SUMO2-K53-DDX5

Stable Identifier
R-HSA-3900186
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Probable ATP-dependent RNA helicase DDX5 ecNumber3.6.4.13/ecNumber, DDX5_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
25218447 Uncovering global SUMOylation signaling networks in a site-specific manner

Hendriks, IA, D'Souza, RC, Yang, B, Verlaan-de Vries, M, Mann, M, Vertegaal, AC

Nat. Struct. Mol. Biol. 2014
17369852 SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1

Jacobs, AM, Nicol, SM, Hislop, RG, Jaffray, EG, Hay, RT, Fuller-Pace, FV

Oncogene 2007
25114211 Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

Impens, F, Radoshevich, L, Cossart, P, Ribet, D

Proc. Natl. Acad. Sci. U.S.A. 2014
External Reference Information
External Reference
Gene Names
DDX5, G17P1, HELR, HLR1
Chain
chain:1-614
Other Identifiers
11745795_s_at
11750815_s_at
11757332_x_at
1655
16847820
18671563
18671564
18671566
18671567
18671568
18671569
18671570
18671571
18671572
18671573
18671574
18671575
18671576
18671577
18671578
200033_at
200033_PM_at
20043
34647_at
3766895
3766896
3766899
3766900
3766912
3766914
3766916
3766918
3766920
3766922
3766924
3766926
3766927
3766929
3766936
3766937
3766938
3FE2
4A4D
5868
7892829
7892857
7893407
7893516
7893530
7894055
7894666
7894685
7894896
7895517
7896169
7896185
7896247
7896427
7896683
8017634
A_23_P15511
AAB84094
AAH16027
AAP35589
AB451257
AC009994
AF015812
AJ010931
AK297192
BAG59680
BAG70071
BC016027
BT006943
CAA09408
CAA33751
CAA36324
CAB005868
CCDS11659
CH471109
DDX5
DDX5-201
DDX5-202
EAW94202
EAW94203
ENSG00000108654
ENSP00000225792
ENSP00000403085
ENST00000225792
ENST00000450599
EntrezGene:1655
g13514826_3p_at
GE81390
GO:0000122
GO:0000166
GO:0000380
GO:0000381
GO:0000398
GO:0000956
GO:0001837
GO:0003674
GO:0003676
GO:0003723
GO:0003724
GO:0003729
GO:0003730
GO:0004004
GO:0004386
GO:0005515
GO:0005516
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005681
GO:0005730
GO:0005737
GO:0006351
GO:0006355
GO:0006357
GO:0006397
GO:0006412
GO:0006950
GO:0007165
GO:0008134
GO:0008150
GO:0008219
GO:0008380
GO:0009056
GO:0009058
GO:0009299
GO:0010501
GO:0016020
GO:0016049
GO:0016787
GO:0016887
GO:0019899
GO:0030154
GO:0030509
GO:0030520
GO:0030521
GO:0032991
GO:0034641
GO:0034655
GO:0035500
GO:0036002
GO:0040007
GO:0043021
GO:0043167
GO:0043226
GO:0043517
GO:0044403
GO:0045069
GO:0045445
GO:0045667
GO:0046332
GO:0048306
GO:0048511
GO:0048856
GO:0050681
GO:0060765
GO:0061614
GO:0070062
GO:0070412
GO:0070878
GO:0071013
GO:0072332
GO:1903800
GO:1990841
GO:1990904
GO:2001014
HGNC:2746
HPA020043
ILMN_1805344
IPR000629
IPR001650
IPR011545
IPR012587
IPR014001
IPR014014
IPR027417
IPR033488
J3KRX8
J3KRZ1
J3KTA4
J3QKN9
J3QLG9
J3QR02
J3QR62
J3QRN5
J3QRQ7
J3QS79
J3QS97
MIM:180630
NM_001320595
NM_001320596
NM_004396
NP_001307524
NP_001307525
NP_004387
PF00270
PF00271
PF08061
PH_hs_0014403
SM00487
SM00490
SM01414
TC17001800.hg
uc002jek.3
uc010wqa.2
UPI000003B456
UPI00017A73EC
X15729
X15729_s_at
X52104
X6RLV5
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (polySUMO2 [nucleoplasm]) at 53
Coordinate
53
Modification
polySUMO2 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
GeneCards
PRO
BRENDA (Homo sapiens)
PDB
HMDB Protein
Interactors (26)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9NRR4 DROSHA  1 0.737 6
 UniProt:P27958-PRO_0000037577      0.733 12
 UniProt:P04637 TP53  27 0.656 6
 UniProt:P03372 ESR1  4 0.643 4
 UniProt:P24928 POLR2A  7 0.641 3
 UniProt:Q15797 SMAD1  4 0.612 4
 UniProt:Q09472 EP300  3 0.61 4
 UniProt:O94916 NFAT5      0.591 4
 UniProt:Q13547 HDAC1  2 0.576 4
 UniProt:Q99717 SMAD5  3 0.558 3
 UniProt:Q92841 DDX17  2 0.547 3
 UniProt:P04637-7 TP53      0.544 2
 UniProt:P04637-1 TP53      0.544 2
 UniProt:P22087 FBL  1 0.543 6
 UniProt:P45481 Crebbp  2 0.524 3
 UniProt:Q01780 EXOSC10  1 0.524 3
 UniProt:P51858 HDGF  1 0.512 4
 UniProt:Q9H871 RMD5A      0.508 2
 UniProt:Q96S59 RANBP9  1 0.508 2
 UniProt:Q7L5Y9 MAEA      0.508 2
 UniProt:Q1K9H5 Q1K9H5      0.508 2
 UniProt:P62699 YPEL5  3 0.508 2
 UniProt:Q8AZK7 EBNA5      0.499 2
 UniProt:P84022 SMAD3  15 0.499 2
 UniProt:P29991-PRO_0000037946      0.488 2
 UniProt:P10085 Myod1  2 0.462 3