Reactome | SFN [cytosol]

SFN [cytosol]

Stable Identifier

R-HSA-1445105

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

14-3-3 sigma, 14-3-3 protein sigma, 1433S_HUMAN

Locations in the PathwayBrowser

Expand all

Cell Cycle (Homo sapiens)

- Cell Cycle Checkpoints (Homo sapiens)
  - G2/M Checkpoints (Homo sapiens)
    - G2/M DNA damage checkpoint (Homo sapiens)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Homo sapiens)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-1 Infection (Homo sapiens)
        
        SARS-CoV-1-host interactions (Homo sapiens)
        
        SARS-CoV-1 targets host intracellular signalling and regulatory pathways (Homo sapiens)
        
        SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to 14-3-3 proteins (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
        
        14-3-3 dimer:SUMO1-K62-p-S177-Ncap dimer [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 targets host intracellular signalling and regulatory pathways (Homo sapiens)
        
        SARS-CoV-2 N binds to 14-3-3 proteins (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
        
        14-3-3 dimer:N [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)

Programmed Cell Death (Homo sapiens)

- Apoptosis (Homo sapiens)
  - Intrinsic Pathway for Apoptosis (Homo sapiens)
    - Activation of BH3-only proteins (Homo sapiens)
      - Activation of BAD and translocation to mitochondria (Homo sapiens)
        
        Activation of BAD by calcineurin (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
        
        Sequestration of BAD protein by 14-3-3 (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase Effectors (Homo sapiens)
      - RHO GTPases activate PKNs (Homo sapiens)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
    - 14-3-3 Binds p-S237-TBC1D1 (Homo sapiens)
      - 14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
      - p-S237-TBC1D1:14-3-3 [cytosol] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
    - 14-3-3 binds p-5S,T642-AS160 (TBC1D4) (Homo sapiens)
      - 14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)
      - p-5S,T642-AS160:14-3-3:IRAP [cytoplasmic vesicle membrane] (Homo sapiens)
        
        Phospho AS160:14-3-3 [cytoplasmic vesicle membrane] (Homo sapiens)
        
        14-3-3 dimer [cytosol] (Homo sapiens)
        
        SFN dimer [cytosol] (Homo sapiens)
        
        SFN [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P31947 SFN

Gene Names

SFN, HME1

Chain

chain:1-248

Reference Genes

BioGPS Gene:2810 SFN

COSMIC (genes):SFN SFN

CTD Gene:2810 SFN

dbSNP Gene:2810 SFN

ENSEMBL:ENSG00000175793.12 SFN

HGNC:10773 SFN

KEGG Gene (Homo sapiens):2810 SFN

Monarch:2810 SFN

NCBI Gene:2810 SFN

OMIM:601290 SFN

UCSC:P31947 SFN

Reference Transcript

RefSeq:NM_006142.3 SFN

Other Identifiers

11717576_a_at

16661314

209260_PM_at

209260_at

2326775

2326776

2326777

2326778

2326779

2326780

2810

33322_3p_i_at

33322_PM_i_at

33322_i_at

33323_PM_r_at

33323_r_at

75288_at

7899265

A_14_P133833

A_23_P63254

A_33_P3389286

GE79528

GO:0000079

GO:0001836

GO:0003334

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005829

GO:0006469

GO:0006886

GO:0006913

GO:0007005

GO:0007165

GO:0008426

GO:0008630

GO:0010482

GO:0010839

GO:0012501

GO:0019901

GO:0023052

GO:0030154

GO:0030216

GO:0030307

GO:0031424

GO:0036211

GO:0042802

GO:0043154

GO:0043226

GO:0043588

GO:0043616

GO:0045296

GO:0045606

GO:0046827

GO:0048856

GO:0051219

GO:0051726

GO:0061436

GO:0070062

GO:0072089

GO:0098772

GO:2000647

HMNXSV003053202

ILMN_1806607

PH_hs_0029373

PH_hs_0030806

TC01000353.hg

X57348_s_at

g12653124_3p_at

g12653124_3p_x_at

Participates

as an output of

TP53 stimulates SFN expression (Homo sapiens)

as an input of

SFN dimerizes (Homo sapiens)

as a component of

Inferred To

14-3-3 sigma [cytosol] (Mus musculus)

Sfn [cytosol] (Rattus norvegicus)

14-3-3zeta [cytosol] (Drosophila melanogaster)

par-5 [cytosol] (Caenorhabditis elegans)

ywhaq [cytosol] (Danio rerio)

ywhaq [cytosol] (Xenopus tropicalis)

Homologues of SFN [cytosol] (Caenorhabditis elegans)

Homologues of SFN [cytosol] (Danio rerio)

fttB [cytosol] (Dictyostelium discoideum)

SFN [cytosol] (Bos taurus)

SFN [cytosol] (Caenorhabditis elegans)

SFN [cytosol] (Canis familiaris)

SFN [cytosol] (Gallus gallus)

ywhaz [cytosol] (Danio rerio)

ftt-2 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006133.1

OpenTargets

ENSG00000175793

HPA

ENSG00000175793-SFN

GeneCards

P31947

Ensembl

ENSP00000340989, ENST00000339276, ENSG00000175793

ZINC target

P31947

PRO

P31947

Pharos - Targets

P31947

PDB

6RWS, 4DHS, 3SMK, 7OBG, 7NIF, 6HN2, 6SIO, 6RM5, 5LU1, 6G8Q, 7O5D, 7NZV, 6Y3O, 4FR3, 7NK5, 7O5X, 6T80, 7NXT, 6Y3R, 6QHM, 4DHP, 3IQJ, 6Y8A, 7BAA, 3P1S, 6TJM, 7AYF, 6RKI, 6ZVE, 6FAW, 7O3P, 6TLF, 7O5G, 7OBY, 7B15, 7BKH, 7NQP, 7NVI, 7AZ1, 7OQ7, 5OEH, 3UX0, 4QLI, 6HHP, 6Y7T, 7BA9, 4FL5, 4JC3, 7NFW, 7ORT, 6RL3, 7NRL, 7BDP, 3P1N, 6YQ2, 6TM7, 3T0L, 7O5U, 5N75, 7NM9, 4Y32, 6QHL, 1YZ5, 7O3R, 6YLU, 7O5P, 3SMN, 6G6X, 6QZS, 6S3C, 6Y8D, 7OQ8, 7O6G, 7AOG, 7BGW, 6SIN, 7O6I, 7BDY, 7NN2, 7BGV, 6G8P, 6YOW, 6FI4, 6YE9, 6Y8E, 6SLW, 4Y3B, 6T5H, 6RJQ, 5N5R, 7O5S, 7NP2, 7O3S, 5OK9, 7OR7, 6RX2, 7BI3, 7NLE, 7BA8, 7BJW, 5MY9, 6QDS, 6FCP, 7OR5, 7QIK, 6S39, 7OBK, 7OQ9, 7NYG, 7NIX, 7BDT, 6RWI, 6FBB, 3SMO, 6HKF, 1YWT, 6R5L, 7NJA, 6Y3V, 6RHC, 4DHN, 6Y3S, 6XWD, 6Y8B, 3P1Q, 7OBH, 3O8I, 7AEW, 7NMH, 6RJL, 6RKM, 7BIQ, 4DHQ, 4DAT, 7NXY, 3SP5, 7OQA, 7AZ2, 6YOY, 6YP2, 7NNE, 3U9X, 7O6J, 6Y18, 6QZR, 6TL3, 3LW1, 7O34, 7NRK, 7O6K, 6G8J, 6RL6, 7NM3, 7BMC, 3SML, 7NXS, 6GHP, 7OQJ, 6TLG, 4DHT, 5OKF, 6YOX, 5LU2, 6YR7, 6SLV, 6SIP, 6Y1D, 5N5T, 6QDR, 7OR8, 7O07, 6HMU, 6RWU, 5MYC, 7NIG, 7NK3, 6YIA, 6NV2, 7NJ8, 5OM0, 4JDD, 7QIP, 7OBL, 4DHO, 6RK8, 7NV4, 6YP8, 7NXW, 7O59, 6RP6, 4DHU, 7NPG, 3P1R, 7BA3, 7ORG, 7BG3, 7BFW, 7O57, 5MHC, 4Y5I, 6S40, 7BIW, 6FBY, 7NZ6, 7B9M, 6FAU, 6TWZ, 7BA5, 6Y3W, 6Y40, 6FI5, 3P1O, 6YP3, 3MHR, 4IEA, 7OQG, 6SLX, 3T0M, 6RL4, 6ZCJ, 7OBS, 6G8I, 7NSV, 5MOC, 6XXC, 7BJB, 7BM9, 6QDU, 7NJ6, 7OB8, 7NLA, 6ZVB, 7NMA, 5HF3, 6Y58, 4DHM, 3SMM, 7NYE, 7OB5, 6W0L, 6G8L, 7NMX, 6XY5, 7NZG, 7OBX, 6Y1J, 6FAV, 7O5C, 7NPB, 7O3A, 7BJL, 7O3F, 6S9Q, 6FBW, 5LTW, 7O6M, 3IQV, 7OBT, 7O6O, 6RJZ, 7BIY, 6QDT, 6HKB, 6Y3M, 6YIC, 7B13, 6ZVC, 6YIB, 7OQU, 5BTV, 7AXN, 7ORH, 6RWH, 7NJB, 3SPR, 6ZVD, 7OQS, 6RKK, 7BA6, 7OPW, 6Y44, 6T5F, 3P1P, 6TCH, 6YR6, 6YPL, 4DHR, 7O6F, 7NM1, 5OEG, 7OBD, 7NIZ, 6RM7, 7NY4, 7O5A, 7B9T, 7BGQ, 3IQU, 7OBC, 4DAU, 6QIU, 7NWS, 7BA7, 7B9R, 7NND, 7ORS, 7NJ9, 6SIQ, 6YPY, 7OQW, 7NZK, 7O3Q, 7O5O, 7BAB, 7OR3, 7BGR, 5MXO, 6G8K, 7NR7, 7O5F, 6YR5, 7NMW, 7BJF, 7NYF, 5N5W, 6HMT, 5OMA

Interactors (46)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.833	9
UniProt:P04049 RAF1	20	p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098)	0.822	6
UniProt:Q92934 BAD	4	p-S99-BAD [cytosol] (R-HSA-198335) BAD [cytosol] (R-HSA-50662) BAD [mitochondrial outer membrane] (R-HSA-114242) p-S91-BAD [cytosol] (R-HSA-217297)	0.804	6
UniProt:Q8NHY2 COP1	3	p-S387-RFWD2 [cytosol] (R-HSA-349439) RFWD2 [nucleoplasm] (R-HSA-349454) p-S387-RFWD2 [nucleoplasm] (R-HSA-349450)	0.718	6
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.713	5
UniProt:Q8WUI4 HDAC7	1	HDAC7 [nucleoplasm] (R-HSA-3004534)	0.688	3
UniProt:P56524 HDAC4	3	polySUMO2,3-K559-HDAC4 [nucleoplasm] (R-HSA-4616029) monoSUMO1-K559-HDAC4 [nucleoplasm] (R-HSA-4616016) HDAC4 [nucleoplasm] (R-HSA-351581)	0.678	4
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.675	4
UniProt:P10398 ARAF	4	p-S299,S302,T452,T455,S582 ARAF [cytosol] (R-HSA-5672646) p-S299,S302,T452,T455,S582 ARAF [plasma membrane] (R-HSA-5672648) p-S582 ARAF [cytosol] (R-HSA-5672681) p-S214,S582 ARAF [cytosol] (R-HSA-5672639)	0.669	3
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.669	3
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.667	4
UniProt:P51946 CCNH	1	CCNH [nucleoplasm] (R-HSA-69220)	0.666	4
UniProt:Q96HA8 NTAQ1			0.666	4
UniProt:Q7L5N1 COPS6	2	COPS6 [nucleoplasm] (R-HSA-5697026) COPS6 [cytosol] (R-HSA-416961)	0.653	7
UniProt:Q5T1R4 HIVEP3	1	HIVEP3 [cytosol] (R-HSA-9008029)	0.618	5
UniProt:P78559 MAP1A			0.611	3
UniProt:Q14103-4 HNRNPD	2	HNRNPD-4 [cytosol] (R-HSA-450442) Ub-HNRNPD-4 [cytosol] (R-HSA-451232)	0.602	7
UniProt:P27448 MARK3	1	MARK3 [cytosol] (R-HSA-5672591)	0.573	2
UniProt:O60269 GRIN2			0.573	2
UniProt:P15056 BRAF	20	p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620)	0.564	3
UniProt:Q9Y2U5 M3K2			0.564	2
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.564	2
UniProt:Q13470 TNK1			0.564	2
UniProt:P30305 CDC25B	3	p-S50,T69,S160,S321,S470-CDC25B [cytosol] (R-HSA-8863644) CDC25B [cytosol] (R-HSA-157412) CDC25B [nucleoplasm] (R-HSA-69734)	0.564	2
UniProt:P10636-2 MAPT			0.558	2
UniProt:Q13064 MKRN3			0.556	3
UniProt:Q86Z20 CC125			0.556	3
UniProt:Q9NYF3 FA53C			0.556	3
UniProt:Q96QF0 RAB3IP	1	RAB3IP [cytosol] (R-HSA-5617610)	0.556	3
UniProt:P98177 FOXO4	8	FOXO4 [nucleoplasm] (R-HSA-5690183) p-T32,S197,S262-FOXO4 [nucleoplasm] (R-HSA-199314) p-T32,S197,S262-FOXO4 [cytosol] (R-HSA-9614415) SOH-C481-FOXO4 [nucleoplasm] (R-HSA-9617655) CREBBP-S-S-FOXO4 [nucleoplasm] (R-HSA-9617679) EP300-S-S-FOXO4 [nucleoplasm] (R-HSA-9617681) Ac-K-FOXO4 [nucleoplasm] (R-HSA-9617761) PolyUb-FOXO4 [nucleoplasm] (R-HSA-6782501)	0.556	3
UniProt:Q17RB8 LONRF1	1	LONRF1 [cytosol] (R-HSA-8850905)	0.556	3
UniProt:Q68D86 C102B			0.556	3
UniProt:Q8IZU0 FAM9B			0.556	3
UniProt:Q03373 DIG2			0.556	3
UniProt:Q53FD0 ZC21C			0.556	3
UniProt:P43355 MAGA1			0.556	3
UniProt:P55771 PAX9			0.556	3
UniProt:Q9UJM3 ERRFI			0.556	3
UniProt:Q9UQL6 HDAC5	1	HDAC5 [nucleoplasm] (R-HSA-3004533)	0.547	3
UniProt:Q8NFH8 REPS2	1	REPS2 [cytosol] (R-HSA-432938)	0.544	2
UniProt:Q9UQC2 GAB2	5	p-Y643-GAB2 [cytosol] (R-HSA-9677149) p-5Y-GAB2 [cytosol] (R-HSA-8855574) p-Y-GAB2 [cytosol] (R-HSA-912529) p-Y452,Y476,Y584-GAB2 [cytosol] (R-HSA-2685615) GAB2 [cytosol] (R-HSA-508239)	0.527	3
UniProt:Q96IF1 AJUBA	3	AJUBA [cytosol] (R-HSA-2564698) p-S-AJUBA [cytosol] (R-HSA-2574841) AJUBA [nucleoplasm] (R-HSA-5687935)	0.524	2
UniProt:O00444 PLK4	1	PLK4 [cytosol] (R-HSA-380286)	0.508	2
UniProt:P00519 ABL1	5	p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) ABL1 [cytosol] (R-HSA-375987) p-Y226,Y393-ABL1 [cytosol] (R-HSA-8942610) ABL1 [nucleoplasm] (R-HSA-5686579) p-S456-ABL1 [nucleoplasm] (R-HSA-5686576)	0.499	2
UniProt:Q51451 Q51451			0.469	2
UniProt:P06493 CDK1	10	CDK1 [endoplasmic reticulum membrane] (R-HSA-264424) p-T14,T161-CDK1 [nucleoplasm] (R-HSA-170078) p-T14-CDK1 [nucleoplasm] (R-HSA-170045) p-T14-CDK1 [cytosol] (R-HSA-170064) CDK1 [nucleoplasm] (R-HSA-68889) CDK1 [cytosol] (R-HSA-170075) p-T14,Y15,T161-CDK1 [cytosol] (R-HSA-170071) p-T161-CDK1 [cytosol] (R-HSA-157415) p-T14,Y15,T161-CDK1 [nucleoplasm] (R-HSA-170074) p-T161-CDK1 [nucleoplasm] (R-HSA-170066)	0.463	2

Cite Us!