MDM2

Stable Identifier
R-HSA-198644
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein) (Hdm2), Ubiquitin-protein ligase E3 Mdm2 , p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
MDM2
Chain
chain:1-491
Other Identifiers
0000070278
0002320113
0002690017
11731564_x_at
11731565_x_at
11731566_a_at
11731567_a_at
11731568_x_at
11753563_x_at
11753688_a_at
11753689_x_at
11753819_a_at
11753820_x_at
11756046_x_at
16303
16753853
1859_s_at
1880_at
1RV1
1T4E
1T4F
1YCR
1Z1M
2008_s_at
205386_s_at
211832_s_at
217373_x_at
217542_at
225160_x_at
229711_s_at
238733_at
244616_3p_x_at
244616_x_at
2AXI
2C6A
2C6B
2F1Y
2FOP
2GV2
2HDP
2LZG
2M86
2MPS
2RUH
2VJE
2VJF
3421302
3421303
3421304
3421305
3421306
3421307
3421310
3421311
3421315
3421316
3421322
3421323
3421325
3421328
3421329
3421334
3421335
3421336
3421337
3421338
3421339
3421340
3421341
3421342
3421343
3421344
3421345
3421346
3421347
3421348
3421349
3421350
3421351
3421361
38509_at
3979479
3EQS
3G03
3IUX
3IWY
3JZK
3JZR
3JZS
3LBK
3LBL
3LNJ
3LNZ
3MQS
3TJ2
3TPX
3TU1
3V3B
3VBG
3VZV
3W69
4193
46744_s_at
4DIJ
4ERE
4ERF
4HBM
4HFZ
4HG7
4JV7
4JV9
4JVE
4JVR
4JWR
4MDN
4MDQ
4OAS
4OBA
4OCC
4ODE
4ODF
4OGN
4OGT
4OGV
4OQ3
4QO4
4QOC
4UD7
4UE1
4UMN
4WT2
4XXB
4ZFI
4ZGK
4ZYC
4ZYF
4ZYI
53464_at
5AFG
5C5A
5HMH
5HMI
5HMK
5J7F
5J7G
5LAV
5LAW
5LAY
5LAZ
5LN2
5MNJ
5SWK
5TRF
61888_at
62280_at
64992_i_at
64993_r_at
75871_at
7956989
86
A7UKX8
A_14_P118388
A_14_P133404
A_14_P135914
A_23_P139895
A_23_P309545
A_23_P502750
A_24_P925664
A_33_P3361707
AAA60568
AAA75514
AAA75515
AAA75516
AAA75517
AAA75518
AAA82061
AAA82237
AAF42995
AAL40179
AAL40180
AAM78554
AAP35922
AC025423
AF092844
AF092845
AF201370
AF527840
AJ251943
AK290341
BAF83030
BC009893
BT007258
CAA78055
CAB000086
CAB016303
CAB64448
CCDS61189
CCDS8986
E5RJQ0
ENSG00000135679
ENSP00000258149
ENSP00000299252
ENSP00000353611
ENSP00000377065
ENST00000258149
ENST00000299252
ENST00000360430
ENST00000393413
EntrezGene:4193
F5GZC3
F5H1M7
G3XA89
g7230489_3p_s_at
GE58146
GE832699
GE83502
GO:0000122
GO:0000278
GO:0001568
GO:0001974
GO:0002027
GO:0002039
GO:0003013
GO:0003170
GO:0003181
GO:0003203
GO:0003281
GO:0003283
GO:0003674
GO:0003723
GO:0004842
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0005886
GO:0006464
GO:0006511
GO:0006810
GO:0006913
GO:0006950
GO:0006977
GO:0007049
GO:0007089
GO:0007165
GO:0007507
GO:0008097
GO:0008150
GO:0008219
GO:0008270
GO:0008283
GO:0008284
GO:0009056
GO:0009058
GO:0009636
GO:0010039
GO:0010468
GO:0010628
GO:0010629
GO:0010955
GO:0010977
GO:0016032
GO:0016567
GO:0016579
GO:0016604
GO:0016740
GO:0016874
GO:0016925
GO:0018205
GO:0019789
GO:0019843
GO:0019899
GO:0019904
GO:0022607
GO:0030154
GO:0030666
GO:0031410
GO:0031625
GO:0031648
GO:0032026
GO:0032436
GO:0032991
GO:0034504
GO:0034641
GO:0036369
GO:0040011
GO:0042176
GO:0042220
GO:0042493
GO:0042802
GO:0042975
GO:0043021
GO:0043066
GO:0043154
GO:0043167
GO:0043226
GO:0043278
GO:0043491
GO:0043518
GO:0044403
GO:0045184
GO:0045202
GO:0045472
GO:0045787
GO:0045892
GO:0045931
GO:0046677
GO:0046827
GO:0046872
GO:0047485
GO:0048545
GO:0048856
GO:0048870
GO:0051603
GO:0051604
GO:0051865
GO:0060411
GO:0061630
GO:0061663
GO:0065003
GO:0070301
GO:0071157
GO:0071236
GO:0071301
GO:0071310
GO:0071312
GO:0071363
GO:0071375
GO:0071391
GO:0071407
GO:0071456
GO:0071480
GO:0071494
GO:0072717
GO:0097110
GO:0097718
GO:1901796
GO:1901797
GO:1902254
GO:1904404
GO:1904707
GO:1904754
GO:1990000
GO:1990785
HGNC:6973
Hs.116932.0.A1_3p_at
Hs.168732.0.A1_3p_at
Hs.168732.0.A1_3p_x_at
Hs.272346.0.S1_3p_s_at
Hs.332938.1.S1_3p_a_at
Hs.37494.0.A1_3p_at
ILMN_1736829
ILMN_1814208
ILMN_2389851
IPR001841
IPR001876
IPR003121
IPR013083
IPR015459
IPR016495
IPR028340
IPR036443
IPR036885
J3KN53
M92424
M92424_at
MDM2
MDM2-202
MDM2-203
MDM2-207
MDM2-210
MIM:164785
MIM:614401
NM_001145340
NM_001278462
NM_002392
NP_001138812
NP_001265391
NP_002383
PF00641
PF02201
PF13920
PH_hs_0023082
Q8NDW1
Q8TE47
Q96DS5
Q9H4C3
Q9H4C5
TC12000606.hg
TC12002437.hg
U28935
U33199
U33200
U33201
U33202
U33202_s_at
U33203
U33203_s_at
U39736
uc001sui.6
uc058qrs.1
uc058qru.1
uc058qrw.1
UPI000002ADC4
UPI000002ADC6
UPI000002ADC7
UPI00006CA35C
Z12020
Participant Of
Other forms of this molecule
Inferred To
Interactors (69)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04637 TP53  27 0.994 96
 UniProt:Q93009 USP7  2 0.959 27
 UniProt:O15151 MDM4  5 0.932 13
 UniProt:P62913 RPL11  1 0.912 11
 UniProt:Q9UER7 DAXX  2 0.895 18
 UniProt:P31749 AKT1  13 0.828 6
 UniProt:P0CG48 UBC  316 0.821 6
 UniProt:Q8N726 CDKN2A  1 0.813 5
 UniProt:P62081 RPS7  2 0.75 15
 UniProt:Q00987 MDM2  11 0.736 4
 UniProt:P06400 RB1  3 0.734 5
 UniProt:P19338 NCL  1 0.71 8
 UniProt:P68104 EEF1A1  6 0.709 9
 UniProt:P32121 ARRB2  2 0.708 5
 UniProt:P06748 NPM1  5 0.697 5
 UniProt:P23396 RPS3  2 0.696 8
 UniProt:P29067  2 0.688 4
 UniProt:P46777 RPL5  1 0.669 5
 UniProt:O96017 CHEK2  3 0.66 6
 UniProt:P49407 ARRB1  5 0.641 3
 UniProt:Q96FW1 OTUB1  2 0.632 5
 UniProt:P49757 NUMB  1 0.623 6
 UniProt:Q9H2X6 HIPK2  3 0.62 5
 UniProt:Q71UM5 RPS27L  2 0.619 6
 IntAct:EBI-15762335 PMI      0.618 3
 UniProt:Q8N488 RYBP  1 0.616 11
 UniProt:P61289 PSME3  2 0.612 8
 UniProt:P26447 S10A4      0.611 3
 UniProt:P48730 CSNK1D  3 0.61 6
 UniProt:P42574 CASP3  5 0.609 2
 UniProt:P29590 PML  5 0.609 6
 IntAct:EBI-4399559 UBIQ      0.609 2
 UniProt:P53350 PLK1  4 0.602 7
 UniProt:P42677 RPS27  2 0.602 5
 UniProt:Q9Y297 BTRC  2 0.591 9
 UniProt:P08069 IGF1R  3 0.589 2
 UniProt:P61978 HNRNPK  2 0.589 2
 UniProt:P29590-5 PML      0.582 6
 UniProt:P62829 RPL23  1 0.573 3
 UniProt:O15350 TP73  3 0.558 4
 UniProt:P23297 S100A1  1 0.558 2
 UniProt:P04271 S100B  1 0.558 2
 UniProt:P29034 S10A2      0.558 2
 UniProt:Q13362 PPP2R5C  3 0.558 5
 UniProt:P06703 S10A6      0.558 2
 UniProt:Q9NVN8 GNL3L      0.556 8
 UniProt:O15297 PPM1D  1 0.544 4
 UniProt:P60866 RPS20  2 0.527 2
 UniProt:P78352 DLG4  3 0.525 3
 UniProt:P17535 JUND  1 0.524 3
 UniProt:P15311 EZR  3 0.524 3
 UniProt:Q9UKB1 FBXW11  1 0.524 4
 UniProt:Q13616 CUL1  3 0.524 3
 UniProt:Q2HR73 VIRF4      0.524 2
 UniProt:P48729-2 CSNK1A1      0.524 3
 UniProt:Q15648 MED1  1 0.524 3
 UniProt:Q92736 RYR2  1 0.524 2
 UniProt:P48729 CSNK1A1  2 0.524 3
 UniProt:Q5T7V8 GORAB      0.524 6
 UniProt:P49674 CSNK1E  2 0.524 3
 UniProt:Q15466 NR0B2  1 0.524 4
 UniProt:P05412 JUN  4 0.524 3
 UniProt:P03372 ESR1  4 0.508 2
 UniProt:Q00688 FKBP3      0.508 2
 UniProt:Q6PCD5 RFWD3      0.499 2
 UniProt:Q9NS23 RASF1      0.499 5
 UniProt:Q6P5F9  2 0.499 4
 UniProt:Q13362-1 PPP2R5C      0.499 3
 IntAct:EBI-1800051 CDKN1A      0.462 2