Reactome | IP6K2 [nucleoplasm]

IP6K2 [nucleoplasm]

Stable Identifier

R-HSA-1015687

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Inositol hexakisphosphate kinase 2, IP6K2_HUMAN, IHPK2, TCCCIA00113

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UHH9 IP6K2

Gene Names

IP6K2, IHPK2, TCCCIA00113

Chain

chain:1-426

Reference Genes

COSMIC (genes):IP6K2 IP6K2

ENSEMBL:ENSG00000068745 IP6K2

HGNC:17313 IP6K2

UCSC:Q9UHH9 IP6K2

Other Identifiers

11720648_a_at

11742962_a_at

11760101_a_at

11760969_a_at

11763863_x_at

16953701

218192_PM_at

218192_at

223165_PM_s_at

223165_s_at

2673686

2673687

2673688

2673689

2673690

2673691

2673693

2673694

2673695

2673696

2673697

2673698

2673699

2673700

2673701

2673702

2673703

2673704

2673705

2673706

2673707

2673708

2673709

2673710

2673711

2673712

2673713

2673714

2673715

2673716

2673718

2673719

2673720

2673721

2673722

2673723

2673725

2673726

2673732

2673764

2673766

2673770

46676_at

50973_s_at

51447

57052_at

8087201

A_23_P301133

A_23_P301138

A_23_P6836

GE56474

GO:0000827

GO:0000828

GO:0000829

GO:0000832

GO:0001650

GO:0003824

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0006629

GO:0016301

GO:0016740

GO:0030054

GO:0030308

GO:0032958

GO:0033138

GO:0043065

GO:0043226

GO:0043647

GO:0046488

GO:0046854

GO:0050821

GO:0052836

GO:0052839

GO:0097243

GO:0180030

GO:1905396

HMNXSV003009816

HMNXSV003011116

ILMN_1683328

ILMN_2328835

PH_hs_0016099

PH_hs_0032660

TC03001388.hg

TC03002898.hg

TC03002899.hg

g13325312_3p_a_at

g7705552_3p_at

Participates

as an output of

Expression of IFN-induced genes (Homo sapiens)

as a member of

IP6K1/2 [nucleoplasm] (Homo sapiens)

Inferred To

I6KA [nucleoplasm] (Dictyostelium discoideum)

IP6K2 [nucleoplasm] (Bos taurus)

IP6K2 [nucleoplasm] (Caenorhabditis elegans)

IP6K2 [nucleoplasm] (Canis familiaris)

IP6K2 [nucleoplasm] (Dictyostelium discoideum)

IP6K2 [nucleoplasm] (Gallus gallus)

IP6K2 [nucleoplasm] (Mus musculus)

IP6K2 [nucleoplasm] (Plasmodium falciparum)

IP6K2 [nucleoplasm] (Rattus norvegicus)

IP6K2 [nucleoplasm] (Saccharomyces cerevisiae)

IP6K2 [nucleoplasm] (Schizosaccharomyces pombe)

IP6K2 [nucleoplasm] (Sus scrofa)

Ip6k [nucleoplasm] (Drosophila melanogaster)

ip6k2a [nucleoplasm] (Danio rerio)

ip6k2 [nucleoplasm] (Xenopus tropicalis)

Homologues of IP6K2 [nucleoplasm] (Caenorhabditis elegans)

Homologues of IP6K2 [nucleoplasm] (Dictyostelium discoideum)

Homologues of IP6K2 [nucleoplasm] (Saccharomyces cerevisiae)

Homologues of IP6K2 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

ENSEMBL

ENSP00000331103, ENSP00000399052, ENST00000340879, ENSP00000414139, ENST00000446860, ENSP00000387759, ENST00000413298, ENSP00000400812, ENST00000328631, ENST00000416707, ENST00000431721, ENST00000432678, ENSP00000396203, ENSP00000341925

OpenTargets

ENSG00000068745

HPA

ENSG00000068745-IP6K2

PRO

Q9UHH9

Pharos - Targets

Q9UHH9

GlyGen

Q9UHH9

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N448 LNX2			0.668	3
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.602	4
UniProt:P07205 PGK2	1	PGK2 [cytosol] (R-HSA-6807622)	0.564	2
UniProt:P07900 HSP90AA1	8	HSP90AA1 [lysosomal lumen] (R-HSA-9622850) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912)	0.558	2
UniProt:Q8N680 ZBTB2			0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:O60568 PLOD3	1	PLOD3 [endoplasmic reticulum membrane] (R-HSA-1981135)	0.556	3
UniProt:Q93062 RBPMS			0.556	3

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