Reactome | BARD1 [nucleoplasm]

BARD1 [nucleoplasm]

Stable Identifier

R-HSA-5659775

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

BRCA1-associated RING domain protein 1

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External Reference Information

External Reference

UniProt:Q99728 BARD1

Gene Names

BARD1

Chain

chain:1-777

Reference Genes

COSMIC (genes):BARD1 BARD1

dbSNP Gene:580 BARD1

ENSEMBL:ENSG00000138376 BARD1

Participates

as an input of

as a component of

Other forms of this molecule

K6PolyUb,p-T714,T734-BARD1 [nucleoplasm]

p-T714,T734-BARD1 [nucleoplasm]

K6PolyUb-BARD1 [nucleoplasm]

BARD1 C83G [nucleoplasm]

BARD1 C50G [nucleoplasm]

BARD1 L44R [nucleoplasm]

BARD1 H68Y [nucleoplasm]

BARD1 W34R [nucleoplasm]

BARD1 G623W [nucleoplasm]

BARD1 C53W [nucleoplasm]

BARD1 C71Y [nucleoplasm]

BARD1 G623E [nucleoplasm]

Inferred To

BARD1 [nucleoplasm] (Bos taurus)

BARD1 [nucleoplasm] (Canis familiaris)

BARD1 [nucleoplasm] (Gallus gallus)

BARD1 [nucleoplasm] (Sus scrofa)

Bard1 [nucleoplasm] (Mus musculus)

Bard1 [nucleoplasm] (Rattus norvegicus)

Interactors (27)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38398 BRCA1	20	polySUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) monoSUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) BRCA1 M1411T [nucleoplasm] (R-HSA-9702140) BRCA1 M1400V [nucleoplasm] (R-HSA-9701202) BRCA1 L1407P [nucleoplasm] (R-HSA-9702135) BRCA1 Y777* [nucleoplasm] (R-HSA-9702765) BRCA1 S1009* [nucleoplasm] (R-HSA-9702755) BRCA1 P724Lfs12 [nucleoplasm] (R-HSA-9703778) BRCA1 S451 [nucleoplasm] (R-HSA-9702754) BRCA1 S864* [nucleoplasm] (R-HSA-9702752) BRCA1 P897Kfs5 [nucleoplasm] (R-HSA-9703782) BRCA1 N555Kfs17 [nucleoplasm] (R-HSA-9703781) BRCA1 Y1127Sfs6 [nucleoplasm] (R-HSA-9703780) BRCA1 S886Cfs16 [nucleoplasm] (R-HSA-9703802) BRCA1 V83Cfs2 [nucleoplasm] (R-HSA-9703800) BRCA1 T464Pfs11 [nucleoplasm] (R-HSA-9703807) BRCA1 G813Dfs2 [nucleoplasm] (R-HSA-9703549) BRCA1 V340Gfs6 [nucleoplasm] (R-HSA-9703804) BRCA1 Y655* [nucleoplasm] (R-HSA-9702769) BRCA1 W372* [nucleoplasm] (R-HSA-9702768)	0.958	20
UniProt:O95751 LDOC1			0.781	7
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.718	6
UniProt:P33240 CSTF2	1	CSTF2 [nucleoplasm] (R-HSA-72003)	0.702	8
ChEBI:61151 PAR			0.65	9
UniProt:Q05048 CSTF1	1	CSTF1 [nucleoplasm] (R-HSA-72001)	0.581	4
UniProt:O95453 PARN	1	PARN [cytosol] (R-HSA-430009)	0.577	4
ChEBI:16864 ADP-RIBOSE			0.558	2
UniProt:O75031 HSF2B			0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q5JR59-3 MTUS2			0.556	3
UniProt:O00471 EXOC5	2	EXOC5 [cytosol] (R-HSA-265045) EXOC5 [cytosol] (R-HSA-5623383)	0.556	3
UniProt:Q9Y2T1 AXIN2	4	AXIN2 [cytosol] (R-HSA-3640821) ub-AXIN2 [cytosol] (R-HSA-4641131) RibC-AXIN2 [cytosol] (R-HSA-3640842) Ub-RibC-AXIN2 [cytosol] (R-HSA-3640859)	0.556	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:Q8N720 ZNF655	1	ZNF655 [nucleoplasm] (R-HSA-2127575)	0.556	3
UniProt:Q13422-7 IKZF1			0.556	3
UniProt:Q9BVG8-5 KIFC3			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:Q8IZU0 FAM9B			0.556	3
IntAct:EBI-16435328 CCSB ORF ID			0.556	3
UniProt:Q15276 RABEP1	1	RABEP1 [early endosome membrane] (R-HSA-2029004)	0.556	3
UniProt:P38398-1 BRCA1			0.524	3
UniProt:Q9P2H0 CE126			0.508	2
UniProt:O95251 KAT7	1	KAT7 [nucleoplasm] (R-HSA-3321823)	0.508	2
UniProt:Q12873 CHD3	2	CHD3 [nucleoplasm] (R-HSA-4657012) monoSUMO1-K1971-CHD3 [nucleoplasm] (R-HSA-8956372)	0.508	2
UniProt:O14776 TCERG1	1	TCERG1 [nucleoplasm] (R-HSA-3246027)	0.508	2
UniProt:Q9Y2X7 GIT1	2	GIT1 [cytosol] (R-HSA-430326) p-Y383-GIT1 [cytosol] (R-HSA-3928463)	0.508	2

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