Reactome | NOC2L [nucleoplasm]

NOC2L [nucleoplasm]

Stable Identifier

R-HSA-3222129

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Nucleolar complex protein 2 homolog, Novel INHAT repressor, NIR

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y3T9 NOC2L

Gene Names

NOC2L, NIR

Chain

chain:1-749

Reference Genes

BioGPS Gene:26155 NOC2L

COSMIC (genes):NOC2L NOC2L

CTD Gene:26155 NOC2L

dbSNP Gene:26155 NOC2L

ENSEMBL:ENSG00000188976 NOC2L

HGNC:24517 NOC2L

KEGG:hsa:26155 NOC2L

Monarch:26155 NOC2L

NCBI Gene:26155 NOC2L

OMIM:610770 NOC2L

UCSC:Q9Y3T9 NOC2L

Reference Transcript

Other Identifiers

11746519_x_at

11757561_s_at

1559139_3p_at

1559139_PM_at

1559139_at

16679994

202115_PM_s_at

202115_s_at

2505421

2505422

2505426

2505427

2505430

2505432

2505433

2505434

2505437

2505438

2505439

2505441

2505442

2576530

2576532

2576533

2576534

2576536

2576538

2576542

2576544

26155

4054638

4054640

4054641

4054642

4054643

4054644

4054645

4054646

4054647

4054648

4054649

4054650

4054651

4054652

4054653

4054658

4054659

4054660

4054661

4054662

4054663

4054664

4054665

4054667

4054668

4054669

4054670

4054671

4054672

4054673

4054674

41861_at

63975_s_at

68474_at

7911359

A_23_P138058

A_24_P917951

GE56228

GO:0000122

GO:0002903

GO:0003682

GO:0003714

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005829

GO:0006325

GO:0006355

GO:0006915

GO:0012501

GO:0030690

GO:0030691

GO:0031491

GO:0034644

GO:0042273

GO:0042393

GO:0043226

GO:0045815

GO:0060090

GO:0140110

GO:0140297

GO:2001243

HMNXSV003036570

Hs2.282541.1.S1_3p_at

Hs2.282541.1.S1_3p_x_at

ILMN_1792820

TC01002078.hg

g7661605_3p_a_at

Participates

as a component of

as an input of

NOC2L binds TP53 (Homo sapiens)

Inferred To

Noc2 [nucleoplasm] (Drosophila melanogaster)

Noc2l [nucleoplasm] (Mus musculus)

Noc2l [nucleoplasm] (Rattus norvegicus)

noc2l [nucleoplasm] (Xenopus tropicalis)

NOC2L [nucleoplasm] (Bos taurus)

NOC2L [nucleoplasm] (Canis familiaris)

NOC2L [nucleoplasm] (Dictyostelium discoideum)

NOC2L [nucleoplasm] (Gallus gallus)

NOC2L [nucleoplasm] (Plasmodium falciparum)

NOC2L [nucleoplasm] (Schizosaccharomyces pombe)

NOC2L [nucleoplasm] (Sus scrofa)

NOC2 [nucleoplasm] (Saccharomyces cerevisiae)

pro-2 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_056473.2, NP_056473.3

OpenTargets

ENSG00000188976

ENSEMBL

ENSP00000317992, ENST00000327044, ENSG00000188976

HPA

ENSG00000188976-NOC2L

GeneCards

NOC2L

PRO

Q9Y3T9

Pharos - Targets

Q9Y3T9

GlyGen

Q9Y3T9

PDB

8FKY, 8FKW, 8FKX, 8FKV

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q07020 RPL18	1	RPL18 [cytosol] (R-HSA-72420)	0.643	4
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.632	8
UniProt:P62277 RPS13	2	RPS13 [cytosol] (R-HSA-72331) RPS13 [nucleoplasm] (R-HSA-6791198)	0.527	3
UniProt:Q6DKI1 RL7L			0.527	3
UniProt:P01127 PDGFB	8	PDGFB (82-190) [extracellular region] (R-HSA-184201) PDGFB(82-241) [extracellular region] (R-HSA-381904) PDGFB(1-241) [endoplasmic reticulum lumen] (R-HSA-381903) PDGFB(1-241) [Golgi membrane] (R-HSA-380740) PDGFB(1-81) [Golgi lumen] (R-HSA-389058) PDGFB(191-241) [Golgi lumen] (R-HSA-396945) PDGFB(21-81) [platelet alpha granule lumen] (R-HSA-184200) PDGFB(82-241) [platelet alpha granule lumen] (R-HSA-387075)	0.527	2
UniProt:P78362 SRPK2	1	SRPK2 [cytosol] (R-HSA-9729332)	0.527	2
UniProt:P40429 RPL13A	2	RPL13A [cytosol] (R-HSA-72412) p-RPL13A [cytosol] (R-HSA-156829)	0.527	4
UniProt:P46779 RPL28	1	RPL28 [cytosol] (R-HSA-72444)	0.527	2
UniProt:Q96ME7 ZN512			0.527	2
UniProt:Q96LZ2 MAGBA			0.527	2
UniProt:O43159 RRP8	1	RRP8 [nucleoplasm] (R-HSA-427524)	0.527	3
UniProt:P84098 RPL19	1	RPL19 [cytosol] (R-HSA-72424)	0.527	3
UniProt:P62263 RPS14	2	RPS14 [cytosol] (R-HSA-72333) RPS14 [nucleoplasm] (R-HSA-6790669)	0.527	2
UniProt:Q96FN4 CPNE2			0.527	2
UniProt:Q53GL0 PKHO1			0.527	2
UniProt:Q9BXY0 MAK16			0.527	3
UniProt:Q9NY72 SCN3B	1	SCN3B [plasma membrane] (R-HSA-197921)	0.527	2
UniProt:Q02543 RPL18A	1	RPL18A [cytosol] (R-HSA-72422)	0.527	2
UniProt:P51608 MECP2			0.527	3
UniProt:P42696 RBM34			0.527	2
UniProt:P11487 FGF3	1	FGF3 [extracellular region] (R-HSA-189886)	0.527	2
UniProt:O15265 ATXN7	2	ATXN7 [cytosol] (R-HSA-201591) ATXN7 [nucleoplasm] (R-HSA-8869458)	0.508	2
UniProt:Q8WYQ5 DGCR8	1	DGCR8 [nucleoplasm] (R-HSA-1482509)	0.483	2
UniProt:P62753 RPS6	4	RPS6 [cytosol] (R-HSA-72381) p-5S-RPS6 [cytosol] (R-HSA-165727) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) RPS6 [nucleoplasm] (R-HSA-6790606)	0.483	2

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