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ETS2 [nucleoplasm]
Stable Identifier
R-HSA-1629811
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Protein C-ets-2
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oncogene Induced Senescence (Homo sapiens)
ERF inhibits ETS2 expression (Homo sapiens)
ETS2 [nucleoplasm] (Homo sapiens)
MAPKs phosphorylate ETS1 and ETS2 (Homo sapiens)
ETS1/ETS2 [nucleoplasm] (Homo sapiens)
ETS2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15036 ETS2
Gene Names
ETS2
Chain
chain:1-469
Reference Genes
BioGPS Gene:2114 ETS2
COSMIC (genes):ETS2 ETS2
CTD Gene:2114 ETS2
dbSNP Gene:2114 ETS2
ENSEMBL:ENSG00000157557 ETS2
HGNC:3489 ETS2
KEGG:hsa:2114 ETS2
Monarch:2114 ETS2
NCBI Gene:2114 ETS2
OMIM:164740 ETS2
UCSC:P15036 ETS2
Reference Transcript
RefSeq:XM_005260935.1 ETS2
RefSeq:XM_017028290.1 ETS2
RefSeq:NM_005239.5 ETS2
Other Identifiers
11742752_a_at
11758370_s_at
1519_at
16922779
201328_PM_at
201328_at
201329_PM_s_at
201329_s_at
2114
38739_at
3921081
3921082
3921083
3921084
3921085
3921086
3921093
3921098
3921100
3921101
3921102
3921105
3921107
3921108
3921109
3921110
3921112
3921115
3921116
3921117
3921118
3921119
3921120
8068593
A_14_P117113
A_23_P257924
A_24_P314179
A_24_P382661
GE54144
GE79512
GE88270
GO:0000122
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0001227
GO:0001501
GO:0001712
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0005886
GO:0006355
GO:0006357
GO:0007498
GO:0019904
GO:0035259
GO:0043226
GO:0043565
GO:0045944
GO:0048856
GO:0061629
GO:0090009
GO:0140110
GO:1990837
HMNXSV003039575
Hs.85146.0.A2_3p_at
ILMN_1720158
J04102_at
PH_hs_0023540
TC21000169.hg
g4885220_3p_a_at
Participates
as an output of
ERF inhibits ETS2 expression (Homo sapiens)
as a member of
ETS1/ETS2 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
p-T72-ETS2 [nucleoplasm]
Inferred To
Ets2 [nucleoplasm]
(Mus musculus)
Ets2 [nucleoplasm]
(Rattus norvegicus)
Homologues of ETS2 [nucleoplasm]
(Danio rerio)
Homologues of ETS2 [nucleoplasm]
(Xenopus tropicalis)
ets1 [nucleoplasm]
(Xenopus tropicalis)
pnt [nucleoplasm]
(Drosophila melanogaster)
ETS2 [nucleoplasm]
(Bos taurus)
ETS2 [nucleoplasm]
(Canis familiaris)
ETS2 [nucleoplasm]
(Gallus gallus)
ETS2 [nucleoplasm]
(Sus scrofa)
ets2 [nucleoplasm]
(Danio rerio)
ets2 [nucleoplasm]
(Xenopus tropicalis)
etv2 [nucleoplasm]
(Xenopus tropicalis)
etsrp [nucleoplasm]
(Danio rerio)
Cross References
RefSeq
XP_005260992.1
,
NP_005230.1
,
XP_016883779.1
ENSEMBL
ENST00000360214
,
ENST00000662305
,
ENST00000653642
,
ENST00000666778
,
ENST00000360938
,
ENSP00000499315
,
ENSP00000354194
,
ENSP00000499775
,
ENSP00000499226
,
ENSP00000353344
OpenTargets
ENSG00000157557
HPA
ENSG00000157557-ETS2
PRO
P15036
Pharos - Targets
P15036
PDB
4MHV
,
4BQA
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.602
4
UniProt:Q8NHY2 RFWD2
3
p-S387-RFWD2 [cytosol]
(R-HSA-349439)
RFWD2 [nucleoplasm]
(R-HSA-349454)
p-S387-RFWD2 [nucleoplasm]
(R-HSA-349450)
0.564
2
IntAct:EBI-25847655 CCSB
0.556
3
UniProt:P37173 TGFBR2
9
TGFBR2 [plasma membrane]
(R-HSA-170842)
NEDD8-K556,K567-TGFBR2 [plasma membrane]
(R-HSA-4332222)
TGFBR2 K128Sfs*35 [cytosol]
(R-HSA-3642166)
TGFBR2 K128Afs*3 [cytosol]
(R-HSA-3642173)
TGFBR2 R528C [plasma membrane]
(R-HSA-3640899)
TGFBR2 R528H [plasma membrane]
(R-HSA-3640894)
TGFBR2 D522N [plasma membrane]
(R-HSA-3640907)
TGFBR2 E526Q [plasma membrane]
(R-HSA-3645770)
TGFBR2 Y470D [plasma membrane]
(R-HSA-3640905)
0.556
3
UniProt:P17612 PRKACA
4
PRKACA [cytosol]
(R-HSA-57844)
PRKACA [nucleoplasm]
(R-HSA-111936)
PRKACA [ciliary base]
(R-HSA-5610402)
PRKACA [mitochondrial matrix]
(R-HSA-9838291)
0.556
3
UniProt:P50454 SERPINH1
1
SERPINH1 [endoplasmic reticulum lumen]
(R-HSA-2127480)
0.556
3
UniProt:Q15131 CDK10
0.524
2
UniProt:Q8WVJ9 TWIST2
1
TWIST2 [nucleoplasm]
(R-HSA-445444)
0.524
2
UniProt:Q15672 TWIST1
1
TWIST1 [nucleoplasm]
(R-HSA-445442)
0.524
2
UniProt:Q16236 NFE2L2
13
p-S40-NFE2L2 [nucleoplasm]
(R-HSA-9715109)
p-S,T-NFE2L2 [nucleoplasm]
(R-HSA-9715110)
p-S40-NFE2L2 [cytosol]
(R-HSA-8932290)
p-S,T-NFE2L2 [cytosol]
(R-HSA-8932311)
NFE2L2 [cytosol]
(R-HSA-201566)
p-S,T-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760033)
p-S40-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760018)
ub-NFE2L2 [cytosol]
(R-HSA-9758077)
ub-p-S335, S338,T-NFE2L2 [nucleoplasm]
(R-HSA-9762055)
ub-p-S40, S335, S338- NFE2L2 [nucleoplasm]
(R-HSA-9762058)
p-S344, S347,T-NFE2L2 [nucleoplasm]
(R-HSA-9762048)
p-S40, S344, S347- NFE2L2 [nucleoplasm]
(R-HSA-9762050)
p-S,T,S558-NFE2L2 [nucleoplasm]
(R-HSA-9795736)
0.508
2
UniProt:Q8NHY2-1 COP1
0.462
2
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