Reactome | SAFB [nucleoplasm]

SAFB [nucleoplasm]

Stable Identifier

R-HSA-4085379

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Scaffold attachment factor B1, SAFB1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15424 SAFB

Gene Names

SAFB, HAP, HET, SAFB1

Chain

initiator methionine:, chain:2-915

Reference Genes

BioGPS Gene:6294 SAFB

COSMIC (genes):SAFB SAFB

CTD Gene:6294 SAFB

dbSNP Gene:6294 SAFB

ENSEMBL:ENSG00000160633 SAFB

ENSEMBL_homo_sapiens_GENE:ENSG00000160633.13 SAFB

HGNC:10520 SAFB

KEGG Gene (Homo sapiens):6294 SAFB

Monarch:6294 SAFB

NCBI Gene:6294 SAFB

OMIM:602895 SAFB

UCSC:Q15424 SAFB

Reference Transcript

Other Identifiers

11722360_a_at

11747271_a_at

11756438_a_at

16857315

201747_PM_s_at

201747_s_at

201748_PM_s_at

201748_s_at

3353332

3817985

3817986

3817987

3817990

3817993

3817994

3817995

3817997

3818000

3818001

3818002

3818004

3818005

3818006

3818010

3818011

3818012

3818013

3818014

3818017

3818018

3818021

3818022

3818027

3818029

3818031

3818033

3818034

3847290

3847291

41316_s_at

6294

8024936

A_14_P124343

A_33_P3220818

GE61262

GO:0000978

GO:0003676

GO:0003677

GO:0003682

GO:0003690

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0006325

GO:0006351

GO:0006355

GO:0006357

GO:0016071

GO:0023052

GO:0030496

GO:0030520

GO:0043226

GO:0043565

GO:0050684

HMNXSV003053663

Hs.23978.0.S1_3p_a_at

ILMN_1722059

L43631_at

TC19000102.hg

TC19001950.hg

g4506778_3p_a_at

Participates

as an input of

Other forms of this molecule

polySUMO2,3-K231,K294-SAFB [nucleoplasm]

monoSUMO1-K231,K294-SAFB [nucleoplasm]

Inferred To

Safb [nucleoplasm] (Mus musculus)

Safb [nucleoplasm] (Rattus norvegicus)

safb [nucleoplasm] (Danio rerio)

SAFB [nucleoplasm] (Bos taurus)

SAFB [nucleoplasm] (Canis familiaris)

SAFB [nucleoplasm] (Gallus gallus)

SAFB [nucleoplasm] (Sus scrofa)

phm-2 [nucleoplasm] (Caenorhabditis elegans)

Saf-B [nucleoplasm] (Drosophila melanogaster)

Homologues of SAFB [nucleoplasm] (Gallus gallus)

Cross References

RefSeq

NP_002958.2, NP_001188267.1, NP_001307501.1, NP_001188269.1, NP_001307500.1, NP_001188268.1

OpenTargets

ENSG00000160633

HPA

ENSG00000160633-SAFB

GeneCards

Q15424

Ensembl

ENST00000454510, ENSG00000160633, ENST00000292123, ENST00000592224, ENSP00000464840, ENST00000588852, ENSP00000415895, ENSP00000292123, ENSP00000467423

PRO

Q15424

Pharos - Targets

Q15424

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35637 FUS	1	FUS [nucleoplasm] (R-HSA-72040)	0.727	8
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.556	5
UniProt:Q9GZQ8 MAP1LC3B	3	MAP1LC3B [autophagosome membrane] (R-HSA-5683641) MAP1LC3B(2-121) [cytosol] (R-HSA-5682674) MAP1LC3B [cytosol] (R-HSA-5205651)	0.547	3
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	5
UniProt:Q96SB4-3 SRPK1			0.524	2
UniProt:Q96SB4-2 SRPK1			0.524	2
UniProt:Q14151 SAFB2			0.508	3
UniProt:Q9JKL7 SREK1			0.499	3
UniProt:P09651 HNRNPA1	2	HNRNPA1 [cytosol] (R-HSA-9727902) HNRNPA1 [nucleoplasm] (R-HSA-71927)	0.483	2
UniProt:Q16630 CPSF6	2	CPSF6(1-490)-p-FGFR1(429-822) fusion [cytosol] (R-HSA-1838987) CPSF6(1-490)-FGFR1(429-822) fusion [cytosol] (R-HSA-1614368)	0.483	2

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