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SOX4 [nucleoplasm]
Stable Identifier
R-HSA-5625832
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Transcription factor SOX-4, SOX4_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Deactivation of the beta-catenin transactivating complex (Homo sapiens)
Beta-catenin binds SOX proteins (Homo sapiens)
CTNNB1:SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)
SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)
SOX4 [nucleoplasm] (Homo sapiens)
SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)
SOX4 [nucleoplasm] (Homo sapiens)
TCF:Beta-catenin binds SOX proteins (Homo sapiens)
SOX4,SOX13,SOX17 [nucleoplasm] (Homo sapiens)
SOX4 [nucleoplasm] (Homo sapiens)
TCF/LEF:CTNNB1:SOX4,SOX13,SOX17 [nucleoplasm] (Homo sapiens)
SOX4,SOX13,SOX17 [nucleoplasm] (Homo sapiens)
SOX4 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q06945 SOX4
Gene Names
SOX4
Chain
chain:1-474
Reference Genes
BioGPS Gene:6659 SOX4
COSMIC (genes):SOX4 SOX4
CTD Gene:6659 SOX4
dbSNP Gene:6659 SOX4
ENSEMBL:ENSG00000124766 SOX4
ENSEMBL_homo_sapiens_GENE:ENSG00000124766.7 SOX4
HGNC:11200 SOX4
KEGG Gene (Homo sapiens):6659 SOX4
Monarch:6659 SOX4
NCBI Gene:6659 SOX4
OMIM:184430 SOX4
UCSC:Q06945 SOX4
Reference Transcript
RefSeq:NM_003107.2 SOX4
Other Identifiers
11719559_at
11719560_at
11719561_s_at
11719562_at
11719563_a_at
11757741_s_at
11758525_s_at
17005276
201416_PM_at
201416_at
201417_PM_at
201417_at
201418_PM_s_at
201418_s_at
213668_PM_s_at
213668_s_at
2897900
2897901
2897902
2897903
2897904
2897905
2897906
2897907
2897908
2897909
2897910
2897911
2897912
2897913
2897914
2897915
2897916
2897917
2897918
2897920
33131_at
55646_at
6659
8117165
85332_at
A_14_P117119
A_14_P133803
A_14_P139984
A_23_P82169
A_24_P911676
GE498003
GE59973
GO:0000122
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001228
GO:0001666
GO:0002328
GO:0002376
GO:0003183
GO:0003215
GO:0003289
GO:0003357
GO:0003677
GO:0003700
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005739
GO:0006351
GO:0006355
GO:0007155
GO:0007399
GO:0007507
GO:0008284
GO:0008285
GO:0009653
GO:0010467
GO:0012501
GO:0014009
GO:0021510
GO:0021782
GO:0023052
GO:0030154
GO:0030217
GO:0031018
GO:0031397
GO:0031647
GO:0032024
GO:0035019
GO:0035198
GO:0035910
GO:0036211
GO:0042593
GO:0043065
GO:0043226
GO:0043516
GO:0045588
GO:0045662
GO:0045663
GO:0045727
GO:0045893
GO:0045944
GO:0048485
GO:0048856
GO:0050821
GO:0051604
GO:0060412
GO:0060485
GO:0060563
GO:0060993
GO:0061484
GO:0071333
GO:0090263
GO:0140110
GO:1990837
GO:2000761
HMNXSV003011621
Hs.83484.0.S1_3p_at
Hs.83484.0.S3_3p_at
Hs.83484.0.S3_3p_x_at
Hs.83484.1.S1_3p_a_at
ILMN_1815745
PH_hs_0024012
TC06000135.hg
TC06002615.hg
X70683_at
g4507162_3p_a_at
Participates
as a member of
SOX4,SOX13,SOX17 [nucleoplasm] (Homo sapiens)
SRY,SOX2,SOX3,SOX4,SOX6,SOX7,SOX9,SOX17 [nucleoplasm] (Homo sapiens)
Inferred To
sox-4 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of SOX4 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of SOX4 [nucleoplasm]
(Drosophila melanogaster)
Sox14 [nucleoplasm]
(Drosophila melanogaster)
SoxN [nucleoplasm]
(Drosophila melanogaster)
SOX4 [nucleoplasm]
(Bos taurus)
SOX4 [nucleoplasm]
(Canis familiaris)
SOX4 [nucleoplasm]
(Gallus gallus)
SOX4 [nucleoplasm]
(Sus scrofa)
D [nucleoplasm]
(Drosophila melanogaster)
sox-2 [nucleoplasm]
(Caenorhabditis elegans)
sox-3 [nucleoplasm]
(Caenorhabditis elegans)
Sox4 [nucleoplasm]
(Mus musculus)
Sox4 [nucleoplasm]
(Rattus norvegicus)
Sox21b [nucleoplasm]
(Drosophila melanogaster)
sem-2 [nucleoplasm]
(Caenorhabditis elegans)
Sox21a [nucleoplasm]
(Drosophila melanogaster)
sox4 [nucleoplasm]
(Xenopus tropicalis)
sox4b [nucleoplasm]
(Danio rerio)
Sox15 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_003098.1
OpenTargets
ENSG00000124766
HPA
ENSG00000124766-SOX4
GeneCards
Q06945
Ensembl
ENST00000244745
,
ENSG00000124766
,
ENSP00000244745
PRO
Q06945
Pharos - Targets
Q06945
Orphanet
28273
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.591
4
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