Reactome will be unavailable due to host maintenance from Friday, April 27 at 6pm to Sunday, April 29 at 11:55pm.

During the outage, you may wish to use our mirror site at reactome.ncpsb.org.

USP7

Stable Identifier
R-HSA-3215278
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
HAUSP, Ubiquitin carboxyl-terminal hydrolase 7, Deubiquitinating enzyme 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin thioesterase 7, Ubiquitin-specific-processing protease 7
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
USP7, HAUSP
Chain
chain:1-1102
Other Identifiers
0006180292
11725060_s_at
11725061_a_at
11725062_at
11748350_a_at
11752485_a_at
15641
16823756
1NB8
1NBF
1YY6
1YZE
201498_at
201499_s_at
222032_s_at
2F1W
2F1X
2F1Y
2F1Z
2FOJ
2FOO
2FOP
2KVR
2XXN
2YLM
37672_at
3MQR
3MQS
4JJQ
4KG9
4M5W
4M5X
4PYZ
4WPH
4WPI
4YOC
4YSI
4Z96
4Z97
5C56
5C6D
5FWI
5GG4
5J7T
5JTJ
5JTV
7874
7999326
8108
88975_at
A_23_P49481
A_24_P245108
AC022167
AK302771
BAH13801
CAA96580
CAB008108
CCDS32385
CCDS66941
CH471112
EAW85194
ENSG00000187555
ENSP00000343535
ENSP00000371310
ENST00000344836
ENST00000381886
EntrezGene:7874
g4507856_3p_a_at
GE60431
GE86510
GO:0002039
GO:0004197
GO:0004843
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006281
GO:0006283
GO:0006508
GO:0006511
GO:0006974
GO:0007275
GO:0008022
GO:0008134
GO:0008233
GO:0008234
GO:0010216
GO:0016032
GO:0016567
GO:0016579
GO:0016604
GO:0016605
GO:0016787
GO:0031625
GO:0032088
GO:0035520
GO:0035616
GO:0036459
GO:0050821
GO:0051090
GO:1904353
HGNC:12630
HPA015641
Hs.129663.0.A1_3p_at
Hs.386939
Hs.78683.0.S2_3p_at
ILMN_1729319
IPR001394
IPR002083
IPR008974
IPR018200
IPR024729
IPR028889
IPR029346
NM_001286457
NM_001286458
NM_001321858
NM_003470
NP_001273386
NP_001273387
NP_001308787
NP_003461
NR_135826
PF00443
PF00917
PF12436
PF14533
PH_hs_0024406
PH_hs_0038530
SM00061
TC16000852.hg
uc002czk.4
uc002czl.2
UPI000013F0BE
UPI000059D30E
USP7
USP7-201
USP7-202
XM_017023652
XM_017023653
XP_016879141
XP_016879142
Z72499
Z72499_at
Participant Of
Other forms of this molecule
Inferred To
Cross References
Brenda
ZINC - Substances
GeneCards
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (39)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04637 TP53  27 0.968 22
 UniProt:Q00987 MDM2  10 0.959 27
 UniProt:P03211 EBNA1      0.811 7
 UniProt:Q9UER7 DAXX  1 0.742 13
 UniProt:P08393 ICP0      0.734 4
 IntAct:EBI-4399559 UBIQ      0.73 3
 UniProt:O15151 MDM4  5 0.711 15
 UniProt:F5H9D8 F5H9D8      0.702 13
 UniProt:Q99496 RNF2  1 0.688 5
 UniProt:P51784 USP11  1 0.669 3
 UniProt:Q9UQR0 SCML2      0.669 3
 UniProt:P26358 DNMT1  1 0.669 3
 UniProt:Q06587 RING1  1 0.656 5
 UniProt:P35226 BMI1  3 0.646 7
 UniProt:O35618  5 0.641 4
 UniProt:Q9HC52 CBX8  1 0.623 7
 UniProt:P60484-1 PTEN      0.602 5
 UniProt:P35227 PCGF2  1 0.591 5
 UniProt:Q86VY4 TSYL5      0.591 4
 UniProt:P84022 SMAD3  15 0.573 2
 UniProt:P06400 RB1  3 0.571 8
 UniProt:Q7Z6Z7 HUWE1  4 0.564 2
 UniProt:Q6PIJ6 FBX38      0.564 2
 UniProt:P33991 MCM4  1 0.564 2
 UniProt:Q96EI5 TCAL4      0.564 3
 UniProt:Q8WUA2 PPIL4  1 0.564 2
 UniProt:P49915 GMPS  1 0.564 2
 UniProt:Q6W2J9 BCOR      0.547 3
 UniProt:Q86SQ0 PHLB2      0.547 2
 UniProt:P42166 TMPO      0.547 2
 UniProt:Q99836 MYD88  9 0.543 3
 UniProt:P21145 MAL      0.543 3
 UniProt:Q9BSM1 PCGF1      0.527 2
 UniProt:Q5U5Q3 MEX3C  1 0.524 3
 UniProt:Q99426 TBCB  1 0.508 2
 UniProt:Q77UV9 Q77UV9      0.499 2
 UniProt:Q49AR9 Q49AR9      0.488 2
 UniProt:P36508 ZNF76      0.488 2
 UniProt:P46531 NOTCH1  60 0.462 2