p-5Y-PTK2 [cytosol]

Stable Identifier
R-HSA-5218711
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-5Y-FAK1, p(Y397,576,577,861,925)-FAK 1
p-5Y-PTK2 [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
12387730 Site-specific phosphorylation of platelet focal adhesion kinase by low-density lipoprotein

Akkerman, JW, Relou, IA, Bax, LA, van Rijn, HJ

Biochem J 2003
External Reference Information
External Reference
Gene Names
PTK2, FAK, FAK1
Chain
initiator methionine:, chain:2-1052
Other Identifiers
11716373_a_at
11716374_s_at
11747793_a_at
207821_PM_s_at
207821_s_at
208820_PM_at
208820_at
312_s_at
3156306
3156308
3156309
3156310
3156313
3156315
3156322
3156324
3156328
3156338
3156339
3156342
3156345
3156357
3156358
3156360
3156362
3156366
3156373
3156375
3156377
3156387
3156388
3156392
3156393
3156396
3156397
3156400
3156402
3156404
3156410
3156420
3156425
3156435
3156457
3156464
3156465
36117_at
52392_s_at
5747
8153223
A_23_P22096
A_23_P324679
A_23_P72050
GE79453
GE85906
GO:0000166
GO:0001525
GO:0001725
GO:0001890
GO:0001932
GO:0001934
GO:0002376
GO:0003007
GO:0003779
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0004725
GO:0005178
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0005925
GO:0005929
GO:0005938
GO:0006468
GO:0007010
GO:0007155
GO:0007163
GO:0007166
GO:0007172
GO:0007173
GO:0007179
GO:0007229
GO:0007411
GO:0008092
GO:0008284
GO:0008360
GO:0008432
GO:0010033
GO:0010594
GO:0010632
GO:0010634
GO:0010718
GO:0010759
GO:0010763
GO:0012501
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0016787
GO:0018108
GO:0019901
GO:0019903
GO:0022408
GO:0023052
GO:0030010
GO:0030054
GO:0030154
GO:0030155
GO:0030163
GO:0030335
GO:0033628
GO:0034330
GO:0035995
GO:0036064
GO:0036211
GO:0038007
GO:0038096
GO:0042060
GO:0042127
GO:0042169
GO:0042995
GO:0043066
GO:0043087
GO:0043197
GO:0043226
GO:0043231
GO:0045667
GO:0045860
GO:0046777
GO:0048010
GO:0048013
GO:0048471
GO:0048856
GO:0048870
GO:0051128
GO:0051239
GO:0051493
GO:0051893
GO:0051897
GO:0060396
GO:0065003
GO:0065008
GO:0070161
GO:0090303
GO:0098772
GO:0120041
GO:0140096
GO:0140677
GO:1900024
GO:1902531
GO:2000060
GO:2000811
HMNXSV003030583
Hs.740.1.S2_3p_at
Hs.740.1.S2_3p_x_at
ILMN_1676305
ILMN_1714364
PH_hs_0025321
g5032000_3p_a_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
O4'-phospho-L-tyrosine at 397
Coordinate
397
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 576
Coordinate
576
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 577
Coordinate
577
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 861
Coordinate
861
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 925
Coordinate
925
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
ZINC - Metabolites
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (32)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P49023 PXN  4 0.942 19
 UniProt:P12931 SRC  6 0.924 9
 UniProt:P04637 TP53  20 0.751 13
 UniProt:P00533 EGFR  20 0.745 7
 UniProt:P05480 Src  13 0.683 5
 UniProt:O43294 TGFI1      0.678 3
 UniProt:O60711 LPXN      0.659 4
 UniProt:P62993 GRB2  1 0.659 4
 UniProt:Q9H3S7 PTPN23  1 0.639 4
 UniProt:P46108 CRK  1 0.635 3
 UniProt:Q92569 PIK3R3  2 0.632 3
 UniProt:Q96SB4 SRPK1  2 0.59 2
 UniProt:P56945 BCAR1  4 0.589 2
 UniProt:P07948 LYN  7 0.573 2
 UniProt:Q14451 GRB7  1 0.57 3
 UniProt:P29350-3 PTPN6      0.57 3
 UniProt:Q9NP31 SH2D2A  1 0.57 3
 UniProt:Q68CZ2 TNS3  1 0.556 3
 UniProt:P06241 FYN  6 0.547 3
 UniProt:Q824H6 Q824H6      0.543 3
 UniProt:P78396 CCNA1  3 0.536 2
 UniProt:P42224 STAT1  8 0.536 3
 UniProt:P04626 ERBB2  20 0.536 2
 UniProt:P05120 SERPINB2  2 0.527 2
 UniProt:Q62219 TGFI1      0.524 3
 UniProt:P16144 ITGB4  1 0.524 7
 UniProt:P08631-2 HCK      0.508 2
 UniProt:P29317 EPHA2  2 0.488 3
 UniProt:Q8TEW6 DOK4  1 0.488 2
 UniProt:O60880 SH2D1A  1 0.488 2
 UniProt:P13569 CFTR  17 0.483 10
 UniProt:Q80ZW7 Q80ZW7      0.463 2
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