm]

TP53 G245Pfs*16 [nucleoplasm]

TP53 N247Tfs*98 [nucleoplasm]

TP53 R110Lfs*13 [nucleoplasm]

TP53 K320Rfs*25 [nucleoplasm]

TP53 N131Cfs*27 [nucleoplasm]

TP53 K139Dfs*9 [nucleoplasm]

TP53 T230Pfs*17 [nucleoplasm]

TP53 R273Cfs*73 [nucleoplasm]

TP53 G154Wfs*10 [nucleoplasm]

TP53 G302Rfs*4 [nucleoplasm]

TP53 P278Lfs*67 [nucleoplasm]

TP53 E198Gfs*11 [nucleoplasm]

TP53 T150Afs*16 [nucleoplasm]

TP53 S106Qfs*43 [nucleoplasm]

TP53 A189Gfs*20 [nucleoplasm]

TP53 R280Afs*62 [nucleoplasm]

TP53 H297Pfs*48 [nucleoplasm]

TP53 D324Vfs*21 [nucleoplasm]

TP53 M237Sfs*10 [nucleoplasm]

TP53 S149Afs*72 [nucleoplasm]

TP53 G112Lfs*36 [nucleoplasm]

TP53 T155Afs*28 [nucleoplasm]

TP53 I255Nfs*9 [nucleoplasm]

TP53 P128Lfs*42 [nucleoplasm]

TP53 D148Ifs*22 [nucleoplasm]

TP53 R65Kfs*84 [nucleoplasm]

TP53 L257Hfs*9 [nucleoplasm]

TP53 D207Lfs*41 [nucleoplasm]

TP53 P295Rfs*12 [nucleoplasm]

TP53 Y103Lfs*42 [nucleoplasm]

TP53 F113Pfs*37 [nucleoplasm]

TP53 D208Afs*39 [nucleoplasm]

TP53 R213Dfs*34 [nucleoplasm]

TP53 R209Ffs*35 [nucleoplasm]

TP53 T150Nfs*20 [nucleoplasm]

TP53 W146Pfs*19 [nucleoplasm]

TP53 D259Afs*86 [nucleoplasm]

TP53 Y220Lfs*2 [nucleoplasm]

TP53 H178Pfs*2 [nucleoplasm]

TP53 E285Rfs*21 [nucleoplasm]

TP53 T81Sfs*43 [nucleoplasm]

TP53 M133Rfs*38 [nucleoplasm]

TP53 L323Wfs*22 [nucleoplasm]

TP53 L308Afs*6 [nucleoplasm]

TP53 K291Rfs*54 [nucleoplasm]

TP53 I50Nfs*72 [nucleoplasm]

TP53 Q144Afs*4 [nucleoplasm]

TP53 R110Pfs*39 [nucleoplasm]

TP53 P85Lfs*58 [nucleoplasm]

TP53 S241Pfs*6 [nucleoplasm]

TP53 S90Pfs*33 [nucleoplasm]

TP53 Y205Lfs*4 [nucleoplasm]

TP53 A129Vfs*20 [nucleoplasm]

TP53 S314Rfs*25 [nucleoplasm]

TP53 H233Lfs*6 [nucleoplasm]

TP53 P82Rfs*41 [nucleoplasm]

TP53 I232Qfs*5 [nucleoplasm]

TP53 T55Mfs*68 [nucleoplasm]

TP53 G245Afs*2 [nucleoplasm]

TP53 H296Rfs*8 [nucleoplasm]

TP53 S269Kfs*3 [nucleoplasm]

TP53 G293Rfs*13 [nucleoplasm]

TP53 T118Qfs*5 [nucleoplasm]

TP53 T118Nfs*31 [nucleoplasm]

TP53 P36Tfs*75 [nucleoplasm]

TP53 P92Afs*57 [nucleoplasm]

TP53 N239Kfs*15 [nucleoplasm]

TP53 T140Mfs*28 [nucleoplasm]

TP53 A88Gfs*32 [nucleoplasm]

TP53 T256Hfs*89 [nucleoplasm]

TP53 N288Kfs*18 [nucleoplasm]

TP53 P152Hfs*29 [nucleoplasm]

TP53 N288Efs*14 [nucleoplasm]

TP53 S94Yfs*29 [nucleoplasm]

TP53 Q136Pfs*13 [nucleoplasm]

TP53 T231Nfs*9 [nucleoplasm]

TP53 V157Hfs*21 [nucleoplasm]

TP53 K320Efs*17 [nucleoplasm]

TP53 N263Tfs*5 [nucleoplasm]

TP53 T118Dfs*31 [nucleoplasm]

TP53 T170Sfs*8 [nucleoplasm]

TP53 R283Sfs*56 [nucleoplasm]

TP53 R290Kfs*53 [nucleoplasm]

TP53 S227Hfs*9 [nucleoplasm]

TP53 S240Vfs*7 [nucleoplasm]

TP53 R280Tfs*64 [nucleoplasm]

TP53 C124Wfs*25 [nucleoplasm]

TP53 R196Efs*51 [nucleoplasm]

TP53 S99Pfs*24 [nucleoplasm]

TP53 L130Dfs*16 [nucleoplasm]

TP53 L43Cfs*9 [nucleoplasm]

TP53 D148Pfs*23 [nucleoplasm]

TP53 M160Wfs*10 [nucleoplasm]

TP53 D42Qfs*5 [nucleoplasm]

TP53 L93Cfs*30 [nucleoplasm]

TP53 E271Gfs*34 [nucleoplasm]

TP53 Y220Mfs*27 [nucleoplasm]

TP53 Q144Afs*16 [nucleoplasm]

TP53 R65Cfs*79 [nucleoplasm]

TP53 F109Gfs*37 [nucleoplasm]

TP53 H214Qfs*7 [nucleoplasm]

TP53 C135Sfs*35 [nucleoplasm]

TP53 C124Yfs*24 [nucleoplasm]

TP53 R283Pfs*16 [nucleoplasm]

TP53 Q192Sfs*55 [nucleoplasm]

TP53 W53Yfs*2 [nucleoplasm]

TP53 P219Afs*3 [nucleoplasm]

TP53 R213Sfs*3 [nucleoplasm]

TP53 L26Pfs*11 [nucleoplasm]

TP53 H168Rfs*3 [nucleoplasm]

TP53 Y234Qfs*5 [nucleoplasm]

TP53 P190Lfs*57 [nucleoplasm]

TP53 H233Tfs*14 [nucleoplasm]

TP53 K132Rfs*38 [nucleoplasm]

TP53 L137Wfs*33 [nucleoplasm]

TP53 R156Afs*14 [nucleoplasm]

TP53 N235Lfs*4 [nucleoplasm]

TP53 E221Gfs*26 [nucleoplasm]

TP53 V143Cfs*27 [nucleoplasm]

TP53 S313Afs*32 [nucleoplasm]

TP53 A189Vfs*53 [nucleoplasm]

TP53 R267Gfs*78 [nucleoplasm]

TP53 H193Qfs*48 [nucleoplasm]

TP53 V143Gfs*2 [nucleoplasm]

TP53 W53Gfs*70 [nucleoplasm]

TP53 S241Lfs*22 [nucleoplasm]

TP53 K291Sfs*51 [nucleoplasm]

TP53 R156Hfs*26 [nucleoplasm]

TP53 A307Sfs*30 [nucleoplasm]

TP53 Q100Lfs*42 [nucleoplasm]

TP53 L45Vfs*6 [nucleoplasm]

TP53 N310Kfs*26 [nucleoplasm]

TP53 M66Tfs*60 [nucleoplasm]

TP53 S215Wfs*31 [nucleoplasm]

TP53 M44Afs*7 [nucleoplasm]

TP53 Y103Lfs*46 [nucleoplasm]

TP53 A88Pfs*35 [nucleoplasm]

TP53 G279Efs*65 [nucleoplasm]

TP53 H214Cfs*29 [nucleoplasm]

TP53 P222Rfs*25 [nucleoplasm]

TP53 P177Tfs*69 [nucleoplasm]

TP53 M133Ifs*12 [nucleoplasm]

TP53 A74Qfs*45 [nucleoplasm]

TP53 R174Kfs*24 [nucleoplasm]

TP53 P82Gfs*66 [nucleoplasm]

TP53 N310Tfs*35 [nucleoplasm]

TP53 S215Cfs*6 [nucleoplasm]

TP53 L114Ffs*33 [nucleoplasm]

TP53 L265Wfs*80 [nucleoplasm]

TP53 I195Lfs*53 [nucleoplasm]

TP53 R249Afs*14 [nucleoplasm]

TP53 A69Lfs*54 [nucleoplasm]

TP53 S96Yfs*53 [nucleoplasm]

TP53 S227Wfs*3 [nucleoplasm]

TP53 Q144Hfs*4 [nucleoplasm]

TP53 P152Rfs*24 [nucleoplasm]

TP53 V73Lfs*43 [nucleoplasm]

TP53 H178Qfs*3 [nucleoplasm]

TP53 Y107Tfs*44 [nucleoplasm]

TP53 S94Ifs*54 [nucleoplasm]

TP53 V225Gfs*20 [nucleoplasm]

TP53 P47Gfs*4 [nucleoplasm]

TP53 G302Hfs*2 [nucleoplasm]

TP53 V147Lfs*23 [nucleoplasm]

TP53 T102Pfs*45 [nucleoplasm]

TP53 F341L [nucleoplasm]

TP53 R174Gfs*73 [nucleoplasm]

TP53 P67Lfs*54 [nucleoplasm]

TP53 E285Gfs*20 [nucleoplasm]

TP53 C182Afs*65 [nucleoplasm]

TP53 G154Rfs*22 [nucleoplasm]

TP53 P36Rfs*8 [nucleoplasm]

TP53 F341V [nucleoplasm]

TP53 F341S [nucleoplasm]

TP53 I50Mfs*73 [nucleoplasm]

TP53 L308Sfs*30 [nucleoplasm]

TP53 Q165Afs*6 [nucleoplasm]

TP53 D259Rfs*5 [nucleoplasm]

TP53 G154Rfs*27 [nucleoplasm]

TP53 K351* [nucleoplasm]

TP53 L264Hfs*81 [nucleoplasm]

TP53 Q354* [nucleoplasm]

TP53 I232Sfs*15 [nucleoplasm]

TP53 E294Gfs*12 [nucleoplasm]

TP53 S106Gfs*44 [nucleoplasm]

TP53 D228Vfs*18 [nucleoplasm]

TP53 H214Rfs*25 [nucleoplasm]

TP53 E171Rfs*3 [nucleoplasm]

TP53 Y103Gfs*44 [nucleoplasm]

TP53 E294Afs*11 [nucleoplasm]

TP53 A161Gfs*20 [nucleoplasm]

TP53 T312Pfs*20 [nucleoplasm]

TP53 E62Kfs*65 [nucleoplasm]

TP53 T55Pfs*52 [nucleoplasm]

TP53 K351N [nucleoplasm]

TP53 Y103Tfs*20 [nucleoplasm]

TP53 S313Pfs*33 [nucleoplasm]

TP53 Y107Sfs*38 [nucleoplasm]

TP53 G199Rfs*10 [nucleoplasm]

TP53 Y205Tfs*37 [nucleoplasm]

TP53 K351R [nucleoplasm]

TP53 N311Kfs*34 [nucleoplasm]

TP53 P190Sfs*17 [nucleoplasm]

TP53 G187Afs*21 [nucleoplasm]

TP53 L264Sfs*8 [nucleoplasm]

TP53 P98Yfs*26 [nucleoplasm]

TP53 G105Afs*18 [nucleoplasm]

TP53 D259Qfs*3 [nucleoplasm]

TP53 A86Lfs*59 [nucleoplasm]

TP53 M133Lfs*42 [nucleoplasm]

TP53 P80Rfs*41 [nucleoplasm]

TP53 E204Wfs*41 [nucleoplasm]

TP53 L299Afs*6 [nucleoplasm]

TP53 R249Kfs*15 [nucleoplasm]

TP53 G59Vfs*64 [nucleoplasm]

TP53 S90Lfs*59 [nucleoplasm]

TP53 W91Vfs*13 [nucleoplasm]

TP53 N210Hfs*5 [nucleoplasm]

TP53 S95Ffs*53 [nucleoplasm]

TP53 G108Vfs*15 [nucleoplasm]

TP53 P191Sfs*15 [nucleoplasm]

TP53 R196Sfs*12 [nucleoplasm]

TP53 P153Sfs*13 [nucleoplasm]

TP53 E204Vfs*4 [nucleoplasm]

TP53 Q317Rfs*28 [nucleoplasm]

TP53 D184Vfs*63 [nucleoplasm]

TP53 Q52Nfs*71 [nucleoplasm]

TP53 Y220Hfs*5 [nucleoplasm]

TP53 S20Qfs*24 [nucleoplasm]

TP53 A307Rfs*39 [nucleoplasm]

TP53 T256Nfs*89 [nucleoplasm]

TP53 H297Sfs*10 [nucleoplasm]

TP53 F270Lfs*2 [nucleoplasm]

TP53 H115Qfs*4 [nucleoplasm]

TP53 I195Nfs*14 [nucleoplasm]

TP53 Q136Hfs*34 [nucleoplasm]

TP53 R283Sfs*23 [nucleoplasm]

TP53 T140Pfs*30 [nucleoplasm]

TP53 A161Dfs*19 [nucleoplasm]

TP53 S260Lfs*4 [nucleoplasm]

TP53 N288Kfs*15 [nucleoplasm]

TP53 T155Hfs*26 [nucleoplasm]

TP53 S15Rfs*28 [nucleoplasm]

TP53 R280Sfs*66 [nucleoplasm]

TP53 C275Lfs*31 [nucleoplasm]

TP53 C182Afs*66 [nucleoplasm]

TP53 P128Qfs*17 [nucleoplasm]

TP53 A347P [nucleoplasm]

TP53 I195Mfs*13 [nucleoplasm]

TP53 A347D [nucleoplasm]

TP53 R290Sfs*56 [nucleoplasm]

TP53 Q52Hfs*71 [nucleoplasm]

TP53 S269Rfs*74 [nucleoplasm]

TP53 G199Efs*48 [nucleoplasm]

TP53 S95Hfs*29 [nucleoplasm]

TP53 S94Hfs*29 [nucleoplasm]

TP53 P85Hfs*37 [nucleoplasm]

TP53 A189Cfs*20 [nucleoplasm]

TP53 D324Afs*29 [nucleoplasm]

TP53 H296Tfs*49 [nucleoplasm]

TP53 V203Gfs*5 [nucleoplasm]

TP53 R248Pfs*16 [nucleoplasm]

TP53 R209Cfs*6 [nucleoplasm]

TP53 A307Gfs*30 [nucleoplasm]

TP53 M237Vfs*9 [nucleoplasm]

TP53 R110Qfs*15 [nucleoplasm]

TP53 P301Lfs*41 [nucleoplasm]

TP53 L45Pfs*5 [nucleoplasm]

TP53 P152Lfs*29 [nucleoplasm]

TP53 V225Wfs*3 [nucleoplasm]

TP53 K132Cfs*37 [nucleoplasm]

TP53 M160Rfs*10 [nucleoplasm]

TP53 T304Lfs*3 [nucleoplasm]

TP53 A119Sfs*3 [nucleoplasm]

TP53 A276Lfs*31 [nucleoplasm]

TP53 T170Rfs*4 [nucleoplasm]

TP53 T123Ifs*47 [nucleoplasm]

TP53 V157Rfs*24 [nucleoplasm]

TP53 P316Lfs*21 [nucleoplasm]

TP53 A74Gfs*75 [nucleoplasm]

TP53 T304Yfs*2 [nucleoplasm]

TP53 Q167Afs*13 [nucleoplasm]

TP53 E221Afs*2 [nucleoplasm]

TP53 P82Hfs*42 [nucleoplasm]

TP53 G199Ifs*42 [nucleoplasm]

TP53 P77Sfs*71 [nucleoplasm]

TP53 K320Mfs*21 [nucleoplasm]

TP53 Y163Qfs*17 [nucleoplasm]

TP53 D208Ffs*35 [nucleoplasm]

TP53 P153Rfs*22 [nucleoplasm]

TP53 V172Lfs*2 [nucleoplasm]

TP53 A63Lfs*60 [nucleoplasm]

TP53 T256Kfs*87 [nucleoplasm]

TP53 N288Afs*55 [nucleoplasm]

TP53 D281Efs*18 [nucleoplasm]

TP53 A119Rfs*6 [nucleoplasm]

TP53 A70Rfs*76 [nucleoplasm]

TP53 H297Tfs*48 [nucleoplasm]

TP53 T118Cfs*27 [nucleoplasm]

TP53 R156Pfs*14 [nucleoplasm]

TP53 V225Lfs*22 [nucleoplasm]

TP53 L289Pfs*56 [nucleoplasm]

TP53 C176Afs*65 [nucleoplasm]

TP53 R65Efs*58 [nucleoplasm]

TP53 Y107Vfs*13 [nucleoplasm]

TP53 I195Sfs*12 [nucleoplasm]

TP53 S215Mfs*32 [nucleoplasm]

TP53 S127Ffs*36 [nucleoplasm]

TP53 V157Wfs*10 [nucleoplasm]

TP53 S183Rfs*2 [nucleoplasm]

TP53 L93Rfs*30 [nucleoplasm]

TP53 T284Rfs*21 [nucleoplasm]

TP53 S313Lfs*45 [nucleoplasm]

TP53 P75Yfs*68 [nucleoplasm]

TP53 S95Gfs*37 [nucleoplasm]

TP53 T211Ffs*4 [nucleoplasm]

TP53 N131Kfs*39 [nucleoplasm]

TP53 Y103Efs*23 [nucleoplasm]

TP53 L145Afs*4 [nucleoplasm]

TP53 H214Gfs*5 [nucleoplasm]

TP53 V157Pfs*9 [nucleoplasm]

TP53 D207Efs*6 [nucleoplasm]

TP53 P322Tfs*15 [nucleoplasm]

TP53 R156Afs*12 [nucleoplasm]

TP53 D21Tfs*23 [nucleoplasm]

TP53 V218Sfs*26 [nucleoplasm]

TP53 S106Rfs*16 [nucleoplasm]

TP53 A138Pfs*30 [nucleoplasm]

TP53 W91Cfs*52 [nucleoplasm]

TP53 G244Afs*4 [nucleoplasm]

TP53 S46Vfs*6 [nucleoplasm]

TP53 R273Lfs*72 [nucleoplasm]

TP53 S185Afs*62 [nucleoplasm]

TP53 Q144Pfs*5 [nucleoplasm]

TP53 Y234Sfs*15 [nucleoplasm]

TP53 Q144Sfs*26 [nucleoplasm]

TP53 N239Kfs*22 [nucleoplasm]

TP53 P191Yfs*14 [nucleoplasm]

TP53 I50Mfs*4 [nucleoplasm]

TP53 N200Ifs*47 [nucleoplasm]

TP53 G108Afs*39 [nucleoplasm]

TP53 C242Afs*5 [nucleoplasm]

TP53 A69Cfs*79 [nucleoplasm]

TP53 E286Hfs*22 [nucleoplasm]

TP53 R110Pfs*14 [nucleoplasm]

TP53 V73Wfs*50 [nucleoplasm]

TP53 F109Tfs*16 [nucleoplasm]

TP53 H115Afs*34 [nucleoplasm]

TP53 W53Mfs*4 [nucleoplasm]

TP53 Q38Kfs*6 [nucleoplasm]

TP53 L188Pfs*19 [nucleoplasm]

TP53 P152Tfs*30 [nucleoplasm]

TP53 L289Sfs*56 [nucleoplasm]

TP53 G262Vfs*83 [nucleoplasm]

TP53 P77Rfs*71 [nucleoplasm]

TP53 D148Gfs*2 [nucleoplasm]

TP53 H179Mfs*68 [nucleoplasm]

TP53 G279Kfs*59 [nucleoplasm]

TP53 G279Sfs*68 [nucleoplasm]

TP53 H214Tfs*2 [nucleoplasm]

TP53 A83Gfs*65 [nucleoplasm]

TP53 T125Hfs*24 [nucleoplasm]

TP53 L206Ffs*3 [nucleoplasm]

TP53 K164Sfs*6 [nucleoplasm]

TP53 C238Vfs*9 [nucleoplasm]

TP53 L201Ifs*47 [nucleoplasm]

TP53 D207Gfs*2 [nucleoplasm]

TP53 N200Kfs*9 [nucleoplasm]

TP53 P47Rfs*76 [nucleoplasm]

TP53 M169Ifs*12 [nucleoplasm]

TP53 G334W [nucleoplasm]

TP53 G199Ffs*8 [nucleoplasm]

TP53 S106Tfs*17 [nucleoplasm]

TP53 A76Hfs*47 [nucleoplasm]

TP53 G334E [nucleoplasm]

TP53 R175Afs*72 [nucleoplasm]

TP53 N210Kfs*37 [nucleoplasm]

TP53 Q52Lfs*73 [nucleoplasm]

TP53 A276Tfs*64 [nucleoplasm]

TP53 L330F [nucleoplasm]

TP53 P278Sfs*28 [nucleoplasm]

TP53 R249Tfs*14 [nucleoplasm]

TP53 T304Lfs*41 [nucleoplasm]

TP53 A78Qfs*45 [nucleoplasm]

TP53 R337G [nucleoplasm]

TP53 R174Pfs*70 [nucleoplasm]

TP53 A74Gfs*50 [nucleoplasm]

TP53 A138Rfs*31 [nucleoplasm]

TP53 S94Cfs*30 [nucleoplasm]

TP53 P67Qfs*56 [nucleoplasm]

TP53 P301Qfs*44 [nucleoplasm]

TP53 L130Sfs*40 [nucleoplasm]

TP53 V225Ffs*23 [nucleoplasm]

TP53 P71Gfs*75 [nucleoplasm]

TP53 L308Afs*28 [nucleoplasm]

TP53 E221Gfs*25 [nucleoplasm]

TP53 R337S [nucleoplasm]

TP53 S149Pfs*21 [nucleoplasm]

TP53 P85Lfs*59 [nucleoplasm]

TP53 L43Afs*7 [nucleoplasm]

TP53 D48Tfs*75 [nucleoplasm]

TP53 R196Cfs*46 [nucleoplasm]

TP53 A88Vfs*55 [nucleoplasm]

TP53 E51Pfs*59 [nucleoplasm]

TP53 A86Pfs*34 [nucleoplasm]

TP53 L257Rfs*6 [nucleoplasm]

TP53 D57Kfs*67 [nucleoplasm]

TP53 C176Sfs*67 [nucleoplasm]

TP53 T125Sfs*45 [nucleoplasm]

TP53 Q167Sfs*3 [nucleoplasm]

TP53 Q104Rfs*19 [nucleoplasm]

TP53 R156Pfs*25 [nucleoplasm]

TP53 T284Hfs*22 [nucleoplasm]

TP53 Q104Afs*18 [nucleoplasm]

TP53 E204Tfs*39 [nucleoplasm]

TP53 P191Lfs*56 [nucleoplasm]

TP53 H115Lfs*8 [nucleoplasm]

TP53 E171Gfs*4 [nucleoplasm]

TP53 N239Pfs*6 [nucleoplasm]

TP53 G117Dfs*26 [nucleoplasm]

TP53 P316Afs*19 [nucleoplasm]

TP53 N29Kfs*13 [nucleoplasm]

TP53 S303Afs*42 [nucleoplasm]

TP53 A63Tfs*66 [nucleoplasm]

TP53 V274Cfs*32 [nucleoplasm]

TP53 L330I [nucleoplasm]

TP53 S116Afs*34 [nucleoplasm]

TP53 S185Rfs*23 [nucleoplasm]

TP53 R282Pfs*24 [nucleoplasm]

TP53 M237Vfs*2 [nucleoplasm]

TP53 L299Cfs*46 [nucleoplasm]

TP53 E298Gfs*43 [nucleoplasm]

TP53 L257Vfs*84 [nucleoplasm]

TP53 E198Afs*7 [nucleoplasm]

TP53 P36Wfs*4 [nucleoplasm]

TP53 H178Pfs*69 [nucleoplasm]

TP53 I251Sfs*94 [nucleoplasm]

TP53 C135Ffs*36 [nucleoplasm]

TP53 R283Pfs*24 [nucleoplasm]

TP53 H115Cfs*27 [nucleoplasm]

TP53 S96Ffs*53 [nucleoplasm]

TP53 Y220Rfs*25 [nucleoplasm]

TP53 S33Pfs*11 [nucleoplasm]

TP53 E198Kfs*49 [nucleoplasm]

p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]

p-S15,S20-TP53 [nucleoplasm]

p-S15-TP53 [nucleoplasm]

TP53 [nucleoplasm]

PolyUb-TP53 [cytosol]

PolyUb-TP53 [nucleoplasm]

p-S392-TP53 [nucleoplasm]

p-S37-TP53 [nucleoplasm]

PolyUb,p-S15,S20-TP53 [nucleoplasm]

p-S15,S20,S269,T284-TP53 [nucleoplasm]

p-T55-TP53 [nucleoplasm]

p-S315-TP53 [nucleoplasm]

p-S15,S20,S46-TP53 [nucleoplasm]

p-S15,S33,S46-TP53 [nucleoplasm]

p-S15,S20,S392-TP53 [nucleoplasm]

p-S15,S392-TP53 [nucleoplasm]

Ac-K382,p-S15,S20-TP53 [nucleoplasm]

Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]

Ac-K120,p-S15,S20-TP53 [nucleoplasm]

Me2K-370,382-TP53 [nucleoplasm]

MeK-370,p-S15,S20-TP53 [nucleoplasm]

Me2-K373-TP53 [nucleoplasm]

Me-K382,p-S15,S20-TP53 [nucleoplasm]

Me1-K372,p-S15,S20-TP53 [nucleoplasm]

Modified Residues

Name

L-arginine 337 replaced with L-cysteine

Coordinate

337

PsiMod

L-arginine removal [MOD:01632]

A protein modification that effectively removes or replaces an L-arginine.

L-cysteine residue [MOD:00014]

A protein modification that effectively converts a source amino acid residue to an L-cysteine.

Disease

Name	Identifier	Synonyms
Li-Fraumeni syndrome	DOID:3012	sarcoma, breast, leukaemia and adrenal gland syndrome, SBLA syndrome, Li-Fraumeni Familiar cancer Susceptibility syndrome
cancer	DOID:162	malignant tumor, malignant neoplasm, primary cancer

Cross References

RefSeq

NP_001119590.1, NP_001263627.1, NP_001263626.1, NP_001263628.1, NP_001263625.1, NP_001263624.1, NP_001263689.1, NP_000537.3, NP_001394200.1, NP_001394191.1, NP_001263690.1, NP_001394198.1, NP_001119584.1, NP_001394195.1, NP_001394193.1, NP_001394196.1, NP_001394194.1, NP_001394192.1, NP_001119585.1, NP_001119587.1, NP_001394197.1, NP_001119589.1, NP_001394199.1, NP_001119588.1, NP_001119586.1

OpenTargets

ENSG00000141510

ENSEMBL

ENST00000504290, ENSP00000519626, ENSP00000269305, ENSP00000391127, ENSP00000519624, ENSP00000426252, ENSP00000425104, ENST00000714357, ENSP00000478499, ENST00000504937, ENSP00000482537, ENST00000714359, ENST00000508793, ENST00000622645, ENST00000269305, ENST00000510385, ENST00000420246, ENSP00000481638, ENSP00000391478, ENSP00000424104, ENST00000445888, ENSP00000398846, ENSP00000484409, ENST00000620739, ENST00000610538, ENSP00000481179, ENSP00000480868, ENSP00000482222, ENST00000619485, ENST00000455263, ENST00000503591, ENST00000509690, ENST00000610292, ENSP00000478219, ENSG00000141510

Mondo

0018875

ZINC - Substances

P53_HUMAN

ZINC target

P04637

PRO

P04637

GlyGen

P04637

PDB

2AC0, 4AGQ, 1MA3, 6RWU, 7B46, 6SI0, 3KMD, 5O1B, 5MOC, 5MCU, 3Q01, 4AGM, 6GGC, 2H4F, 8R1F, 7B49, 2VUK, 1SAK, 3DAC, 7YGI, 1SAF, 2BIM, 3KZ8, 9C5S, 2X0U, 3Q06, 1XQH, 9CHT, 6RKM, 2MWP, 3IGL, 2H2F, 6FF9, 5O1E, 6VRM, 4IBZ, 2ADY, 8HLN, 3D06, 6S3C, 6RWH, 6SI1, 2GS0, 4HFZ, 3IGK, 7B4G, 1A1U, 8R1G, 6VR1, 5AB9, 4AGL, 1C26, 8E7B, 2J0Z, 5G4N, 3DAB, 2F1X, 2YBG, 6GGA, 2BIN, 6RM5, 2RUK, 8QWL, 6RKK, 8QWO, 9BR4, 3Q05, 1PES, 4LOF, 8CG7, 3OQ5, 8A32, 2PCX, 8RCI, 5HOU, 7B4H, 7B47, 2WGX, 5BUA, 6XRE, 2FEJ, 3D09, 3PDH, 7B4D, 1SAL, 6SIP, 7NMI, 4AGP, 3SAK, 5G4O, 8A92, 5AOM, 4MZR, 2BIO, 8DC4, 5MF7, 4BUZ, 7EAX, 4IBY, 5LAP, 2J1X, 5A7B, 6W51, 2J10, 1PET, 9BR3, 2J11, 3D0A, 5O1F, 2L14, 5MCV, 6RWI, 7DHZ, 2B3G, 1KZY, 2H4H, 8RBA, 3D08, 7B4N, 3D05, 2XWR, 7B4A, 6SI4, 4KVP, 1TSR, 7V97, 2BIP, 5O1I, 2FOJ, 2Z5T, 4IJT, 4LOE, 1TUP, 6RKI, 6VR5, 8J8N, 8QWN, 1YC5, 2OCJ, 2MEJ, 9FZB, 4IBT, 6RK8, 1OLG, 4X34, 7B4E, 1UOL, 2J20, 7BWN, 2FOO, 6RX2, 8HLM, 5G4M, 2BIQ, 6RZ3, 3D07, 2H4J, 7EDS, 2J1Y, 6RL6, 2LY4, 7RM4, 6SIQ, 6RWS, 8OXM, 1GZH, 1DT7, 3LW1, 5OL0, 2MZD, 3ZME, 4IBS, 2H2D, 4IBW, 5MHC, 5O1C, 7EEU, 5MG7, 5ECG, 8XP5, 2MWY, 5MCT, 7DHY, 2J21, 7XZX, 1HS5, 5O1G, 8WD2, 7B48, 8HLL, 6S40, 6SIN, 6GGD, 6V4H, 1YCQ, 4AGO, 7XZZ, 8RBC, 1YCS, 6RL4, 8OXO, 4QO1, 8DC6, 4BV2, 4IBQ, 6SLV, 8DC8, 8QWP, 6RJZ, 5O1D, 5AOK, 2AHI, 3TG5, 6SL6, 7B4F, 8E7A, 6SHZ, 6SI2, 1AIE, 2K8F, 4XR8, 4IBV, 5XZC, 8DC7, 5O1H, 6R5L, 6SIO, 6GGE, 2H59, 5ABA, 2ATA, 8UQR, 7EL4, 6S39, 8RBB, 7B4B, 1OLH, 6ZNC, 5AOI, 1SAE, 6V4F, 4ZZJ, 7DVD, 2H1L, 8QWK, 4RP7, 2X0W, 5UN8, 2Z5S, 5AOL, 8GCR, 6SI3, 7B4C, 3TS8, 1H26, 4IBU, 5MCW, 2YDR, 5O1A, 4LO9, 5HP0, 6RL3, 5HPD, 6VQO, 6RM7, 1YCR, 6GGB, 6S9Q, 4AGN, 4HJE, 2J1Z, 6FJ5, 6T58, 1JSP, 5AOJ, 6LHD, 5LGY, 6GGF, 4RP6, 2X0V, 2MWO, 8QWM, 2J1W, 8A31, 6VRN, 4MZI

COSMIC

COSV52669243

GeneCards

TP53

HPA

ENSG00000141510-TP53

Pharos - Targets

P04637

Orphanet

TP53

ZINC - Predictions - Purchasable

P53_HUMAN

Interactors (249)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00987 MDM2	11	p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) MDM2 [cytosol] (R-HSA-198644) MDM2 [nucleoplasm] (R-HSA-69486) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) MDM2 [endocytic vesicle membrane] (R-HSA-416849) MDM2 [plasma membrane] (R-HSA-416843) monoSUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472)	0.995	122
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.981	34
UniProt:Q09472 EP300	5	EP300 [nucleoplasm] (R-HSA-381325) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) monoSUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306)	0.976	22
IntAct:EBI-4399559 UBIQ			0.973	21
UniProt:O15151 MDM4	5	MDM4 [nucleoplasm] (R-HSA-349430) PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] (R-HSA-6804938) p-S346,S367,S403-MDM4 [nucleoplasm] (R-HSA-349441) p-S403-MDM4 [nucleoplasm] (R-HSA-349461) PolyUb-MDM4 [nucleoplasm] (R-HSA-6782502)	0.972	27
UniProt:P03070 LT			0.97	25
UniProt:Q93009 USP7	2	USP7 [nucleoplasm] (R-HSA-3215278) USP7 [cytosol] (R-HSA-8853511)	0.969	23
UniProt:Q92793 CREBBP	4	CREBBP [nucleoplasm] (R-HSA-193545) CREBBP [cytosol] (R-HSA-9756493) FOXO4-S-S-CREBBP [nucleoplasm] (R-HSA-9617684) monoSUMO1-K998,K1033,K1056-CREBBP [nucleoplasm] (R-HSA-3927877)	0.96	17
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-386-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783067) Ub-6-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783122)	0.96	15
UniProt:Q96EB6 SIRT1	1	SIRT1 [nucleoplasm] (R-HSA-427531)	0.957	18
IntAct:EBI-1550784 CDKN1A			0.929	22
UniProt:Q14999 CUL7	1	CUL7 [cytosol] (R-HSA-535534)	0.926	19
UniProt:Q8IWT3 CUL9	2	G76-NEDD8-K1881-CUL9 [cytosol] (R-HSA-8955921) CUL9 [cytosol] (R-HSA-8855018)	0.925	16
UniProt:Q8WTS6 SETD7	1	SETD7 [nucleoplasm] (R-HSA-1183221)	0.922	11
UniProt:Q13625 TP53BP2	1	TP53BP2 [nucleoplasm] (R-HSA-6799780)	0.903	9
UniProt:Q96PM5 RCHY1	2	RCHY1 [cytosol] (R-HSA-976013) RCHY1 [nucleoplasm] (R-HSA-5655134)	0.892	13
UniProt:Q07817-1 BCL2L1			0.881	26
UniProt:Q12888-1 TP53BP1			0.879	17
UniProt:Q9UER7 DAXX	13	DAXX [nucleoplasm] (R-HSA-3222068) DAXX A36Qfs108 [nucleoplasm] (R-HSA-9673105) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX S138 [nucleoplasm] (R-HSA-9673081) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086)	0.877	13
UniProt:Q12888 TP53BP1	3	TP53BP1 [nucleoplasm] (R-HSA-61175) p-S25,S1778-TP53BP1 [nucleoplasm] (R-HSA-5683418) monoSUMO1-K-TP53BP1 [nucleoplasm] (R-HSA-2997591)	0.87	8
UniProt:P26447 S10A4			0.848	9
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.846	14
UniProt:P45481 Crebbp	4	CREBBP [nucleoplasm] (R-MMU-193545) Crebbp [nucleoplasm] (R-MMU-556795) Foxo4-S-S-Crebbp [nucleoplasm] (R-MMU-9617719) monoSumo1-K999,K1034,K1057-Crebbp [nucleoplasm] (R-MMU-3927936)	0.845	10
UniProt:P06463 VE6			0.84	5
UniProt:P38936 CDKN1A	5	CDKN1A [nucleoplasm] (R-HSA-182585) CDKN1A [cytosol] (R-HSA-182512) p-Y77-CDKN1A [cytosol] (R-HSA-8942601) p-S130-CDKN1A [nucleoplasm] (R-HSA-187857) p-T145-CDKN1A [cytosol] (R-HSA-198614)	0.821	6
UniProt:Q15672 TWIST1	1	TWIST1 [nucleoplasm] (R-HSA-445442)	0.817	10
UniProt:Q8WUF5 PPP1R13L	1	PPP1R13L [nucleoplasm] (R-HSA-6799738)	0.815	12
UniProt:P38646 HSPA9	6	HSPA9 [mitochondrial matrix] (R-HSA-8878802) HSPA9 [mitochondrial inner membrane] (R-HSA-1252206) HSPA9(1-679) [cytosol] (R-HSA-1267964) HSPA9(1-679) [mitochondrial intermembrane space] (R-HSA-1267968) HSPA9 [nucleoplasm] (R-HSA-5252128) HSPA9 [cytosol] (R-HSA-5251993)	0.811	6
UniProt:P03126 VE6			0.807	5
UniProt:Q9NRG4 SMYD2	1	SMYD2 [nucleoplasm] (R-HSA-3222233)	0.806	6
UniProt:Q8N3Y1 FBXW8	1	FBXW8 [cytosol] (R-HSA-976017)	0.788	8
UniProt:O14641 DVL2	5	pp-DVL2 [cytosol] (R-HSA-3772398) p-DVL2 [cytosol] (R-HSA-201706) DVL2 [cytosol] (R-HSA-201694) p-DVL2 [clathrin-coated endocytic vesicle] (R-HSA-5138444) ub-DVL2 [cytosol] (R-HSA-4652689)	0.778	6
UniProt:Q05086 UBE3A	1	UBE3A [cytosol] (R-HSA-976028)	0.77	6
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.767	8
UniProt:Q923E4 Sirt1	2	Sirt1 [nucleoplasm] (R-MMU-5211238) SIRT1 [nucleoplasm] (R-MMU-427531)	0.766	4
UniProt:Q99986 VRK1	2	VRK1 [cytosol] (R-HSA-2995381) VRK1 [nucleoplasm] (R-HSA-2528998)	0.761	11
UniProt:Q05397 PTK2	11	p-6Y-PTK2 [cytosol] (R-HSA-354128) p-Y397-PTK2 [cytosol] (R-HSA-354068) PTK2 [cytosol] (R-HSA-201621) PTK2(1-772) [cytosol] (R-HSA-202827) PTK2(773-1052) [cytosol] (R-HSA-202829) p-6Y,S732-PTK2 [cytosol] (R-HSA-5218694) p-5Y,S732-PTK2 [cytosol] (R-HSA-5229006) p-5Y-PTK2 [cytosol] (R-HSA-5218711) pY-PTK2 [cytosol] (R-HSA-9632393) p-Y194,Y397-PTK2 [cytosol] (R-HSA-8874600) p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-HSA-8874613)	0.751	13
UniProt:P09874 PARP1	4	PARP1 [nucleoplasm] (R-HSA-201568) PAR-PARP1 [nucleoplasm] (R-HSA-5651713) monoSUMO1-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551686) polySUMO2,3-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551617)	0.75	5
UniProt:P09429 HMGB1	5	HC23,45-HMGB1 [extracellular region] (R-HSA-6797422) HMGB1 [nucleoplasm] (R-HSA-266221) HMGB1 [extracellular region] (R-HSA-879382) HMGB1 [ficolin-1-rich granule lumen] (R-HSA-6803291) HMGB1 [secretory granule lumen] (R-HSA-6803337)	0.74	9
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.738	5
UniProt:P53350 PLK1	4	PLK1 [cytosol] (R-HSA-164603) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) p-T210-PLK1 [cytosol] (R-HSA-3000318) PLK1 [nucleoplasm] (R-HSA-156720)	0.737	6
UniProt:P63279 UBE2I	9	monoSUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) UBE2I [cytosol] (R-HSA-4655342) SUMO2-C93-UBE2I [cytosol] (R-HSA-4656944)	0.737	5
UniProt:Q9NPI1 BRD7	1	BRD7 [nucleoplasm] (R-HSA-3222092)	0.729	9
UniProt:P43356 MAGA2			0.729	7
UniProt:O14503 BHLHE40	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.728	11
UniProt:P19784 CSNK2A2	2	CSNK2A2 [cytosol] (R-HSA-201721) CSNK2A2 [nucleoplasm] (R-HSA-6805065)	0.725	4
UniProt:Q99615 DNAJC7	2	DNAJC7 [nucleoplasm] (R-HSA-5255408) DNAJC7 [cytosol] (R-HSA-5252099)	0.725	5
UniProt:Q9UBL3 ASH2L	1	ASH2L [nucleoplasm] (R-HSA-1629834)	0.723	8
UniProt:P63165 SUMO1	11	lysyl-G97-SUMO1 [nucleoplasm] (R-HSA-9761562) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831) SUMO1 [nucleoplasm] (R-HSA-877304) UBA2-G97-SUMO1 [nucleoplasm] (R-HSA-3730616) UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-3730622) lysyl-G97-SUMO1 [cytosol] (R-HSA-9762266) lysyl-G97-SUMO1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-9762380) UBE2I-G97-SUMO1 [cytosol] (R-HSA-4656941) lysyl-G97-SUMO1 [viral capsid] (R-HSA-9762386) lysyl-G97-SUMO1 [nucleolus] (R-HSA-9762385) lysyl-G97-SUMO1 [plasma membrane] (R-HSA-9762382)	0.722	3
UniProt:P32776	1	TFB1 [nucleoplasm] (R-SCE-65912)	0.719	7
UniProt:P32780 GTF2H1	1	GTF2H1 [nucleoplasm] (R-HSA-65912)	0.719	12
UniProt:Q8NHY2 COP1	3	p-S387-RFWD2 [nucleoplasm] (R-HSA-349450) RFWD2 [nucleoplasm] (R-HSA-349454) p-S387-RFWD2 [cytosol] (R-HSA-349439)	0.717	5
UniProt:Q96KB5 TOPK			0.715	7
UniProt:P13693 TCTP			0.715	7
UniProt:Q16666-2 IFI16			0.715	6
UniProt:Q9H2X6 HIPK2	3	p-HIPK2 [nucleoplasm] (R-HSA-6799375) HIPK2 [nucleoplasm] (R-HSA-3215222) monoSUMO1-K32-HIPK2 [nucleoplasm] (R-HSA-4090405)	0.713	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.709	19
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.706	18
UniProt:P29590 PML	5	PML [cytosol] (R-HSA-5624327) PML [nucleoplasm] (R-HSA-1031706) monoSUMO1-K65,160,490-PML [nucleoplasm] (R-HSA-3000440) polySUMO2-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000423) polySUMO3-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000386)	0.7	4
UniProt:Q9BUJ2 HNRNPUL1	1	HNRNPUL1 [nucleoplasm] (R-HSA-72106)	0.697	12
UniProt:O14920 IKBKB	3	IKBKB [cytosol] (R-HSA-168114) p-S177,S181-IKBKB [cytosol] (R-HSA-202506) IKBKB Q432Pfs*62 [cytosol] (R-HSA-9628518)	0.692	3
UniProt:O95376 ARIH2	1	ARIH2 [cytosol] (R-HSA-975987)	0.691	5
UniProt:Q15291 RBBP5	1	RBBP5 [nucleoplasm] (R-HSA-1629836)	0.69	5
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.69	5
UniProt:P02829	11	HSP90AA1 [cytosol] (R-SCE-192864) HSP90AB1 [nucleoplasm] (R-SCE-5082399) HSP90AA1 [nucleoplasm] (R-SCE-5082401) HSP90AB1 [cytosol] (R-SCE-419617) HSP90AA1 [plasma membrane] (R-SCE-534996) HSP90AB1 [ficolin-1-rich granule lumen] (R-SCE-6801491) HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470) HSP90AA1 [extracellular region] (R-SCE-3221946) HSP90AB1 [extracellular region] (R-SCE-6806463) HSP90AA1 [secretory granule lumen] (R-SCE-6801515) HSP90AB1 [secretory granule lumen] (R-SCE-6801477)	0.678	8
UniProt:Q9NRR4 DROSHA	1	DROSHA [nucleoplasm] (R-HSA-1482510)	0.677	5
UniProt:P06703 S10A6			0.676	3
UniProt:P29034 S10A2			0.676	4
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.676	6
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.675	3
UniProt:Q15796 SMAD2	20	Ub-SMAD2 [cytosol] (R-HSA-6782774) p-S465,S467-SMAD2 P305L [cytosol] (R-HSA-3315471) p-S465,S467-SMAD2 D300A [cytosol] (R-HSA-3315064) p-S465,S467-SMAD2 D300N [cytosol] (R-HSA-3315066) p-S465,S467-SMAD2 A354T [cytosol] (R-HSA-3315474) p-S465,S467-SMAD2 P305Q [cytosol] (R-HSA-3315070) p-S465,S467-SMAD2 [nucleoplasm] (R-HSA-3009185) p-S465,S467-SMAD2 [cytosol] (R-HSA-3009186) SMAD2 [cytosol] (R-HSA-3006353) p-T220,S465,S467-SMAD2 [nucleoplasm] (R-HSA-3009189) Ub,p-T220,S465,S467-SMAD2 [nucleoplasm] (R-HSA-9773843) SMAD2 [nucleoplasm] (R-HSA-3006352) p-S250-SMAD2 [cytosol] (R-HSA-9731121) SMAD2 Q429* [cytosol] (R-HSA-9668727) SMAD2 S467P [cytosol] (R-HSA-3304375) SMAD2 L315* [cytosol] (R-HSA-9668725) SMAD2 E439* [cytosol] (R-HSA-9668724) SMAD2 Q455* [cytosol] (R-HSA-9668731) SMAD2 S306* [cytosol] (R-HSA-9668730) SMAD2 S296* [cytosol] (R-HSA-9668729)	0.674	7
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.669	3
UniProt:Q96M61 MAGBI			0.668	3
UniProt:P31948 STIP1	1	STIP1 [cytosol] (R-HSA-443857)	0.666	4
UniProt:P04792 HSPB1	3	HSPB1 [cytosol] (R-HSA-450563) p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.665	3
UniProt:O60341-1 KDM1A			0.664	6
UniProt:P26663-PRO_0000037536			0.664	9
UniProt:P48643 CCT5	1	CCT5 [cytosol] (R-HSA-390447)	0.659	3
UniProt:P03120 VE2			0.658	3
UniProt:P49841 GSK3B	5	GSK3B [nucleoplasm] (R-HSA-2022823) GSK3B [cytosol] (R-HSA-2997551) p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B [endoplasmic reticulum lumen] (R-HSA-9931408) GSK3B del304-316 [cytosol] (R-HSA-5339682)	0.658	3
UniProt:P17844 DDX5	4	DDX5 [nucleoplasm] (R-HSA-3900136) DDX5 [cytosol] (R-HSA-9682643) polySUMO2-K53-DDX5 [nucleoplasm] (R-HSA-3900186) monoSUMO1-K53-DDX5 [nucleoplasm] (R-HSA-3900041)	0.656	6
UniProt:P51587 BRCA2	20	BRCA2 D2983Ffs34 [cytosol] (R-HSA-9709538) BRCA2 K2555 [cytosol] (R-HSA-9711337) BRCA2 N2553Tfs95 [cytosol] (R-HSA-9712872) BRCA2 T2685Hfs9 [cytosol] (R-HSA-9712879) BRCA2 K2674Rfs2 [cytosol] (R-HSA-9712610) BRCA2 S3231 [cytosol] (R-HSA-9711458) BRCA2 I2675Dfs6 [cytosol] (R-HSA-9712869) BRCA2 R2625 [cytosol] (R-HSA-9711482) BRCA2 E3071* [cytosol] (R-HSA-9711354) BRCA2 V2716Wfs17 [cytosol] (R-HSA-9712761) BRCA2 W2586 [cytosol] (R-HSA-9711487) BRCA2 P2767Lfs10 [cytosol] (R-HSA-9712509) BRCA2 K3032 [cytosol] (R-HSA-9711485) BRCA2 S2835* [cytosol] (R-HSA-9711345) BRCA2 Y3006* [cytosol] (R-HSA-9711222) BRCA2 L2926* [cytosol] (R-HSA-9711348) BRCA2 R3128* [cytosol] (R-HSA-9711177) BRCA2 E2599* [cytosol] (R-HSA-9711304) BRCA2 E2571* [cytosol] (R-HSA-9711560) BRCA2 Y2977* [cytosol] (R-HSA-9711182)	0.655	7
UniProt:Q13362 PPP2R5C	3	PPP2R5C [cytosol] (R-HSA-3008954) p-S337-PPP2R5C [cytosol] (R-HSA-6811447) PPP2R5C [nucleoplasm] (R-HSA-3008946)	0.65	4
UniProt:Q06587 RING1	1	RING1 [nucleoplasm] (R-HSA-389113)	0.65	7
UniProt:Q14191 WRN	2	WRN [nucleoplasm] (R-HSA-67387) monoSUMO1-K356,K496,K898-WRN [nucleoplasm] (R-HSA-4568904)	0.647	5
UniProt:O96017 CHEK2	3	p-S,3T-CHEK2 [nucleoplasm] (R-HSA-5683784) CHEK2 [nucleoplasm] (R-HSA-113824) p-T68-CHEK2 [nucleoplasm] (R-HSA-113825)	0.646	3
UniProt:Q9BV47 DUS26			0.645	9
UniProt:Q86XK2 FBXO11	1	FBXO11 [cytosol] (R-HSA-8955092)	0.645	4
UniProt:Q06330 RBPJ	1	RBPJ [nucleoplasm] (R-HSA-3008668)	0.645	5
UniProt:Q9Y618 NCOR2	2	NCOR2 [nucleoplasm] (R-HSA-442469) monoSUMO1-K672-NCOR2 [nucleoplasm] (R-HSA-3927904)	0.645	7
UniProt:Q92569 PIK3R3	2	PIK3R3 [cytosol] (R-HSA-205223) K63polyUb-PIK3R3 [cytosol] (R-HSA-3080574)	0.644	5
UniProt:Q9UPR3 SMG5	1	SMG5 [cytosol] (R-HSA-927867)	0.643	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.643	5
IntAct:EBI-1550787 MDM2			0.643	3
UniProt:O95816 BAG2	1	BAG2 [cytosol] (R-HSA-5255445)	0.643	4
UniProt:P30405 PPIF			0.639	4
UniProt:Q6NYC1 JMJD6	1	JMJD6 [nucleoplasm] (R-HSA-4754226)	0.639	7
UniProt:Q96FW1 OTUB1	2	OTUB1 [cytosol] (R-HSA-933411) OTUB1 [nucleoplasm] (R-HSA-6783242)	0.632	8
UniProt:P49757 NUMB	1	NUMB [plasma membrane] (R-HSA-443595)	0.632	5
UniProt:Q9Y3T9 NOC2L	1	NOC2L [nucleoplasm] (R-HSA-3222129)	0.632	8
UniProt:P30153 PPP2R1A	2	PPP2R1A [cytosol] (R-HSA-165982) PPP2R1A [nucleoplasm] (R-HSA-165968)	0.628	3
UniProt:P04019 VE6			0.623	2
UniProt:Q8N488 RYBP	1	RYBP [nucleoplasm] (R-HSA-8937975)	0.623	4
UniProt:Q8N726 CDKN2A	12	p14ARF [nucleoplasm] (R-HSA-1629813) p14ARF [cytosol] (R-HSA-9645669) p14ARF [mitochondrial matrix] (R-HSA-9645695) p14ARF R98L;R99S [cytosol] (R-HSA-9645730) p14ARF R82C [cytosol] (R-HSA-9645750) p14ARF R90H [cytosol] (R-HSA-9645755) p14ARF R88Q [cytosol] (R-HSA-9645754) p14ARF R87C [cytosol] (R-HSA-9645759) p14ARF R81G [cytosol] (R-HSA-9645741) p14ARF R98Q [cytosol] (R-HSA-9645757) p14ARF R99C [cytosol] (R-HSA-9645756) p14ARF V22Pfs*46 [cytosol] (R-HSA-9646285)	0.623	3
UniProt:P23297 S100A1	1	S100A1 [extracellular region] (R-HSA-6805991)	0.623	3
UniProt:Q6PCD5 RFWD3			0.623	5
UniProt:P04271 S100B	1	S100B [extracellular region] (R-HSA-879433)	0.623	3
UniProt:P35232 PHB1	2	PHB [cytosol] (R-HSA-5672944) PHB [mitochondrial inner membrane] (R-HSA-8953720)	0.619	6
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.619	10
UniProt:Q15831 STK11	2	STK11 [cytosol] (R-HSA-380954) STK11 [nucleoplasm] (R-HSA-164119)	0.615	3
UniProt:P46777 RPL5	1	RPL5 [cytosol] (R-HSA-72482)	0.615	3
UniProt:Q86TM6 SYVN1	1	SYVN1(1-617) [endoplasmic reticulum membrane] (R-HSA-535496)	0.61	5
UniProt:Q9BWC9 CC106			0.608	3
UniProt:O43741 PRKAB2	3	PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [nucleoplasm] (R-HSA-164096) PRKAB2 [endoplasmic reticulum lumen] (R-HSA-9931271)	0.607	3
UniProt:P41235 HNF4A	1	HNF4A [nucleoplasm] (R-HSA-446162)	0.604	3
UniProt:P15036 ETS2	2	p-T72-ETS2 [nucleoplasm] (R-HSA-3132735) ETS2 [nucleoplasm] (R-HSA-1629811)	0.602	4
UniProt:P89055 P89055			0.602	6
UniProt:Q05655 PRKCD	12	PRKCD [cytosol] (R-HSA-58200) PRKCD(1-329) [cytosol] (R-HSA-212547) PRKCD(330-676) [cytosol] (R-HSA-212551) p-T507,S645,S664-PRKCD(1-676) [plasma membrane] (R-HSA-198294) active p-T507,S645,S664-PRKCD [plasma membrane] (R-HSA-5607635) p-T507,S645,S664-PRKCD [cytosol] (R-HSA-5218734) p-T507-PRKCD [cytosol] (R-HSA-5218746) PRKCD(330-676) [azurophil granule lumen] (R-HSA-6799221) PRKCD(1-329) [azurophil granule lumen] (R-HSA-6799219) PRKCD(1-329) [extracellular region] (R-HSA-6806226) PRKCD(330-676) [extracellular region] (R-HSA-6806199) PRKCD(1-676) [nucleoplasm] (R-HSA-450606)	0.602	4
UniProt:Q9UHH9 IP6K2	1	IP6K2 [nucleoplasm] (R-HSA-1015687)	0.602	4
UniProt:Q9UHC7 MKRN1	2	MKRN1 [cytosol] (R-HSA-976042) p-S109-MKRN1 [cytosol] (R-HSA-8948758)	0.602	8
UniProt:Q9P0U4 CXXC1	1	CXXC1 [nucleoplasm] (R-HSA-535610)	0.597	7
UniProt:Q13155 AIMP2	1	AIMP2 [cytosol] (R-HSA-379576)	0.593	6
UniProt:Q96SB4 SRPK1	2	SRPK1 [cytosol] (R-HSA-9729349) SRPK1 [nucleoplasm] (R-HSA-9821984)	0.591	3
UniProt:Q06945 SOX4	1	SOX4 [nucleoplasm] (R-HSA-5625832)	0.591	4
UniProt:Q9UBF1 MAGC2			0.591	3
UniProt:O60285 NUAK1	2	p-T211-NUAK1 [nucleoplasm] (R-HSA-3222011) NUAK1 [nucleoplasm] (R-HSA-3222004)	0.591	5
UniProt:Q8TAQ5 ZNF420	2	ZNF420 [nucleoplasm] (R-HSA-1247509) p-S68-ZNF420 [nucleoplasm] (R-HSA-6799095)	0.591	4
UniProt:P23396 RPS3	2	RPS3 [cytosol] (R-HSA-72369) RPS3 [nucleoplasm] (R-HSA-6798714)	0.59	4
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) polySUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.589	2
UniProt:Q96ST3 SIN3A	2	SIN3A [nucleoplasm] (R-HSA-351657) monoSUMO1-SIN3A [nucleoplasm] (R-HSA-4086071)	0.589	2
UniProt:Q9H3D4 TP63	1	TP63 [nucleoplasm] (R-HSA-2997585)	0.589	5
UniProt:O14980 XPO1	2	XPO1 [cytosol] (R-HSA-165539) XPO1 [nucleoplasm] (R-HSA-165529)	0.589	3
UniProt:P08047 SP1	1	SP1 [nucleoplasm] (R-HSA-1592223)	0.589	6
UniProt:P22736 NR4A1	2	NR4A1 [nucleoplasm] (R-HSA-199831) p-S351-NR4A1 [nucleoplasm] (R-HSA-199846)	0.581	6
UniProt:Q96GM8 TOE1			0.577	3
UniProt:P61289 PSME3	1	PSME3 [cytosol] (R-HSA-68816)	0.576	7
UniProt:O43847 NRDC			0.576	6
UniProt:O75925 PIAS1	1	PIAS1 [nucleoplasm] (R-HSA-877307)	0.571	4
UniProt:O14757 CHEK1	3	p-S317,S345-CHEK1 [nucleoplasm] (R-HSA-113838) CHEK1 [nucleoplasm] (R-HSA-113826) CHEK1 [cytosol] (R-HSA-205285)	0.571	2
UniProt:Q96GD4 AURKB	3	AURKB [cytosol] (R-HSA-174231) AURKB [nucleoplasm] (R-HSA-4655360) polySUMO2,3-K202-AURKB [cytosol] (R-HSA-4655414)	0.571	2
UniProt:Q9H7Z6 KAT8	1	KAT8 [nucleoplasm] (R-HSA-3321802)	0.564	2
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.564	2
UniProt:P25208 NFYB	1	NFYB [nucleoplasm] (R-HSA-381067)	0.564	6
UniProt:P10415 BCL2	1	BCL2 [mitochondrial outer membrane] (R-HSA-50757)	0.564	5
UniProt:P06748-1 NPM1			0.564	3
UniProt:P19338 NCL	4	NCL [cytosol] (R-HSA-450514) NCL [plasma membrane] (R-HSA-9836466) NCL [macropinosome membrane] (R-HSA-9837666) NCL [nucleoplasm] (R-HSA-6791213)	0.558	2
UniProt:P00519 ABL1	6	p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) ABL1 [nucleoplasm] (R-HSA-5686579) p-Y226,Y393-ABL1 [cytosol] (R-HSA-8942610) ABL1 [cytosol] (R-HSA-375987) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) p-Y393-ABL1 [cytosol] (R-HSA-9865161)	0.558	2
UniProt:Q7Z412 PEX26	2	PEX26 [cytosol] (R-HSA-9603779) PEX26 [peroxisomal membrane] (R-HSA-9033092)	0.556	3
UniProt:P13473-2 P134732			0.556	3
IntAct:EBI-25865403 EHD27213144			0.556	3
UniProt:Q15424 SAFB	3	SAFB [nucleoplasm] (R-HSA-4085379) polySUMO2,3-K231,K294-SAFB [nucleoplasm] (R-HSA-4085357) monoSUMO1-K231,K294-SAFB [nucleoplasm] (R-HSA-4085343)	0.556	5
UniProt:P21333-2 FLNA			0.556	3
UniProt:A0A6Q8PF08 A0A6Q8PF08			0.556	3
IntAct:EBI-16429055 CCSB ISOFORM ID			0.556	3
UniProt:P17676 CEBPB	3	p-T235, S321-CEBPB [nucleoplasm] (R-HSA-3857339) p-T235-CEBPB [nucleoplasm] (R-HSA-3857343) CEBPB [nucleoplasm] (R-HSA-381378)	0.556	4
UniProt:P09936 UCHL1	1	UCHL1 [cytosol] (R-HSA-5660679)	0.556	3
UniProt:P46821 MAP1B	1	MAP1B(2-2206) [cytosol] (R-HSA-9836954)	0.556	6
UniProt:P55212 CASP6	5	CASP6(194-293) [cytosol] (R-HSA-266128) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
UniProt:Q9BQA5 HINFP			0.553	2
UniProt:P15056 BRAF	20	BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620) BRAF T244P [cytosol] (R-HSA-9651165)	0.553	4
UniProt:P04183 TK1	1	TK1 [cytosol] (R-HSA-73500)	0.553	2
UniProt:Q99608 NDN	1	NDN [nucleoplasm] (R-HSA-6789966)	0.547	4
UniProt:P38398 BRCA1	20	polySUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) monoSUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) BRCA1 M1411T [nucleoplasm] (R-HSA-9702140) BRCA1 M1400V [nucleoplasm] (R-HSA-9701202) BRCA1 L1407P [nucleoplasm] (R-HSA-9702135) BRCA1 Y777* [nucleoplasm] (R-HSA-9702765) BRCA1 S1009* [nucleoplasm] (R-HSA-9702755) BRCA1 P724Lfs12 [nucleoplasm] (R-HSA-9703778) BRCA1 S451 [nucleoplasm] (R-HSA-9702754) BRCA1 S864* [nucleoplasm] (R-HSA-9702752) BRCA1 P897Kfs5 [nucleoplasm] (R-HSA-9703782) BRCA1 N555Kfs17 [nucleoplasm] (R-HSA-9703781) BRCA1 Y1127Sfs6 [nucleoplasm] (R-HSA-9703780) BRCA1 S886Cfs16 [nucleoplasm] (R-HSA-9703802) BRCA1 V83Cfs2 [nucleoplasm] (R-HSA-9703800) BRCA1 T464Pfs11 [nucleoplasm] (R-HSA-9703807) BRCA1 G813Dfs2 [nucleoplasm] (R-HSA-9703549) BRCA1 V340Gfs6 [nucleoplasm] (R-HSA-9703804) BRCA1 Y655* [nucleoplasm] (R-HSA-9702769) BRCA1 W372* [nucleoplasm] (R-HSA-9702768)	0.544	2
UniProt:P55060 XPO2			0.544	5
UniProt:Q8R5A0	1	SMYD2 [nucleoplasm] (R-MMU-3222233)	0.544	3
UniProt:O60936 NOL3			0.544	3
UniProt:Q9PST7 Q9PST7			0.544	3
UniProt:P33763 S10A5			0.544	2
UniProt:P29066	6	ARRB1 [cytoplasmic vesicle membrane] (R-RNO-351187) ARRB1 [Golgi membrane] (R-RNO-350831) ARRB1 [lysosomal membrane] (R-RNO-432701) ARRB1 [endocytic vesicle membrane] (R-RNO-9910882) PolyUb-ARRB1 [cytosol] (R-RNO-6783186) ARRB1 [cytosol] (R-RNO-264470)	0.544	3
UniProt:P25815 S100P	2	S100P [extracellular region] (R-HSA-6804809) S100P [secretory granule lumen] (R-HSA-6804782)	0.544	2
UniProt:P31949 S100A11	2	S100A11 [extracellular region] (R-HSA-6804808) S100A11 [secretory granule lumen] (R-HSA-6804784)	0.544	2
UniProt:Q9H9J4-2 USP42			0.544	2
UniProt:P04731 MT1A	1	MT1A [cytosol] (R-HSA-5660412)	0.544	3
UniProt:P23511 NFYA	1	NFYA [nucleoplasm] (R-HSA-420841)	0.537	11
UniProt:P11473 VDR	2	VDR [nucleoplasm] (R-HSA-375512) polySUMO2-VDR [nucleoplasm] (R-HSA-4546376)	0.537	6
UniProt:Q99728 BARD1	13	K6PolyUb,p-T714,T734-BARD1 [nucleoplasm] (R-HSA-9707286) p-T714,T734-BARD1 [nucleoplasm] (R-HSA-5659846) BARD1 [nucleoplasm] (R-HSA-5659775) K6PolyUb-BARD1 [nucleoplasm] (R-HSA-9701024) BARD1 C83G [nucleoplasm] (R-HSA-9699139) BARD1 C50G [nucleoplasm] (R-HSA-9699137) BARD1 L44R [nucleoplasm] (R-HSA-9699126) BARD1 H68Y [nucleoplasm] (R-HSA-9699151) BARD1 W34R [nucleoplasm] (R-HSA-9699166) BARD1 G623W [nucleoplasm] (R-HSA-9699148) BARD1 C53W [nucleoplasm] (R-HSA-9700807) BARD1 C71Y [nucleoplasm] (R-HSA-9700808) BARD1 G623E [nucleoplasm] (R-HSA-9699135)	0.536	2
UniProt:P34931 HSPA1L	2	HSPA1L [nucleoplasm] (R-HSA-5082367) HSPA1L [cytosol] (R-HSA-3371410)	0.536	2
UniProt:Q8TDN4 CABLES1	2	CABLES1 [cytosol] (R-HSA-1013859) CABLES1 [nucleoplasm] (R-HSA-1013870)	0.536	2
UniProt:O43524 FOXO3	11	FOXO3 [nucleoplasm] (R-HSA-199305) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413) Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841849) FOXO3(?-673) [mitochondrial matrix] (R-HSA-9841824) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) FOXO3 [cytosol] (R-HSA-5687032) p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010)	0.536	2
UniProt:O15047 SETD1A	1	SETD1A [nucleoplasm] (R-HSA-3239027)	0.532	4
UniProt:P27958-PRO_0000037566			0.528	2
UniProt:Q99832 CCT7	1	CCT7 [cytosol] (R-HSA-390451)	0.527	2
UniProt:Q9NTK5 OLA1	2	OLA1 [extracellular region] (R-HSA-8863004) OLA1 [platelet alpha granule lumen] (R-HSA-8862978)	0.527	2
UniProt:P40227 CCT6A	1	CCT6A [cytosol] (R-HSA-390454)	0.527	2
UniProt:Q9H0W5 CCDC8	1	CCDC8 [cytosol] (R-HSA-8955915)	0.527	2
UniProt:Q8TBX8 PIP4K2C	2	PIP4K2C [cytosol] (R-HSA-1604638) PIP4K2C [nucleoplasm] (R-HSA-6811499)	0.527	2
UniProt:P50991 CCT4	1	CCT4 [cytosol] (R-HSA-390458)	0.527	2
UniProt:O75147 OBSL1	1	OBSL1 [cytosol] (R-HSA-8955929)	0.527	2
IntAct:EBI-1550792 TP53I3			0.527	3
UniProt:O43189 PHF1	1	PHF1 [nucleoplasm] (R-HSA-5084105)	0.527	2
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.527	2
UniProt:P78371 CCT2	3	CCT2 [cytosol] (R-HSA-390464) CCT2 [azurophil granule lumen] (R-HSA-6799356) CCT2 [extracellular region] (R-HSA-6806220)	0.527	2
UniProt:P49368 CCT3	1	CCT3 [cytosol] (R-HSA-390463)	0.527	2
UniProt:Q96PZ2 F111A			0.527	4
UniProt:Q9UL15 BAG5	1	BAG5 [cytosol] (R-HSA-5255453)	0.527	4
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.527	3
UniProt:P06400 RB1	20	RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288)	0.527	2
IntAct:EBI-6620336 CD44			0.525	2
UniProt:Q8IZD2 KMT2E			0.524	4
UniProt:O95352-2 ATG7			0.524	4
UniProt:Q7Z6Z7 HUWE1	4	HUWE1 [cytosol] (R-HSA-975983) HUWE1 [ficolin-1-rich granule lumen] (R-HSA-6801467) HUWE1 [extracellular region] (R-HSA-6806466) HUWE1 [secretory granule lumen] (R-HSA-6801481)	0.524	3
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.524	3
UniProt:Q7L7W2 Q7L7W2			0.524	2
UniProt:P61978-2 HNRNPK			0.524	2
UniProt:O95863 SNAI1	1	SNAI1 [nucleoplasm] (R-HSA-2980903)	0.524	2
UniProt:P26687 Twist1	2	Twist1 [nucleoplasm] (R-MMU-9007846) Twist1 [nucleoplasm] (R-MMU-445442)	0.524	4
UniProt:Q96PU4 UHRF2	1	UHRF2 [nucleoplasm] (R-HSA-976050)	0.524	3
UniProt:Q08619 IFI5B			0.524	2
UniProt:P36873-1 PPP1CC			0.524	2
UniProt:Q03701 CEBPZ			0.524	2
UniProt:Q12772 SREBF2	5	SREBF2(1-1141) [Golgi membrane] (R-HSA-1655747) SREBF2(1-522) [Golgi membrane] (R-HSA-1655752) SREBF2(1-484) [cytosol] (R-HSA-1655723) SREBF2(1-1141) [endoplasmic reticulum membrane] (R-HSA-1655733) SREBF2(1-484) [nucleoplasm] (R-HSA-1655745)	0.524	3
UniProt:O15169 AXIN1	11	AXIN1 [cytosol] (R-HSA-195249) p-T481,S486,S493-AXIN1 [cytosol] (R-HSA-206040) Ub-RibC-AXIN1 [cytosol] (R-HSA-3640864) RibC-AXIN1 [cytosol] (R-HSA-3640841) ub-AXIN1 [cytosol] (R-HSA-4641133) AXIN1 P255S [cytosol] (R-HSA-5251505) AXIN1 P354L [cytosol] (R-HSA-5251511) AXIN1 W247* [cytosol] (R-HSA-5251512) AXIN1 E406* [cytosol] (R-HSA-5251500) AXIN1 Y346* [cytosol] (R-HSA-4839753) AXIN1 L396M [cytosol] (R-HSA-5251503)	0.524	4
UniProt:O15164 TRIM24	4	TRIM24(1-510)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802555) TRIM24(1-510)-BRAF(381-766) fusion [cytosol] (R-HSA-6802477) TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1839012) TRIM24(1-626)-FGFR1(429-822) fusion [cytosol] (R-HSA-1614442)	0.524	3
UniProt:Q15466 NR0B2	1	NR0B2 [nucleoplasm] (R-HSA-376312)	0.524	3
UniProt:Q92841 DDX17	2	DDX17 [nucleoplasm] (R-HSA-3900090) monoSUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104)	0.524	3
UniProt:P11274 BCR	4	BCR(1-584)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838979) p-Y177-BCR(1-584)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1839041) BCR(1-584)-FGFR1(429-822) fusion [cytosol] (R-HSA-1604524) BCR [cytosol] (R-HSA-195200)	0.519	2
UniProt:O75928 PIAS2	1	PIAS2 [nucleoplasm] (R-HSA-2993787)	0.519	2
UniProt:Q16363 LAMA4	1	LAMA4 [extracellular region] (R-HSA-2328105)	0.519	2
UniProt:Q16665 HIF1A	7	HIF1A [nucleoplasm] (R-HSA-1234135) HIF1A [cytosol] (R-HSA-1234102) p-Y565-HIF1A [cytosol] (R-HSA-8857584) p-Y565,S797-HIF1A [cytosol] (R-HSA-9634700) 2xHP-HIF1A [cytosol] (R-HSA-1234131) 2xHP-HIF1A [nucleoplasm] (R-HSA-1234105) HN-HIF1A [cytosol] (R-HSA-1234110)	0.519	2
UniProt:Q8N2W9 PIAS4	2	PIAS4 [nucleoplasm] (R-HSA-2993789) monoSUMO1-K35-PIAS4 [nucleoplasm] (R-HSA-3968415)	0.508	2
UniProt:Q9BX70 BTBD2			0.508	2
UniProt:P51114 FXR1	2	FXR1(2-784)-BRAF(381-766) fusion [cytosol] (R-HSA-6802326) FXR1(2-784)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802530)	0.508	2
UniProt:Q9NZN9 AIPL1			0.508	2
UniProt:Q86Z02 HIPK1	1	HIPK1 [nucleoplasm] (R-HSA-3215224)	0.508	2
UniProt:O75970 MPDZ			0.499	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.499	3
UniProt:P49407 ARRB1	6	ARRB1 [cytosol] (R-HSA-264470) PolyUb-ARRB1 [cytosol] (R-HSA-6783186) ARRB1 [endocytic vesicle membrane] (R-HSA-9910882) ARRB1 [lysosomal membrane] (R-HSA-432701) ARRB1 [Golgi membrane] (R-HSA-350831) ARRB1 [cytoplasmic vesicle membrane] (R-HSA-351187)	0.499	5
UniProt:Q8TEW0 PARD3	3	PARD3 [cell junction] (R-HSA-2134481) PARD3 [cytosol] (R-HSA-419993) PARD3 [plasma membrane] (R-HSA-419980)	0.499	3
UniProt:Q8N9N5 BANP	2	BANP [cytosol] (R-HSA-9934681) BANP [nucleoplasm] (R-HSA-3221973)	0.499	3
UniProt:Q60953-2 PML			0.499	3
UniProt:P29590-5 PML			0.491	2
UniProt:P16885 PLCG2	8	p-PLCG2 [plasma membrane] (R-HSA-114602) PLCG2 [plasma membrane] (R-HSA-114601) p-Y753,Y759,Y1217-PLCG2 [plasma membrane] (R-HSA-984816) PLCG2 [cytosol] (R-HSA-984806) p-4Y-PLCG2 [plasma membrane] (R-HSA-2685601) p-Y753,Y759-PLCG2 [plasma membrane] (R-HSA-5607640) p-Y753,Y759-PLCG2 [cytosol] (R-HSA-5607631) p-Y-PLCG2 [cytosol] (R-HSA-9029105)	0.488	2
UniProt:P24830 VE2			0.488	2
UniProt:Q96CJ1 EAF2	1	EAF2 [nucleoplasm] (R-HSA-8932790)	0.488	2
UniProt:Q16666 IFI16	1	IFI16 [cytosol] (R-HSA-1834934)	0.488	2
UniProt:P49959 MRE11	2	MRE11A [nucleoplasm] (R-HSA-59544) MRE11A [cytosol] (R-HSA-3204309)	0.483	2
UniProt:P42336 PIK3CA	20	PIK3CA H1047L [cytosol] (R-HSA-1500714) PIK3CA H1047R [cytosol] (R-HSA-1500716) PIK3CA [cytosol] (R-HSA-74787) PIK3CA R38C [cytosol] (R-HSA-1500691) PIK3CA R38G [cytosol] (R-HSA-2395950) PIK3CA R38S [cytosol] (R-HSA-2395947) PIK3CA R38H [cytosol] (R-HSA-1500718) PIK3CA E542Q [cytosol] (R-HSA-2328003) PIK3CA Q546P [cytosol] (R-HSA-1500695) PIK3CA Q546R [cytosol] (R-HSA-2362373) PIK3CA Q546H [cytosol] (R-HSA-2362374) PIK3CA E545G [cytosol] (R-HSA-1500709) PIK3CA Q546L [cytosol] (R-HSA-2362375) PIK3CA E542V [cytosol] (R-HSA-2328074) PIK3CA E545V [cytosol] (R-HSA-2362365) PIK3CA Q546E [cytosol] (R-HSA-2362383) PIK3CA E545Q [cytosol] (R-HSA-2362362) PIK3CA E545K [cytosol] (R-HSA-1500706) PIK3CA E545A [cytosol] (R-HSA-2362355) PIK3CA Q546K [cytosol] (R-HSA-1500705)	0.483	2
UniProt:P01106 MYC	2	MYC [nucleoplasm] (R-HSA-188379) PolyUb-MYC [nucleoplasm] (R-HSA-6783169)	0.483	2
UniProt:P42345 MTOR	2	MTOR [cytosol] (R-HSA-165662) MTOR [nucleoplasm] (R-HSA-5083674)	0.483	2
UniProt:O95644 NFATC1	3	p-12S-NFATC1 [cytosol] (R-HSA-2025953) p-S257-NFATC1 [cytosol] (R-HSA-2685618) p-S257-NFATC1 [nucleoplasm] (R-HSA-2025935)	0.483	2
UniProt:O15379 HDAC3	2	HDAC3 [nucleoplasm] (R-HSA-442464) Unfolded HDAC3 [cytosol] (R-HSA-6813777)	0.483	2
UniProt:Q969H0 FBXW7	1	FBXW7 [cytosol] (R-HSA-391304)	0.483	5
UniProt:P51532 SMARCA4	1	SMARCA4 [nucleoplasm] (R-HSA-201686)	0.483	2
UniProt:O00255 MEN1	4	MEN1 [nucleoplasm] (R-HSA-2186626) MEN1 [endoplasmic reticulum lumen] (R-HSA-8956785) p-MEN1 [endoplasmic reticulum lumen] (R-HSA-8956901) MEN1 [cytosol] (R-HSA-5672315)	0.483	2
UniProt:P23769 GATA2	1	GATA2 [nucleoplasm] (R-HSA-996735)	0.483	2
UniProt:Q8QVZ0 Q8QVZ0			0.463	2
UniProt:O70445	4	Bard1 [nucleoplasm] (R-MMU-9701024) Bard1 [nucleoplasm] (R-MMU-5659775) phospho-Bard1 [nucleoplasm] (R-MMU-5659846) phospho-Bard1 [nucleoplasm] (R-MMU-9707286)	0.463	2
IntAct:EBI-1800051 CDKN1A			0.462	2
UniProt:Q7Z2E3 APTX			0.462	4

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